Results 41 to 50 of about 7,762 (135)

EFFECTS OF TADALAFIL ON CARDIOPULMONARY HAEMODYNAMICS IN PATIENTS OF CHRONIC PULMONARY DISEASES WITH PULMONARY HYPERTENSION: A PILOT STUDY

National Journal of Medical Research, 2016
Background and Objectives: Effect of tadalafil on cardiopulmonary haemodynamics in patients of chronic pulmonary diseases residing at an altitude has not been studied adequately.
Indrajeet Sharma, Purshottam K. Kaundal, Malay Sarkar, Tulika Jha, Prakash C. Negi   +4 more
doaj  

Development and Validation of Tadalafil Determination in Human Plasma by HPLC-MS Method

Разработка и регистрация лекарственных средств, 2019
Introduction. Tadalafil is a drug used to treat erectile dysfunction. For the quantitative determination of tadalafil in human plasma are used methods of high performance liquid chromatography with ultraviolet and tandem mass spectrometric detection ...
D. S. Bogdanova, T. N. Komarov, I. E. Shohin, E. S. Melnikov, O. A. Miskiv, Yu. V. Medvedev   +5 more
doaj   +1 more source

Comparing efficacy and safety of monotherapy and combination therapy with tadalafil, tamsulosin, and silodosin for distal ureteral stones: A systematic review and meta-analysis

Asian Journal of Urology
Objective: Medical expulsive therapy (MET) is a suitable option for facilitating stone expulsion in patients with distal ureteral stones. This meta-analysis was conducted to compare efficacy and safety of monotherapy and combination therapy with ...
Sholeh Ebrahimpour, Mona Kargar, Mohadeseh Balvardi, Ozra Tabatabaei-Malazy, Pardis Asadi, Mehdi Mohammadi   +5 more
doaj   +1 more source

Comparative Effects of Tadalafil Cream Versus Oral Tadalafil on Males with Erectile Disfunction Regarding Relationship Dynamics: A Secondary Analysis of Dyadic Adjustment Outcomes in a Randomized Crossover Trial

Life
Background/Objectives: Relationship quality is closely tied to sexual health. This study compared the effects of tadalafil cream and oral tadalafil on Dyadic Adjustment Scale (DAS) subscales and assessed the influence of age on treatment outcomes ...
Dragoș-Mihail Trifu, Daniel-Corneliu Leucuța, Martina-Luciana Pintea-Trifu, Florin Elec, Nicolae Crișan, Dan Eniu, Ioan Coman   +6 more
doaj   +1 more source

Postmortem Toxicology of Tadalafil in a Forensic Case

International Journal of Medical Toxicology and Forensic Medicine, 2023
Tadalafil is an inhibitor of the enzyme human cyclic guanosine monophosphate–specific phosphodiesterase, type 5 (PDE-5). A mild vasodilator, it is primarily used for the treatment of erectile dysfunction (ED), an increasingly common condition.
Maria Laura Schirripa, Letizia Gnetti, Edda Emanuela Guareschi   +2 more
doaj  

The effect of tadalafil therapy on kidney damage caused by sepsis in a polymicrobial septic model induced in rats: a biochemical and histopathological study

International Brazilian Journal of Urology
Introduction Sepsis is an inflammatory reaction to bacteria involving the whole body and is a significant cause of mortality and economic costs. The purpose of this research was to determine whether tadalafil exhibits a preventive effect on sepsis in a ...
Erdal Benli, Sema Nur Ayyildiz, Selma Cirrik, Sibel Koktürk, Abdullah Cirakoglu, Tevfik Noyan, Ali Ayyildiz, Cankon Germiyanoglu   +7 more
doaj   +1 more source

Histopathological and real–time PCR analysis of alterations in the rat brain within the Glycerol–induced Crush Syndrome

Revista Científica
This study attempted to examine the neuroprotective benefits of vitamin C and tadalafil in an experimental crush syndrome model induced by intramuscular glycerol injection in rats, using histopathological and real–time polymerase chain reaction.
Ayşegül Bulut, Mehmet Tuzcu, Mehmet Burak Ateş, Şeyma Hazal Çetin, Vedat Kaya   +4 more
doaj   +1 more source

The Efficacy and Safety of Tamsulosin and Tadalafil Combination Therapy Compared with Tadalafil Alone for Patients with Benign Prostatic Hyperplasia

Scripta Score Scientific Medical Journal
Background: Benign prostatic hyperplasia (BPH) is a common urologic condition in aging men that often manifests as lower urinary tract symptoms (LUTS).
Mochammad Haikal Alhamdi, Siti Nurhijrati Hasanah   +1 more
doaj   +1 more source

Combination of tadalafil and finasteride for improving the symptoms of benign prostatic hyperplasia: critical appraisal and patient focus

Therapeutics and Clinical Risk Management, 2015
Osama O Elkelany, Ryan C Owen, Edward D KimDepartment of Surgery, Division of Urology, University of Tennessee Graduate School of Medicine, Knoxville, TN, USAAbstract: The evidence suggests that combination therapy for benign prostatic hyperplasia (BPH ...
Elkelany OO, Owen RC, Kim ED
doaj  

The Potential Therapeutic Effects of Tadalafil on the Endothelium in a Subarachnoid Hemorrhage Animal Model: Insights from Immunohistochemical Staining

Current Issues in Molecular Biology
This study investigated the potential of phosphodiesterase type 5 (PDE-5) inhibitors, specifically tadalafil, in preventing the delayed cerebral ischemia (DCI) post-rupture of cerebral aneurysms.
Kwang Hyon Park, Hyon-Jo Kwon, Eun-Oh Jeong, Hyeon-Song Koh, Jeongwook Lim   +4 more
doaj   +1 more source