Results 111 to 120 of about 257,409 (278)

The analgesic effect of Curcuma Longa rhizome methanol extract in male rat

open access: yesفصلنامه دانشگاه علوم پزشکی جهرم, 2018
Background: There are several reports on the therapeutic effects of curcuma longa in traditional medicine such as anti inflammatory,  antinocieptive , antioxidant    ,anti carcinogenic and hepatoprotective effects.
arian khani, afsaneh ranjbar
doaj  

Root‐Inspired Microneedle Patch With Interlocked Rigid‐Soft Architecture for High Tissue‐Adaptiveness

open access: yesAdvanced Science, EarlyView.
A root‐inspired microneedle array patch uses lattice‐based mechanical interlocking to unite rigid microneedles with a flexible substrate. The interlocked rigid–soft architecture improves interfacial bonding, supports stable adhesion on curved and wet tissues under dynamic motion, and provides a versatile platform for robust biointerfacing and future ...
Jongchan Lee   +9 more
wiley   +1 more source

Antinociceptive Effect of Promethazine in Mice [PDF]

open access: yesIranian Journal of Basic Medical Sciences, 2009
Objective(s)The present study was undertaken to investigate the nociception activity of promethazine, a tranquillizer devoid of hypnotic activity in mice.Materials and MethodsAntinociception was evaluated, using the acetic acid-induced writhing, tail ...
Amir Farshchi   +4 more
doaj  

Voyage autour de ma chambre

open access: yes
Übers. unter dem Vorw. genannt: Friedr. von Zinck. - Verf. ermittelt in BVB-Verbundkatalog und, anhand des Einheitssachtitels, in BN-Opale plus: Xavier de MaistreEinheitssacht. im Vorw. genanntVorlageform des Erscheinungsvermerks: Basel, bei Samuel Flick
Maistre, Xavier
core   +1 more source

Klotho‐Derived Peptide 1 Protects against Acute Kidney Injury by Directly Targeting Mitochondrial ATAD3A

open access: yesAdvanced Science, EarlyView.
This study uncovers that KP1, a Klotho‐derived peptide, protects the kidney against acute kidney injury, a clinical syndrome with high morbidity and mortality. KP1 enters tubular epithelial cells via endocytosis, directly interacts with the mitochondrial ATAD3A/HIGD2A complex, thereby preventing cytochrome c release, and caspases activation, and ...
Xiaoyao Zhang   +6 more
wiley   +1 more source

Investigations of the Evolved Molecular Basis for Terpenoid Biosynthesis in Marine Sponges

open access: yesAdvanced Science, EarlyView.
Confirming and extending a previous observation in another Bubarida sponge, genomic and functional analyses of A. cavernosa reveal that sponges retain the mevalonate pathway and employ single α‐domain T1TSs and UbiA‐type TSs for terpenoid biosynthesis. The absence of T1TSs clustering with other biosynthetic genes tentatively suggests, based on limited ...
Fangyan Chen   +6 more
wiley   +1 more source

The Mitogen‐Activated Protein Kinase GhNTF3 Modulates the Arbuscular Mycorrhizal Symbiosis‐Immunity Trade‐Off in Cotton by Regulating Salicylic Acid Biosynthesis

open access: yesAdvanced Science, EarlyView.
AM symbiosis induces GhWAK13 to promote fungal colonization. GhNTF3 negatively regulates symbiosis by promoting SA biosynthesis. GhWAK13 sequesters GhNTF3 at the membrane, limiting its nuclear translocation and relieving SA‐mediated suppression. Under Verticillium stress, GhNTF3 enters the nucleus and interacts with GhJAZ6 to activate SA signaling ...
Shuangjie Jia   +10 more
wiley   +1 more source

1,4-dihydropyridine derivatives (oxidized, D3-72 and V-1-53-2) analgesic activity with the Tail Flick method

open access: yes, 2011
Analgētiskās vielas tiek lietotas lai remdētu sāpes. Atkarībā no sāpju intensitātes vai lokalizācijas tiek lietotas dažādas analgētiskas vielas: opiāti, NSPL, ne - opiātu analgētiķi (piem., Flupirtin, Paracetamol).Pirms farmakoloģiskās vielas izmanto ...
Tereņina, Olga
core  

Antinociception versus serum concentration relationships following acute administration of intravenous morphine in male and female Sprague-dawley rats: Differences between the tail flick and hot plate nociceptive tests

open access: yes, 2009
Antinociception versus serum morphine concentration relationships were defined in male and female Sprague-Dawley rats administered single intravenous (i.v.) bolus doses of morphine, using the hot plate (2.1-14 mg/kg) and tail flick tests (1-8 mg/kg)
Edwards, Stephen R.   +2 more
core   +1 more source

An Effector TaCRVP From Tuta Absoluta Oral Secretion Impairs H2O2‐Mediated Plant Defense by Targeting Tomato SlCAT2

open access: yesAdvanced Science, EarlyView.
The Tuta absoluta salivary effector TaCRVP subverts tomato immunity by hijacking host catalase SlCAT2. Through a sophisticated dual mechanism, TaCRVP simultaneously promotes SlCAT2 tetramerization for activation and blocks its SlAdBiL‐mediated degradation for stabilization.
Jianquan Yan   +9 more
wiley   +1 more source

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