Results 191 to 200 of about 64,082 (287)

TPTE, a testis-specific PTEN family member, drives spermatogenesis via PI(4,5)P<sub>2</sub> synthesis. [PDF]

open access: yesCell Death Dis
Chen X   +14 more
europepmc   +1 more source

Pss knockdown in the midgut causes growth retardation in Drosophila similar to that in human LMHD

open access: yesDevelopmental Dynamics, Volume 255, Issue 5, Page 451-463, May 2026.
Abstract Background Phosphatidylserine synthase (PSS), localized in the mitochondrial membrane, synthesizes phosphatidylserine. In humans, mutations in Pss lead to Lenz–Majewski hyperostotic dwarfism, a disorder affecting growth and development. The effects of Pss mutations on the growth of Drosophila melanogaster are not fully known. Hence, this study
Kwan‐Young Kim   +4 more
wiley   +1 more source

Bioinspired STHVO based MPPT control for grid connected photovoltaic water pumping systems. [PDF]

open access: yesSci Rep
Ballouti A   +8 more
europepmc   +1 more source

DNA Copy Number Profiling in Extracellular Vesicles as Clinical Biomarkers of High‐Grade Serous Ovarian Carcinoma

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 5, May 2026.
ABSTRACT Extracellular vesicles (EVs), including exosomes, circulate in body fluids and carry pathological genomic information. High‐grade serous ovarian carcinoma (HGSOC) is the most common subtype of ovarian cancer, characterized predominantly by copy number variations (CNVs).
Ryosuke Uekusa   +17 more
wiley   +1 more source

Differential Trafficking Phenotypes of NPC1 Mutant Proteins Reveal Distinct Cholesterol Accumulation Profiles

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 3, May 2026.
ABSTRACT Niemann‐Pick disease type C (NPC) is a rare autosomal recessive lysosomal storage disorder that affects approximately 1 in 100 000 live births. It is primarily caused by mutations in the NPC1 gene, which disrupts intracellular cholesterol transport and leads to lipid accumulation in late endosomes and lysosomes.
Sanaa Abdelmalek Mahmoud   +3 more
wiley   +1 more source

Calmodulin assists during co‐translational folding of the KV7.2 channel calcium responsive domain

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract In vivo, the majority of nascent protein chains begin folding during translation in order to reach their native structure. While the importance of co‐translational folding has become increasingly clear, the specific mechanisms underlying the coordination between the ribosome, the nascent chain and interacting partners are still uncertain. Here,
Arantza Muguruza‐Montero   +10 more
wiley   +1 more source

SERS‐Based Nano‐ and Microsystems Toward Biomedical Applications

open access: yesSmall, Volume 22, Issue 28, 18 May 2026.
This review provides a current overview of nano‐ and microscale SERS‐based devices, encompassing all aspects from material design to practical applications. We highlight controlled SERS‐active architectures, including patterned substrates, nanorods, microspheres, micromotors, and microneedles, as well as combinations of these microfluidic systems.
Gohar Soufi   +14 more
wiley   +1 more source

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