Epigenetic Regulation in Cardiovascular Diseases: Mechanisms and Therapeutic Targets
Environmental and lifestyle exposures reshape the cardiovascular epigenome through coordinated regulation of DNA methylation, histone modifications, noncoding RNAs, and RNA methylation (m6A). These multilayered mechanisms drive enhancer‐centered regulatory network remodeling and epigenomic plasticity in cardiovascular diseases, highlighting emerging ...
Wangzheqi Zhang +7 more
wiley +1 more source
Stress distribution and displacement in maxillary anterior teeth during simultaneous intrusion and retraction using a 3D FEA model. [PDF]
Hussain SA +4 more
europepmc +1 more source
Oxidative Stress and DNA Epigenetic Modifications in Cancer: Mechanisms and Targeted Therapeutics
Reactive oxygen species (ROS) modulate DNA methyltransferases (DNMTs), ten‐eleven translocation family proteins (TETs) and their cofactors, reshaping 5‐methylcytosine (5mC)/5‐hydroxymethylcytosine (5hmC)/5‐formylcytosine (5fC) landscapes and gene expression in cancer cells. In turn, epigenetic control of antioxidant and metabolic pathways feeds back on
Xishan Yang +7 more
wiley +1 more source
Retreatment using temporary anchorage device for a patient with relapse after orthognathic surgery: a case report. [PDF]
Aoki N, Tominaga A, Kubo Y, Baba J.
europepmc +1 more source
Chromosome segregation in a minimal bacterial cell driven by SMC protein complexes
Abstract Minimal bacterial cells such as JCVI‐Syn3A provide a powerful system for uncovering the essential mechanisms of chromosome organization and segregation. Lacking canonical systems such as Min and ParABS, JCVI‐Syn3A relies primarily on structural maintenance of chromosomes (SMC) protein complexes for partitioning.
Andrew K. Maytin +2 more
wiley +1 more source
Pitfalls and missing links in current understanding of 4D genomes
Abstract The spatial and temporal organization of the genome—collectively termed the 4D genome—is pivotal for regulating gene expression, maintaining genome stability, and guiding development. The convergence of chromosome conformation capture technologies, super‐resolution microscopy, and single‐cell epigenomics has transformed our understanding of ...
Michael Q. Zhang
wiley +1 more source
Survey of Norwegian orthodontists on the use of temporary anchorage devices. [PDF]
Tostrup IM +4 more
europepmc +1 more source
Single‐walled carbon nanotubes (SWCNTs) are versatile optical nanosensors that can be imaged at the single‐sensor level to map biological processes. To translate such imaging into calibrated measurements, sensor recovery under repeated analyte exposures must be analyzed.
Geffen Rosenberg, Gili Bisker
wiley +1 more source
Road Traffic Anomaly Detection by Human-Attention-Assisted Text-Vision Learning. [PDF]
Chai Y, Silamu W.
europepmc +1 more source
Predictive Models for Postfire Debris Flow Initiation in the Southwest USA
Abstract Postfire debris flows pose a threat to life and infrastructure and significantly contribute to sediment supply in upland channels, thereby impacting water quality, stream habitats, and landscape evolution. Models designed to assess postfire debris‐flow likelihood at the watershed scale in response to design or forecast rainstorms are ...
Ana Isabel Fernandez Sirgo +3 more
wiley +1 more source

