Results 61 to 70 of about 63,753 (279)
Kinesin‐Induced Buckling Reveals the Limits of Microtubule Self‐Repair
Advanced Science, EarlyView.This study shows that kinesin‐driven buckling induces extensive microtubule lattice damage that often exceeds intrinsic self‐repair and leads to filament failure. While curvature, motor motility, and force individually cause limited damage, their combination overwhelms repair.
Shweta Nandakumar +9 more
wiley +1 more source
Albumin‐Bound STING Agonist Reprograms HSPCs to Antitumor Neutrophils Enhancing CD8+ T Cell Immunity
Advanced Science, EarlyView.This study demonstrates that an albumin‐bound STING agonist (Nano ZSA‐51D) reprograms HSPCs to produce antitumor neutrophils with enhanced MHC I–mediated CD8+ T cell activation, thereby sensitizing tumors to α‐PD1 therapy. These findings highlight a strategy to target early hematopoiesis for shaping neutrophil fate and potentiating cancer immunotherapy.
Jinsong Tao +11 more
wiley +1 more source
Research investigation of helicopter main rotor/tail rotor interaction noise [PDF]
Acoustic measurements were obtained in a Langley 14 x 22 foot Subsonic Wind Tunnel to study the aeroacoustic interaction of 1/5th scale main rotor, tail rotor, and fuselage models.
Fitzgerald, J., Kohlhepp, F.
core +1 more source
Sub-ballistic behavior in quantum systems with L\'evy noise
, 2007 We investigate the quantum walk and the quantum kicked rotor in resonance subjected to noise with a L\'evy waiting time distribution. We find that both systems have a sub-ballistic wave function spreading as shown by a power-law tail of the standard ...
A. Romanelli +5 more
core +1 more source
Advanced Science, EarlyView.CDK5RAP2 associates with the kinesin HSET and forms co‐condensates. HSET motors drive the directional transport of CDK5RAP2 condensates toward microtubule minus ends. During mitosis, HSET self‐assembly further stabilizes clustered centrosomes, thereby enabling pseudo‐bipolar spindle formation in cancer cells with supernumerary centrosomes. Upon mitotic
Po‐Pang Chen +11 more
wiley +1 more source
Научный вестник МГТУ ГА, 2017 For single-rotor helicopters there are special flight modes, when tail rotor (TR) is under significant inductive influence of vortical wake of main rotor (MR).
Yu. M. Ignatkin +3 more
doaj
Experimental study of main rotor tip geometry and tail rotor interactions in hover. Volume 1. Text and figures [PDF]
A model scale hover test was conducted in the Sikorsky Aircraft Model rotor hover Facility to identify and quantify the impact of the tail rotor on the demonstrated advantages of advanced geometry tip configurations.
Balch, D. T., Lombardi, J.
core +1 more source
Programmable RNA N6,2´‐O‐Dimethyladenosine Editing
Advanced Science, EarlyView.ABSTRACT N6,2’‐O‐dimethyladenosine (m6Am) is a prevalent RNA modification located at the first transcribed nucleotide adjacent to the 5′ cap of mRNAs, where it has been implicated in gene regulation. However, the lack of methods for precise, transcript‐specific manipulation of m6Am has limited its functional dissection.
Yang Li +9 more
wiley +1 more source
Acoustic test of a model rotor and tail rotor: Results for the isolated rotors and combined configuration [PDF]
Acoustic data from a model scale main rotor and tail rotor experiment in the NASA Langley 14 by 22 Foot Subsonic Tunnel are presented for the main rotor and trail rotor in isolation and for the two rotors operating together. Results for the isolated main
Burley, C. L. +2 more
core +1 more source
Emerging Molecular Antiferroelectrics: Advances and Prospects
Advanced Science, EarlyView.This review focuses on the current research progress in emerging molecular antiferroelectrics, encompassing their diverse structures, antiferroelectricity‐associated properties, and application exploration, including energy storage, electrocaloric refrigeration, and electrostriction.
Xiaoqi Li +6 more
wiley +1 more source