Foundation model reveals the shared organization of transcription and topologically associating domains. [PDF]
Liang H, Berger B, Singh R.
europepmc +1 more source
ABSTRACT Background and Aims African Swine Fever (ASF) is a highly fatal viral disease of pigs that has persisted in Ghana since its first introduction in 1999, causing recurrent outbreaks with devastating socioeconomic consequences for livelihoods and food security.
Emmanuel Allege‐Cudjoe +23 more
wiley +1 more source
Success Rate of Immediately Loaded Orthodontic Temporary Anchorage Devices: A Retrospective Analysis of Patient- and Treatment-Related Factors. [PDF]
Martha K +5 more
europepmc +1 more source
Strategies and mechanisms of precision genome engineering: From gene editing to genome writing
In this review, we examined the progression of genome manipulation from stochastic nuclease‐mediated cutting toward precise editing and programmable genome writing. We discussed tools like multi‐kilobase RNA‐guided integrators and Artificial Intelligence (AI)‐designed effectors and showed how these advances enable researchers to treat genomes as ...
Kerui Huang +19 more
wiley +1 more source
Phase separation of ecDNA condensates establishes in-trans contact domains that boost selective MYC regulatory interactions. [PDF]
Conte M +9 more
europepmc +1 more source
ABSTRACT Background Sheeppox and goatpox are systemic, contagious viral diseases of small ruminants caused by sheep and goat pox viruses of the genus capripoxvirus. These diseases cause fever, generalised skin lesions and negatively affect health, economics and welfare.
Gerald Nizeyimana +7 more
wiley +1 more source
Genome folding and nuclear speckles converge to orchestrate fibroblast activation. [PDF]
Gardner Z +12 more
europepmc +1 more source
Abstract In situ observations of thermospheric composition have long been scarce, limiting our understanding of the upper atmosphere and its response to space weather. This study focuses on the Neutral Gas Mass Spectrometer (NGMS) onboard the TM19 and TM20 satellites of China's TianMu‐1 constellation, presenting the first systematic elaboration of its ...
Jiangzhao Ai +11 more
wiley +1 more source
Systematic evaluation of the heterogeneity of topologically associating domain boundaries in a large genomic context in humans. [PDF]
Sun Y +3 more
europepmc +1 more source
Native habitat affinities predict fish invasions with post‐invasion habitat shifts
Initial invasion success is gated by native pre‐adaptations, but post‐invasion establishment is characterized by habitat shifts. We demonstrate that forecasting risk based solely on native niches severely underestimates future ecological impacts, and we provide an empirically validated watchlist of future invaders.
Shahar Chaikin +4 more
wiley +1 more source

