Results 21 to 30 of about 3,173 (204)

CARACTERIZAÇÃO DAS MUTAÇÕES DE BETA TALASSEMIA EM PESSOAS COM DOENÇA FALCIFORME (HB S/BETA TALASSEMIA): EXPERIÊNCIA DE CINCO ANOS DE UM CENTRO DE REFERÊNCIA

Hematology, Transfusion and Cell Therapy, 2023
Objetivos: Realizar a caracterização de mutações de beta talassemia em pessoas com doença falciforme (Hb S/Beta-talassemia). Material e métodos: No período de cinco anos, 29 amostras de pessoas com diagnóstico molecular inconclusivo para a doença ...
JJR Silva, BBV Marques, IS Dias, ACM Berti, VS Ramos, AC Purificação, TRB Azevedo, T Amorim, DGH Silva, E Belin-Junior   +9 more
doaj   +1 more source

Long-term outcomes of avascular necrosis in sickle cell disease using joint-specific patient-reported outcome measures: Results from a multicentre study. [PDF]

Br J Haematol
Summary Avascular necrosis (AVN) is a prevalent and progressive complication in young patients with sickle cell disease (SCD), but no study evaluated the long‐term subjective and objective outcome measures. Oxford hip score (OHS) and Oxford shoulder scores (OSS) are validated joint‐specific patient‐reported outcome measures (PROMs). In this prospective
Casale M, Toro G, Porcelli F, Quota A, Rosso R, Spadola V, Arcioni F, Campisi S, Roberti D, Perrotta S.   +9 more
europepmc   +2 more sources

IN UTERO HAEMATOPOIETIC STEM CELL TRANSPLANTATION (IUHSCT)

Mediterranean Journal of Hematology and Infectious Diseases, 2009
In utero haematopoietic stem cell transplantation (IUHSCT) is a non-myeloablative approach for the prenatal treatment of genetic disorders. However, in target disorders, where there is not a selective advantage for donor cells, a useful donor-cell ...
Maria Concetta Renda, Aurelio Maggio
doaj   +1 more source

Differential diagnosis of iron deficiency [PDF]

, 2010
Iron deficiency is considered to be the commonest hematological pathology in humans. Thus, the essential steps in an adequate approach of iron deficiency include: the proper identification of its causes and the differentiation between iron deficiency and
Figueiredo, Maria Stella, Vicari, Perla
core   +1 more source

Bronquite plástica em criança com talassemia alfa Plastic bronchitis in a child with thalassemia alpha

Jornal de Pediatria, 2005
OBJETIVO: A bronquite plástica é uma doença infreqüente na criança, sendo caracterizada por moldes ou cilindros mucofibrinosos na árvore traqueobrônquica.
Tiago N. Veras, Gustavo M. Lannes, Jefferson P. Piva, Renato T. Stein, Marcus H. Jones, Vinicius D. Silva, Pedro Celiny R. Garcia, Paulo M. C. Pitrez   +7 more
doaj   +1 more source

Long-term treatment with deferiprone enhances left ventricular ejection function when compared to deferoxamine in patients with thalassemia major [PDF]

, 2013
Transfusion and iron chelation treatment have significantly reduced morbidity and improved survival of patients with thalassemia major. However, cardiac disease continues to be the most common cause of death.
Barone, R, Calvaruso, G, Campisi, S, Capra, M, Caruso, V, Casale, M, Ciancio, A, Cianciulli, P, Cuccia, L, D'Ascola, G, Filosa, A, Gagliardotto, F, Gerardi, C, Maggio, A., Pitrolo, L, Prossomariti, L, Rigano, P, Rizzo, M, VITRANO, Angela   +18 more
core   +1 more source

Terapia quelante oral com deferiprona em pacientes com sobrecarga de ferro Oral iron chelator therapy with deferiprone in patients with overloaded iron

Revista Brasileira de Hematologia e Hemoterapia, 2003
Apesar da introdução da quelação parenteral de ferro com desferoxamina há mais de trinta anos, 50% dos pacientes com talassemia major morrem antes dos 35 anos de idade, predominantemente por insuficiência cardíaca secundária a sobrecarga de ferro. Embora
Antonio Fabron Jr, Fernando Tricta
doaj   +1 more source

Serial echocardiographic left ventricular ejection fraction measurements: a tool for detecting thalassemia major patients at risk of cardiac death [PDF]

, 2013
Cardiac damage remains a major cause of mortality among patients with thalassemia major. The detection of a lower cardiac magnetic resonance T2* (CMR-T2*) signal has been suggested as a powerful predictor of the subsequent development of heart failure ...
Angastiniotis, M, Barone, R, Calvaruso, G, Campisi, S, Capra, M, Caruso, V, Chattipakorn, N., Cianciulli, P, Cuccia, L, Elefteriou, A, Filosa, A, Gerardi, C, Hamzac, H, Maggio, A, Mancuso, L, Phrommintikul, A, Pitrolo, L, Prossomariti, L, Rigano, P, Telfer, P, VITRANO, Angela, Walkerc, JM   +21 more
core   +1 more source

Brazilian consensus meeting on stem cell transplantation: hemoglobinopathies comittee [PDF]

, 2010
Os distúrbios hereditários das hemoglobinas são as doenças genéticas mais frequentes do homem e mais difundidas no mundo, abrangendo sobretudo continentes como África, Américas, Europa e extensas regiões da Ásia.
ANGULO, Ivan, BARROS, George M. N., CANÇADO, Rodolfo D., MACHADO, Clarisse L., PIERONI, Fabiano, SALVINO, Marco Aurélio, SIMÕES, Belinda P., VOLTARELLI, Julio Cesar   +7 more
core   +1 more source

Nonpeghylated liposomal doxorubicin combination regimen (R‐COMP) for the treatment of lymphoma patients with advanced age or cardiac comorbidity

Hematological Oncology, Volume 38, Issue 4, Page 478-486, October 2020., 2020
Abstract Doxorubicin is the most effective single agent in the treatment of non‐Hodgkin's lymphoma (NHL). Its use is limited because of the cardiac toxicity primarily in elderly patients (pts) and in pts with history of cardiac disease. Liposomal doxorubicin has been proven to reduce cardiotoxicity.
Luigi Rigacci, Ombretta Annibali, Sofya Kovalchuk, Elisabetta Bonifacio, Francesca Pregnolato, Francesco Angrilli, Umberto Vitolo, Samantha Pozzi, Serena Broggi, Stefano Luminari, Francesco Merli, Michele Spina, Silvia Bolis, Gloria Margiotta‐Casaluci, Rosario Scalzulli, Christina Cox, Angela Maria Mamusa, Armando Santoro, Pier Luigi Zinzani, Samantha Ferrari, Guido Gini, Maria Luigia Vigliotti, Antonino Mulè, Leonardo Flenghi, On behalf ofFondazione Italiana Linfomi (FIL)   +24 more
wiley   +1 more source