Results 41 to 50 of about 10,553 (193)

The effect of phosphodiesterase-5 inhibitor, tadalafil, on in vitro potassium chloride-induced contractions of isolated human ureteral tissue

Indian Journal of Urology, 2018
Introduction: Drugs causing ureteral relaxation are used for medical expulsive therapy (MET) for stones. We investigated the in vitro ability of tadalafil to cause relaxation of potassium chloride (KCl)-induced contractions of isolated human ureteral ...
M S Sakthivel, Ratna Prabha, Onkar Singh, Nitin S Kekre, Santosh Kumar   +4 more
doaj   +1 more source

From nature to nanoscale: advances, challenges, and preclinical translation of nanofiber drug delivery systems containing plant‐derived active ingredients

Journal of the Science of Food and Agriculture, EarlyView.
Abstract Since the early 1960s, nanotechnology has been a critical area of science, allowing for the development of sophisticated nanomaterials. Nanofibers, one of the most widely used nanotechnological drug delivery systems, have emerged as a highly versatile platform within modern pharmaceutical sciences.
Heybet Kerem Polat, Yasin Turanlı, Nihat Kurt, Sefa Gözcü, Emre Tunçel, Hilal Bacanak, Eren Aytekin, Sedat Ünal   +7 more
wiley   +1 more source

Tadalafil [PDF]

pharma-kritik, 2005
Ein lang wirkender Phosphodiesterasehemmer zur Behandlung der erektilen Dysfunktion.
openaire   +1 more source

The Benefits of Adding Non‐Antimuscarinic Pharmaceuticals in Combination With Beta‐3 Agonists for Overactive Bladder Treatment: A Systematic Review

Neurourology and Urodynamics, EarlyView.
ABSTRACT Introduction Antimuscarinics, as the current first‐line pharmacologic therapies for overactive bladder, exhibit low patient adherence and high rates of reported side effects. As a modern alternative pharmaceutical treatment, beta‐3 agonists, which relax the urinary bladder, may be more tolerable for patients, increasing adherence and ...
Felicity Smith, Charlotte Phelps, Christian Moro   +2 more
wiley   +1 more source

Evaluation of testosterone and prolactin hormones levels in erectile dysfunction patients after single oral dose of Tadalafil

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2008
Erectile dysfunction (ED) is defined as a consistent inability to sustain an erection sufficient for sexual intercourse. Tadalafil is a selective, reversible inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5 ...
Hayder Hamed Abed
doaj   +1 more source

Myopathy with Concurrent Tadalafil and Simvastatin [PDF]

, 2009
A 48-year-old man, using statin, was admitted to hospital with progressive myalgia after consumption of tadalafil and simvastatin. Muscle pain and penile erection disappeared seven days after interruption of therapy.
Cristina Russo, Marco Vacante, Mariano Malaguarnera, Maria Pia Gargante   +3 more
core   +1 more source

Male Sexual and Reproductive Health in Diabetes and Obesity Pharmacotherapy: A Source‐Triangulated Counseling Map

Andrology, EarlyView.
ABSTRACT Background Drugs used for diabetes and obesity increasingly shape male sexual and reproductive counseling, but clinical studies, trial registrations, regulatory labels, and patents answer different questions. Objectives The objective is to map these sources and define what each can support when counseling men receiving metabolic drugs ...
Marek Broul, Michal Dubský, Aneta Hujová, Michaela Liegertová   +3 more
wiley   +1 more source

The Impact of Common Medications on Male Fertility: An Updated Systematic Review

Andrology, EarlyView.
ABSTRACT Background Compared with those of cytotoxic treatments, the potential effects of common medications on the fertility of men trying to conceive currently or planning to conceive in the future are less well described. The use of common medications may modify the gonadotropic axis, spermatogenesis, and epididymal maturation or alter male ...
Lina Jebli, Salomé Gallissian, Roxanne Barèges, Félicia Fournier, Catherine Metzler‐Guillemain, Ségolène Prades, Fanny Magnan‐Sebag, Jeanne Perrin   +7 more
wiley   +1 more source

Efficacy of Tadalafil Add-on Treatment for Men with Lower Urinary Tract Symptoms Refractory to Alpha-1 Adrenoceptor Blockers [PDF]

, 2017
Introduction：To evaluate the efficacy and safety of once daily phosphodiesterase type 5 inhibitor(PDE5i) tadalafil as an add-on treatment for men with lower urinary tract symptoms suggestive of benign prostatic hyperplasia（BPH/LUTS）refractory to an alpha
Arai, Gaku, Yagi, Hiroshi, Soh, Shigehiro, Okada, Hiroshi   +3 more
core  

Modulating phosphodiesterase-5 activity to suppress the immunosuppressive mechanisms of myeloid-derived suppressor cells in breast cancer

Breast Cancer Research
Phosphodiesterase-5 (PDE5) inhibitors have been shown to have potential as an adjuvant therapy for cancer. Tadalafil is a potent and selective PDE5 inhibitor that has been shown to inhibit the aggregation of myeloid-derived suppressor cells (MDSC) within
Yingxue Guo, Mengyun Chen, Qi Yuan, Jie Huang, Wen Mao, Xianli Liu, Lu Jin, Lijia Chen, Jingyi Lou, Xia Liu, Qi Pan, Huiying Fu, Qiyang Shou   +12 more
doaj   +1 more source