Results 11 to 20 of about 7,425,562 (280)
Journal of Pharmacological Sciences, 2008 We examined the effect of the novel atypical antipsychotic drug aripiprazole alone or in combination with the selective serotonin reuptake inhibitor fluoxetine in the mouse tail suspension test.
Junzo Kamei +5 more
doaj +6 more sources
Individual differences in response to imipramine in the mouse tail suspension test
Psychopharmacology, 1997 The tail suspension test is a behavioural primary screen for detecting potential antidepressant drugs. In this test, a reduction of duration of immobility after treatment with imipramine is obtained in mice of the NMRI strain but not of the CD1 strain.
Vaugeois, J. M. +3 more
openaire +4 more sources
Synthesis and anti-depressant evaluation of novel pyrazolone derivatives
Bangladesh Journal of Pharmacology, 2016 Diazotization of substituted anilines with NaNO2 and concentrated hydrochloric acid at 0ºC gave the diazonium chlorides. Coupling of substituted aryl diazonium chlorides with ethyl acetoacetate in methanol gave ethyl-2-aryl-hydrazono-3-oxobutyrates (2a-h)
Vijay Kumar Merugumolu +1 more
doaj +4 more sources
The tail suspension test. [PDF]
J Vis Exp, 2012 The tail-suspension test is a mouse behavioral test useful in the screening of potential antidepressant drugs, and assessing of other manipulations that are expected to affect depression related behaviors. Mice are suspended by their tails with tape, in such a position that it cannot escape or hold on to nearby surfaces. During this test, typically six
Can A +5 more
europepmc +4 more sources
Antidepressant-like activity of flunarizine in modified tail suspension test in rats. [PDF]
N Am J Med Sci, 2015 Flunarizine, a Ca(2+) channel blocker, crosses blood brain barrier (BBB), antagonizes calcium influx and interferes with neurotransmitter system. Flunarizine 20 mg/kg exhibited significant antidepressant activity in our previous study using forced swim test (FST) in mice, which was contradictory to the findings of other authors.
Shinde V +4 more
europepmc +4 more sources
Aeroacoustic analysis of main rotor and tail rotor interaction [PDF]
, 2008 The increased restrictions placed on helicopter noise levels over recent decades have encouraged manufacturers to better understand tail rotor noise and its aerodynamic sources.
Fletcher, Timothy M. +5 more
core +9 more sources
, 2023 Background/AimsThe effect and underlying mechanism of microgravity on myocardium still poorly understood. The present study aims to reveal the effect and underlying mechanism of tail-suspension-induced microgravity on myocardium of rats.MethodsTail ...
Chong Xu (536395) +10 more
core +1 more source
, 2023 Background/AimsThe effect and underlying mechanism of microgravity on myocardium still poorly understood. The present study aims to reveal the effect and underlying mechanism of tail-suspension-induced microgravity on myocardium of rats.MethodsTail ...
Chong Xu (536395) +10 more
core +1 more source
Pharmacogenomic Evaluation of the Antidepressant Citalopram in the Mouse Tail Suspension Test [PDF]
Neuropsychopharmacology, 2006 The identification of genetic variants regulating antidepressant response in human patients would allow for more individualized, rational, and successful drug treatments. We have previously identified the BALB/cJ inbred mouse strain as highly responsive to the selective serotonin reuptake inhibitor (SSRI) citalopram in the tail suspension test (TST), a
James J, Crowley +4 more
openaire +2 more sources