Results 141 to 150 of about 13,596 (270)
Self‐Cooling Molecular Spin Qudits
A material made of [GdEr] molecular dimers can encode a qudit and perform as a magnetic refrigerant. Microwave resonant pulses coherently manipulate its 16 spin states, while direct demagnetization measurements cool the material and a device down to temperatures below 1 K.
Elías Palacios +12 more
wiley +1 more source
Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
The TAD-pathway for GWAS signals [PDF]
Prokopenko, I, Pervjakova, N
openaire +4 more sources
A three‐tier livestock multi‐omics framework resolves four typical analytical pitfalls. Moving from statistical association through machine learning preprocessing to triple‐modal causal inference, it converts omics results into genomic selection and gene editing strategies to achieve One Health, underpinned by multi‐omics data, multimodal sequencing ...
Jiying Wen +5 more
wiley +1 more source
Étude des « Topologically Associated Domains (TADs) » dans les anomalies du développement
The study of tridimensional organization of chromatin by Hi-C technology, derived from Chromosome Conformation Capture (3C), revealed chromatin domains named Topologically Associated Domains (TADs).
Trimouille, Aurelien
core
Beyond PEG: Emerging Polymer Lipid Alternatives for Lipid Nanoparticle (LNP) Formulations
This review discusses recent advances in PEG‐alternative LNP designs, including non‐PEG polymers, zwitterionic lipids, and polypeptides. It evaluates how surface‐engineering chemistry influences LNP formation and biological behavior, and highlights current limitations and opportunities of PEG‐alternative LNPs.
Zihnil A. I. Mazrad +4 more
wiley +1 more source
NMR Investigation of Water in Mesoporous Silica Materials With Different Surfaces
Narrow pores of mesoporous silica are filled with water in an axial mode, independent of the surface hydrophobicity. The influence of the hydrophilicity of mesoporous silica on wetting with water was investigated by comparing a standard hydrophilic MCM‐41 and a partially hydrophobicized material obtained by trimethylsilylation of MCM‐41.
Yanjing Zhao +3 more
wiley +1 more source
Loss of SUMOylation drives aberrant PRC1 clustering and 3D genome rewiring independent of H3K27me3. [PDF]
Akilli N +8 more
europepmc +1 more source
Transcription and Three‐Dimensional Genome Organization: Cause, Consequence, or Coordination?
Transcription and 3D genome organization influence each other across spatial scales. Large‐scale architecture provides a relatively stable framework, while transcription and shared architectural factors refine local chromatin loops and domain boundaries. Specific long‐range interactions between regulatory elements and distal anchors can override domain‐
Dagyeong Yang, Elissa P. Lei
wiley +1 more source

