Results 41 to 50 of about 9,923 (187)

Kiwifruit Extract Attenuates Tadalafil Induced Retinal Injury in Adult Male Albino Rats: A Histological and Immunohistochemical Study [PDF]

The Egyptian Journal of Histology, 2020
Background: Tadalafil is a one of the commonly prescribed drugs for treatment of erectile dysfunction. Several ocular side effects have been reported with tadalafil therapy.
Amira Kassab, Walaa Elwan
doaj   +1 more source

Tadalafil-loaded PLGA microspheres for pulmonary administration: preparation and evaluation

, 2019
Tadalafil, a long-acting PED-5 inhibitor, is commonly used for the treatment of pulmonary arterial hypertension (PAH). However, its efficacy and clinical application are severely limited by the poor water solubility, low bioavailability and a series ...
Liu Tian (12848781), Xiuping Zhang (334570), Guihua Huang (11757071), Longmei Wang (4333165), Zhenlei Yang (12848778)   +4 more
core   +1 more source

Bioequivalence and food effect of a fixed‐dose combination of macitentan and tadalafil: Adaptive design in the COVID‐19 pandemic

Pharmacology Research & Perspectives, 2021
The COVID‐19 pandemic has forced clinical studies to accommodate imposed limitations. In this study, the bioequivalence part could not be conducted as planned.
Dénes Csonka, Vladislav Fishman, Jaya Natarajan, Hans Stieltjes, Danielle Armas, Victor Dishy, Juan Jose Perez Ruixo   +6 more
doaj   +1 more source

Single and combined toxicity of tadalafil (Cilais) and microplastic in Tilapia fish (Oreochromis niloticus)

Scientific Reports
The joint impact of tadalafil (Cilais) as a pharmaceutical residue and microplastics on fish is not well comprehended. The current study examined haematological, biochemical, and antioxidant parameters, along with immunohistochemical and histological ...
Mahmoud S. Sabra, Alaa El-Din H. Sayed, Shaimaa K. A. Idriss, Hamdy A. M. Soliman   +3 more
doaj   +1 more source

Health-Care Resource Utilization and Treatment Patterns in Men with Erectile Dysfunction and Benign Prostatic Hyperplasia-Associated Lower Urinary Tract Symptoms in the United States: A Retrospective Database Study

Patient Preference and Adherence, 2023
Irwin Goldstein,1 Tarek Hassan,2 Kelly Zou,3 Victoria Divino,4 Mitch DeKoven,4 Joseph Imperato,3 Vamshi Ruthwik Anupindi,4 Jim Li3 1Department of Sexual Medicine, Alvarado Hospital, San Diego, CA, USA; 2Department of Urology, Viatris Inc, Canonsburg, PA,
Goldstein I, Hassan T, Zou K, Divino V, DeKoven M, Imperato J, Anupindi VR, Li J   +7 more
doaj  

Simultaneous spectrophotometric determination of finasteride and tadalafil in recently FDA approved Entadfi™ capsules

BMC Chemistry, 2022
Entadfi™ is a recently FDA approved pharmaceutical combination capsule of finasteride and tadalafil. It was prescribed for the treatment of urinary tract disorders caused by benign prostatic hyperplasia in men.
Ahmed H. Abdelazim, Sherif Ramzy
doaj   +1 more source

Design of Single‐Atom Nanozymes for Precision Treatment of Erectile Dysfunction with Integrated Single‐Cell RNA Sequencing and Machine Learning

Advanced Science, EarlyView.
It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou, Xi Zhang, Sihan Chen, Mengchi Yu, Yilan Hu, Chi Gan, Xianghu Meng, Long Li, Ninghong Song   +8 more
wiley   +1 more source

A phase 3 randomized placebo-controlled trial of tadalafil for Duchenne muscular dystrophy. [PDF]

