Results 1 to 10 of about 10,149 (228)
A comparative analysis of topological domain callers over RNA-associated interactome [PDF]
BMC BioinformaticsBackground Topological domains (TADs) are consecutive genomic locations with denser local interactions to a certain extent, and they are important for cellular gene expression control and modulation.
Tuna Alaygut, Emre Sefer
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Deciphering chromatin domain, domain community and chromunity for 3D genome maps with Mactop [PDF]
Communications BiologyAdvanced high-throughput chromosome conformation capture techniques, like Hi-C, reveal genome organization into structural units like topologically associating domains (TADs), which are crucial in gene expression regulation.
Ran Duan +4 more
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Cell ReportsSummary: Topologically associated domains (TADs) are interaction subnetworks of chromosomal regions in 3D genomes. TAD boundaries frequently coincide with genome breaks while boundary deletion is under negative selection, suggesting that TADs may ...
Caelinn James +2 more
exaly +3 more sources
Occurrence of infectious bronchitis in layer birds in Plateau state, north central Nigeria [PDF]
Open Veterinary Journal, 2019 A flock of 54 week-old layer birds exhibiting signs of respiratory distress, greenish diarrhea and drop in egg production was investigated. A marked drop in egg production (55%) was recorded with eggs appearing white and soft-shelled.
Ismaila Shittu +7 more
doaj +1 more source
Molecular & Cellular Oncology, 2016 Ataxia telangiectasia mutated (ATM) has been known for decades as the main kinase mediating the DNA double-strand break response. Our recent findings suggest that its major role at the sites of breaks likely resides in its ability to modify both the local chromatin landscape and the global chromosome organization in order to promote repair accuracy.
Aymard, Francois, Legube, Gaëlle
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Oral microbiome contributes to the failure of orthodontic temporary anchorage devices (TADs)
BMC Oral Health, 2023 Background The stability of temporary anchorage devices (TADs) is critical in orthodontic clinics. The failure of TADs is multifactorial, and the role of the oral microbiome has not been clearly defined.
Ningrui Zhao +7 more
doaj +1 more source
TADs or no TADS: Lessons From Single-cell Imaging of Chromosome Architecture [PDF]
Journal of Molecular Biology, 2020 Eukaryotic genomes are folded in a hierarchical organization that reflects and possibly regulates their function. Genomewide studies revealed a new level of organization at the kilobase-to-megabase scale termed "topological associating domains" (TADs).
Cardozo Gizzi, Andrés M. +2 more
openaire +3 more sources
Analysis of oral microbiome on temporary anchorage devices under different periodontal conditions
Progress in Orthodontics, 2023 Background Temporary anchorage devices (TADs) are maximum anchorages that have been widely used in orthodontic treatment. The aim of the study was to uncover whether a history of periodontitis would influence microbiome colonization on the TAD surface ...
Ningrui Zhao +6 more
doaj +1 more source
Making sense of the linear genome, gene function and TADs
Epigenetics & Chromatin, 2022 Background Topologically associating domains (TADs) are thought to act as functional units in the genome. TADs co-localise genes and their regulatory elements as well as forming the unit of genome switching between active and inactive compartments.
Helen S. Long +5 more
doaj +1 more source
MH cortical screws, a revolutionary orthodontic TADs design
Journal of Orthodontic Science, 2022 OBJECTIVE: MH cortical screws were designed to combine the advantages of thick mini-implants with the versatility of micro-screws while avoiding the disadvantages of both.
Mohamed A Elkolaly, Hasan S Hasan
doaj +1 more source