Results 101 to 110 of about 1,995 (245)

Characterisation of ten NS2B-NS3 proteases: Paving the way for pan-flavivirus drugs [PDF]

open access: yes
Flaviviruses can cause severe illness in humans. Effective and safe vaccines are available for some species; however, for many flaviviruses disease prevention or specific treatments remain unavailable.
Nitsche, Christoph   +2 more
core   +1 more source

Effectiveness and safety of the tetravalent TAK-003 dengue vaccine: a systematic review.

open access: yesMedicina
In Argentina, the dengue virus has experienced an increase in recent years. This study aims to conduct a systematic review to evaluate the effectiveness and safety of the TAK-003 tetravalent dengue vaccine in this context. A systematic review of randomized controlled trials comparing the effectiveness and safety of the vaccine with placebo in the ...
Agustín, Bengolea   +5 more
openaire   +1 more source

Depletion of p75NTR in Schwann Cells Driven by Inflammation Mediates Cutaneous Pain in Psoriasis

open access: yesAdvanced Science, EarlyView.
Psoriasis‐like inflammation induces proliferation and molecular remodeling of cutaneous Schwann cells, marked by reduced p75NTR and increased NGF expression. IL‐17A promotes this process, whereas Schwann cell‐specific p75NTR overexpression alleviates cutaneous pain in vivo.
Yibo Wang   +9 more
wiley   +1 more source

Polymorphic Superparaelectric Engineering Boosting Energy Storage Capacity in BaTiO3‐Based Ceramics

open access: yesAdvanced Science, EarlyView.
Herein, Ca2+ incorporation promotes the coexistence of CaTiO3‐/BaTiO3‐derived paraferroelectric states, stabilizing cubic‐orthorhombic‐tetragonal polymorphic superparaelectric phases. This minimizes polarization energy barriers, facilitating full polarization saturation without compromising efficiency.
Pan Liu   +9 more
wiley   +1 more source

Updates on Dengue Vaccines [PDF]

open access: yes
01-Dengue-chen-508 ...

core  

Evaluating The Effects of Chitin and Its Analogues with Improved Solubility on Human Hexokinase Isoform 2 for Dengue Treatment via Virtual Screening Analyses [PDF]

open access: yes
. Dengue fever, a vector-borne disease caused by dengue virus (DENV) is currently endemic in over 100 countries. Despite being pronounced as one of the WHO’s ten threats to global health in 2019, there are currently no antiviral therapies for dengue ...
Abdul Wahab, Mohd Firdaus   +4 more
core   +2 more sources

Electrochemical Hofmann Rearrangement for Modular Synthesis of Unsymmetrical Ureas and Late‐Stage Modification of Drugs

open access: yesAdvanced Science, EarlyView.
An electrochemical Hofmann rearrangement of amide involving amine or other amide nucleophiles has been developed. The use of NaI guarantees the feasibility and compatibility of the electrosynthesis protocol, which enables highly chemoselective synthesis of unsymmetrical N‐acylureas from two different amides, as well as the production of unsymmetrical ...
Xue‐Qing Mou   +9 more
wiley   +1 more source

ACIP Dengue Vaccines Work Group [PDF]

open access: yes
01-Dengue-Chen-508 ...

core  

Retina‐Inspired Bi‐Based Terahertz Photonic Neuromorphic Devices

open access: yesAdvanced Science, EarlyView.
Combined with effective band alignment and substrate engineering, bismuth materials are introduced to form terahertz photonic bio‐inspired devices with picosecond short‐term plasticity to enable multi‐scene visual perception. Thus obtained hardware through the terahertz optical neural network (THz‐ONN) demonstrates high recognition accuracy, providing ...
Pujing Zhang   +14 more
wiley   +1 more source

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