, 2017
peer reviewedOBJECTIVE: To conduct a randomized trial to test the primary hypothesis that once-daily tadalafil, administered orally for 48 weeks, lessens the decline in ambulatory ability in boys with Duchenne muscular dystrophy (DMD).
Wolfgang Mueller-Felber, Tadalafil DMD Study Group, Susan Iannaccone, Pereon, Yann, Russell Butterfield, Dubrovsky, A.L., Finkel, Richard, Schallner, Jens, Cox, D., Haluk Topaloglu, Susan Sparks, Finkel, R., Butterfield, Russell, Dubrovsky, Alberto AL, Cox, David A., Victor RG, null null, Vandenborne, Krista, Saleel Chandratre, Ben Renfroe, Belousova, Elena, Selby, Kathryn, Mcdonald, Craig M, Dooley, Joseph, Claudio Bruno, Robert Elashoff, Chae, Jong-Hee, Pat Furlong, Jean Mah, Anne Connolly, Susan Apkon, McDonald, C.M., Sparks, Susan, Michelle Eagle, de Munain, Adolfo Lopez, Kirschner, JanBerd, McDonald, Craig M., Cox David, Hattori, Ayako, Eagle M, Giacomo Comi, Wilichoswki, Ekkehard, Victor, R.G., Wang-Tso Lee, Janas, Joanne, Sendra, Isabel Illa, Elashoff, Robert, Dubrovsky, Alberto, Hoda Abdel-Hamid, McDonald, Craig, Sanka, Ratna Bhavaraju, Miceli, Carrie MC, Enrico Bertini, Eagle, M., Dubrovsky AL, Jong-Hee Chae, Katherine Mathews, JanBerd Kirschner, Katsuhisa Ogata, Finkel, Richard S., Miceli, MC, Matthew Wicklund, Sweeney HL, Finkel, Richard RS, John Landry, Yuh-Jyh Jong, Bertini, Enrico, McDonald CM, Sweeney, H. Lee, Sweeney, Lee HL, Landry J, Kuntz, Nancy, Group, Tadalafil DMD Study, Harper, Amy, Kathryn Selby, Campbell, Craig, Pascual, Samuel, Connolly, Anne, Elashoff R, Hirofumi Komaki, Edward Smith, William Burnette, Tadalafil DMD Study Grp, Bruno, Claudio, Mueller-Felber, Wolfgang, Topaloglu H, Victor, Ronald G, Vandenborne K, Miceli, M. Carrie, Erik Niks, Sweeney, H.L., Eugenio Mercuri, Burnette, William, Lee, Wang-Tso, David Cox, Victor, Ron, Cox, David, Isabel Illa Sendra, Jong, Yuh-Jyh, H. Lee Sweeney, Furlong P, McMillan, Hugh, Dubrovsky, Alberto L, Jose Carlo, Juan Jose Vilchez, Carlo, Jose, Vilchez, Juan Jose, Jens Schallner, Krista Vandenborne, Goemans N, Renfroe, Ben, Mah, Jean, Victor, Ronald G., Joanne Janas, Craig McDonald, Hugh McMillan, Joseph Dooley, Richard Finkel, Finkel R, Sweeney, H Lee, Nicolas Deconinck, Ronald G. Victor, Byrne B, De Groot, Imelda, Herguner, Ozlem, Goemans, Nathalie, Wong, Brenda, Iannaccone, Susan, Dubrovsky, Alberto L., Comi, Giacomo, Ozlem Herguner, Imelda De Groot, Adolfo Lopez de Munain, Schara, Ulrike, Eagle, Michelle, Mathews, Katherine, Edward Leung, Elena Pegoraro, Frank, L Matthew, Leung, Edward, Tadalafil DMD Study Group,, Landry, John, Cox D, Ogata, Katsuhisa, Wicklund, Matthew, Pegoraro, Elena, Miceli, M Carrie, Laurent Servais, Barry Byrne, Byrne, B., Topaloglu, H., John Brandsema, Samuel Pascual, Yann Pereon, Niks, Erik, Brandsema, John, Ulrike Schara, Landry, J., Servais, Laurent, Byrne, Barry, Elashoff, Robert M., Barohn, Richard, Tadalafil DMD, [Study group], Craig M. McDonald, Elashoff, R., Akinori Nakamura, Mercuri, Eugenio, Amy Harper, Ratna Bhavaraju Sanka, L Matthew Frank, Julien Durigneux, Nancy Kuntz, Abdel-Hamid, Hoda, Nakamura, Akinori, Ayako Hattori, Nathalie Goemans, Deconinck, Nicolas, Ron Victor, Alberto L. Dubrovsky, Goemans, N., Ekkehard Wilichoswki, Miceli MC, Miceli, M.C., Richard Barohn, Apkon, Susan, Alberto Dubrovsky, Elena Belousova, Durigneux, Julien, Topaloglu, Haluk, Smith, Edward, Vandenborne, K., Furlong, Pat, Craig Campbell, Furlong, P., Chandratre, Saleel, M. Carrie Miceli, Komaki, Hirofumi, Brenda Wong, Finanger, Erika, Erika Finanger   +199 more
core   +1 more source

Development of a skeleton-specific antibody and Au nanoparticle-based immunochromatographic sensor for simultaneous detection of various tadalafil adulterants in health food

Food and Agricultural Immunology, 2019
In this work, a rapid, convenient and sensitive Au nanoparticle-based immunochromatographic sensor (AuNPs-ICS) for simultaneous detection of various tadalafil adulterants in health food was established for the first time, based on one high affinity and ...
Fan He, Tingting Zou, Jinyi Yang, Hong Wang, Lihua Deng, Yuanxin Tian, Zhenlin Xu, Yuanming Sun, Hongtao Lei, Xuecai Tan, Yudong Shen   +10 more
doaj   +1 more source

The effect of phosphodiesterase-5 inhibitor, tadalafil, on in vitro potassium chloride-induced contractions of isolated human ureteral tissue

Indian Journal of Urology, 2018
Introduction: Drugs causing ureteral relaxation are used for medical expulsive therapy (MET) for stones. We investigated the in vitro ability of tadalafil to cause relaxation of potassium chloride (KCl)-induced contractions of isolated human ureteral ...
M S Sakthivel, Ratna Prabha, Onkar Singh, Nitin S Kekre, Santosh Kumar   +4 more
doaj   +1 more source