Maternal Blood Concentration of Tadalafil and Uterine Blood Flow in Pregnancy
Medicina (Lithuania), 2019 Background and Objectives: Tadalafil for treatment of fetal growth restriction (FGR) or preeclampsia is given once a day orally. The drug kinetics of tadalafil were investigated to determine the ideal dosage to promote uterine blood flow.
Hiroaki Tanaka +2 more
exaly +4 more sources
Potential of tadalafil and tadalafil-cellulose nanocomposite in preventing postsurgical abdominal adhesions in a rat cecal abrasion model [PDF]
Scientific ReportsThe formation of postoperative intra-abdominal adhesions is a significant challenge in veterinary practice worldwide. Thus, several attempts have been made to identify agents that prevent the occurrence of these postsurgical adhesions.
Ahmed Abdelrahiem Sadek +4 more
doaj +3 more sources
Redo pelvic fracture urethral injury repair: The case for tadalafil
Urology Research and Practice, 2021 Objective: To define the role of tadalafil in improving outcomes of redo urethroplasty for pelvic fracture urethral injury (PFUI). PFUI is common in developing countries, invariably as a result of road traffic trauma.
Devashree P. Joshi +5 more
doaj +2 more sources
Journal of Pharmacological Sciences, 2022 Podocyte injury is responsible for nephrotic syndrome. Previously, we found that tadalafil, a phosphodiesterase 5 inhibitor, might have protective effects on podocytes.
Natsumi Tomita +7 more
doaj +2 more sources
Association of Pericardial Tamponade With Initiation of Sotatercept in a Patient With Eisenmenger Syndrome [PDF]
Pulmonary Circulation, Volume 16, Issue 2, June 2026.ABSTRACT Eisenmenger syndrome (ES) represents an advanced stage of pulmonary arterial hypertension (PAH) associated with congenital heart disease. It is characterized by elevated pulmonary vascular resistance, with a right‐to‐left shunt and resting hypoxemia. ES is associated with high morbidity and mortality.
Khalifah A. Aldawsari +3 more
wiley +2 more sources
Comparative efficacy of on-demand Sildenafil, Tadalafil and daily Tadalafil for treatment of erectile dysfunction: A 12-week randomized controlled study [PDF]
Indian Journal of PsychiatryBackground: Comparison of available first line agents for treating Erectile Dysfunction (ED) with each other regarding efficacy in Indian context remains scant.
Shevya Gagal +3 more
doaj +2 more sources
Therapeutic Advances in Respiratory Disease, 2013 The purpose of this review is to evaluate the use of tadalafil as monotherapy and in combination regimens for the treatment of pulmonary arterial hypertension (PAH).
Dioma U. Udeoji, Ernst R. Schwarz
doaj +2 more sources
Modulating phosphodiesterase-5 activity to suppress the immunosuppressive mechanisms of myeloid-derived suppressor cells in breast cancer [PDF]
Breast Cancer ResearchPhosphodiesterase-5 (PDE5) inhibitors have been shown to have potential as an adjuvant therapy for cancer. Tadalafil is a potent and selective PDE5 inhibitor that has been shown to inhibit the aggregation of myeloid-derived suppressor cells (MDSC) within
Yingxue Guo +12 more
doaj +2 more sources
EFFECTS OF TADALAFIL AND/OR SILYMARIN ON GONADAL FUNCTION IN ADULTS MALE ALBINO RATS [PDF]
Basrah Journal of Veterinary Research, 2018 Taldalafil is a long acting phosphodiesterase-5 inhibitor widely used in the treatment of erectile dysfunction.
doaj +2 more sources
Transitioning From Oral to Intravenous Treprostinil in Pulmonary Arterial Hypertension: A Case Report [PDF]
Clinical Case Reports, Volume 14, Issue 4, April 2026.ABSTRACT The optimal approach to transitioning from oral treprostinil to intravenous treprostinil in pulmonary arterial hypertension (PAH) has been poorly characterized in published literature. We present a case involving a 21‐year‐old male with PAH experiencing worsening symptoms despite treatment with high doses of oral treprostinil (36.75 mg three ...
Abigail M. Cummings +3 more
wiley +2 more sources