Results 11 to 20 of about 13,596 (270)
Psychometric properties of the Trauma and Distress Scale, TADS, in an adult community sample in Finland [PDF]
Background: There is increasing evidence that a history of childhood abuse and neglect is not uncommon among individuals who experience mental disorder and that childhood trauma experiences are associated with adult psychopathology.
Raimo K. R. Salokangas +9 more
doaj +5 more sources
TADs or no TADS: Lessons from single-cell imaging of chromosome architecture [PDF]
Eukaryotic genomes are folded in a hierarchical organization that reflects and possibly regulates their function. Genomewide studies revealed a new level of organization at the kilobase-to-megabase scale termed “topological associating domains” (TADs ...
Cardozo Gizzi, Andres Mauricio +4 more
core +4 more sources
TADs: an evolutionary road to success
This is a literature search about the clinical use of temporary anchorage devices (TADs) as a means of providing effective orthodontic anchorage.
Audrey Pace, Jonathan Sandler
core +3 more sources
Overcoming Artificial Structures in Resolution-Enhanced Hi-C Data by Signal Decomposition and Multi-Scale Attention. [PDF]
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Li Q +6 more
europepmc +2 more sources
Ataxia telangiectasia mutated (ATM) has been known for decades as the main kinase mediating the DNA double-strand break response. Our recent findings suggest that its major role at the sites of breaks likely resides in its ability to modify both the local chromatin landscape and the global chromosome organization in order to promote repair accuracy.
Aymard, Francois, Legube, Gaëlle
openaire +2 more sources
Anchorage is one of the important aspects of orthodontic treatment TAD have gained profound applications in contemporary orthodontic protocol. To treat almost every genre of malocclusion be it arising from dentoalveolar component, skeletal component or combination of both Various skeletal anchorage devices were introduced in the 20th century which ...
Sharath Kumar Shetty +3 more
openaire +1 more source
TADs of eight Gossypium species.
TADs of eight Gossypium ...
Jianying Li (9426689)
core +1 more source
A study in Nature Genetics shows that genomic rearrangements that cause extensive changes to chromatin topology do not alter expression for the majority of genes.
openaire +2 more sources
Cohesin-sensitive genes are clustered and coordinated within TADs.
(A) The observed average percentage of NIPBL DEGs per TAD compared to a null distribution (expected). Permutations generated by shuffling the DEG and nonDEG designations across genes 1,000 times. Analysis limited to TADs with at least one expressed gene.
Rebecca Yunker (14197613) +10 more
core +1 more source
CTCF as a boundary factor for cohesin-mediated loop extrusion: evidence for a multi-step mechanism
Mammalian genome structure is closely linked to function. At the scale of kilobases to megabases, CTCF and cohesin organize the genome into chromatin loops.
Anders S. Hansen
doaj +1 more source

