Results 21 to 30 of about 9,923 (187)
A Systematic Literature Review Exploring the Efficacy and Safety of Tadalafil and Sildenafil in Pulmonary Arterial Hypertension [PDF]
Pulmonary CirculationPulmonary Arterial Hypertension (PAH) is a rare, chronic and progressive disease affecting the heart and lungs. Endothelin receptor antagonist (ERA) + phosphodiesterase type 5 inhibitor (PDE5i) treatment is recommended for all PAH patients.
Rajan Saggar +9 more
doaj +2 more sources
Tadalafil: an overview and the post-mortem toxicology of a case
International Journal of Medical Toxicology and Forensic Medicine, 2023 Tadalafil is an inhibitor of the enzyme human cyclic guanosine monophosphate–specific phosphodiesterase, type 5 (PDE-5). A mild vasodilator, it is primarily used for the treatment of erectile dysfunction (ED), an increasingly common condition.
Maria Laura Schirripa +2 more
doaj +3 more sources
Enhanced Bioavailability of Tadalafil after Intranasal Administration in Beagle Dogs
Pharmaceutics, 2018 Tadalafil is an oral selective phosphodiesterase type-5 inhibitor with demonstrated efficacy and safety that is used to treat erectile dysfunction. The purpose of this study is to compare the pharmacokinetic properties of tadalafil after conventional ...
Jeong-Soo Kim, Min-Soo Kim, In-hwan Baek
doaj +2 more sources
LifeBackground/Objectives: Relationship quality is closely tied to sexual health. This study compared the effects of tadalafil cream and oral tadalafil on Dyadic Adjustment Scale (DAS) subscales and assessed the influence of age on treatment outcomes ...
Dragoș-Mihail Trifu +6 more
doaj +2 more sources
Scripta Score Scientific Medical JournalBackground: Benign prostatic hyperplasia (BPH) is a common urologic condition in aging men that often manifests as lower urinary tract symptoms (LUTS).
Mochammad Haikal Alhamdi +1 more
doaj +3 more sources
Portopulmonary hypertension practice patterns after liver transplantation
Liver Transplantation, EarlyView., 2022 Abstract Portopulmonary hypertension (POPH) is a type of pulmonary arterial hypertension occurring exclusively in those with portal hypertensive liver disease. Liver transplantation (LT) can significantly improve outcomes. Current guidelines counsel against immediate adjustments to targeted therapy after LT and suggest routine echocardiography as ...
Arun Jose +3 more
wiley +1 more source
A comparative Study of Tadalafil versus Tadalafil combined with Alpha Lipoic Acid in the treatment of Erectile Dysfunction in Diabetic Patients [PDF]
Al-Azhar International Medical Journal, 2022 Background: Erectile dysfunction (ED) is a worldwide health issue that has an influence on men's and their spouses' quality of life. The etiology of ED may be organic, psychogenic or mixed.
Hassan Abdel-Wahab +2 more
doaj +1 more source
BMJ Open Diabetes Research & Care, 2020 Introduction Sexual dysfunction is a common complication in men with type 2 diabetes and is often refractory to treatment. This study investigated the long-term influence of the phosphodiesterase 5 inhibitor (PDE5I) tadalafil on the level of sex hormones
Akiko Itoga +5 more
doaj +1 more source
Effect of Ticagrelor, a Cytochrome P450 3A4 Inhibitor, on the Pharmacokinetics of Tadalafil in Rats
Pharmaceutics, 2019 Tadalafil is a cytochrome P450 (CYP) 3A4 substrate. Because there are few data on drug-drug interactions, it is advisable to take sufficient consideration when co-administering tadalafil with CYP3A4 inducers or inhibitors.
Young-Guk Na +6 more
doaj +1 more source
BMC Urology, 2019 Background Chronic inflammation is thought to be a major causative factor for the development of benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS). Tadalafil, a phosphodiesterase type 5 inhibitor (PDE5-I), which has been used for
Mikio Sugimoto +11 more
doaj +1 more source