Results 31 to 40 of about 703,333 (283)

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

The influence of talent management on organisational performance in Bosnia & Herzegovina as a developing country

Management : Journal of Contemporary Management Issues, 2021
In today's globalized, fast-changeable, and digitalized market, companies strongly need and seek talents, who, besides basic skills, possess higher levels, as well as the optimal mix of different competencies and qualifications.
Elvir Čizmić, Azra Ahmić
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Slow Shift—Developing Provisions for Talented Students in Scandinavian Higher Education

Education Sciences, 2016
For decades, Scandinavian culture effectively prohibited the development of special provisions for talented students in higher education. However, in recent years, a cultural shift has gradually made more room for excellence and talent development in the
Marca Wolfensberger, Maarten Hogenstijn
doaj   +1 more source

Identifying the Components of the Talent Management of faculty Members in Universities of Medical Sciences: A Meta-synthetic Study [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2021
Introduction: Talent management, especially in higher education, is important due to the main role it can play in tackling the global challenges and development of different countries. This study endeavored to identify the components of talent management
ٍElham keykha, Ahmad keykha
doaj  

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Spatial Distribution and Influencing Factors of High-Tech Talents at Different Stages in China

Redai dili
As China transitions to high-quality economic development, the innovation-driven growth model places increasing demand on the high-tech industry, highlighting the critical role of high-tech talent in enhancing regional competitiveness.
Yang Yunjia, Cui Can, Wang Qiang, Chen Nanxi   +3 more
doaj   +1 more source

The US golf academy system and the twenty first century talent tourists! Future lines of research to understand this new golfing talent pathway [PDF]

, 2017
This paper addresses the rapid growth, popularity, and structure of US Golf Academies. Specifically, we highlight a phenomenon from a non-US golfing community’s perspective; namely, that of the “talent tourist” (i.e., youth golfer) seeking to develop ...
Carson, H.J., Collins, D.,, Grecic, D., Ryan, B.   +3 more
core   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Introducing a Talent Management Model based on Grounded theory (Case Study: Telecom Operator) [PDF]

پژوهش‌های مدیریت عمومی, 2017
Extended Abstract Changing economic and technological paradigms, causes very significant issues in different industries, especially technology-laden ones, like telecom.
Ariyan Gholipor, Nayere Eftekhar
doaj   +1 more source