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Journal of Molecular Biology, 2020
Developments in proximity ligation methods and sequencing technologies have provided high-resolution views of the organization of the genome inside the nucleus. A prominent feature of Hi-C maps is regions of increased self-interaction called topologically associating domains (TADs).
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Developments in proximity ligation methods and sequencing technologies have provided high-resolution views of the organization of the genome inside the nucleus. A prominent feature of Hi-C maps is regions of increased self-interaction called topologically associating domains (TADs).
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2023
ABSTRACT Topological associating domains (TADs) are self-interacting genomic units crucial for shaping gene regulation patterns. Despite their importance, the extent of their evolutionary conservation and its functional implications remain largely unknown.
Mariam, Okhovat +24 more
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ABSTRACT Topological associating domains (TADs) are self-interacting genomic units crucial for shaping gene regulation patterns. Despite their importance, the extent of their evolutionary conservation and its functional implications remain largely unknown.
Mariam, Okhovat +24 more
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A “Tad” of Science Appreciation
Early Childhood Education Journal, 2006One year, when we were living in Alabama, I grew watermelons in the backyard garden. I tied the vines to the wooden fence and the watermelon fruits hung down from them—so perfectly ellipsoidal and smooth! It was such a pleasure to see their symmetrical shape with even, green coloring and distinct black markings,—no yellow or brown spots like ground ...
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American Journal of Orthodontics and Dentofacial Orthopedics, 2009
Jennifer L, Cleveland, William, Kohn
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Jennifer L, Cleveland, William, Kohn
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American Journal of Orthodontics and Dentofacial Orthopedics, 2009
HyeRan, Choo +2 more
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HyeRan, Choo +2 more
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Genome Research
As crucial chromatin structures, hierarchical TADs play important roles in epigenetic organization, transcriptional activity, gene regulation, and cell differentiation. Currently, it remains a highly challenging task to accurately identify hierarchical TADs in a computational manner. The key bottleneck for existing TAD callers lies in the difficulty in
Yangyang, Liu +2 more
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As crucial chromatin structures, hierarchical TADs play important roles in epigenetic organization, transcriptional activity, gene regulation, and cell differentiation. Currently, it remains a highly challenging task to accurately identify hierarchical TADs in a computational manner. The key bottleneck for existing TAD callers lies in the difficulty in
Yangyang, Liu +2 more
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2001
This final chapter introduces the TAD case-tool. This software implements most of the algorithms of TAD methodology described in the previous chapters. The purpose of developing such a case-tool is to support the use of the methodology and to enable the reader to test the ideas and concepts of the methodology explained in different phases and steps.
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This final chapter introduces the TAD case-tool. This software implements most of the algorithms of TAD methodology described in the previous chapters. The purpose of developing such a case-tool is to support the use of the methodology and to enable the reader to test the ideas and concepts of the methodology explained in different phases and steps.
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TADs: Dynamic structures to create stable regulatory functions
Current Opinion in Structural Biology, 2023Daan Noordermeer
exaly

