Results 31 to 40 of about 120,245 (308)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizational Unlearning: A Bibliometric Study and Visualization Analysis Via CiteSpace

open access: yesSAGE Open
Coping with evolution and the changes it brings to the workplace remains a major concern for organizational leaders. This study explores the hotspots, trends, and future directions of the field of organizational unlearning to complement the extant ...
Jiang Chen   +2 more
doaj   +1 more source

Strategy in talent systems: Top-down and bottom-up approaches

open access: yesFrontiers in Sports and Active Living, 2022
Building on a large volume of recent research in talent identification and development, this paper future directions for research and practice. We suggest that strategic coherence become a greater point of emphasis in both, with the Performance, Outcome ...
Jamie Taylor   +4 more
doaj   +1 more source

An investigation into talent identification and development in English Netball [PDF]

open access: yes, 2009
The Institute of Sport and Leisure Policy (ISLP) at Loughborough University was pleased to respond to a request by Cathy Partridge, Regional Talent Officer for the East Midlands, and Kelly Parkyn, Talent Manager for England Netball, to investigate talent
Robinson, Leigh, Downward, Paul
core  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

A Philosophical Approach to Talent Development

open access: yesRoeper Review, 2023
High ability and talent development literature present different and sometimes competing or contradictory goals for talent development. One side emphasizes that talents should be developed to enable individuals with high abilities to make societal contributions, while the other side focuses on the individual?s personal life goals.
Anne Van de Vijver, Sven Mathijssen
openaire   +4 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

open access: yesFEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara   +3 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Spatial Distribution and Influencing Factors of High-Tech Talents at Different Stages in China

open access: yesRedai dili
As China transitions to high-quality economic development, the innovation-driven growth model places increasing demand on the high-tech industry, highlighting the critical role of high-tech talent in enhancing regional competitiveness.
Yang Yunjia   +3 more
doaj   +1 more source

What establishes an excellent nurse? A focus group and Delphi panel approach

open access: yesBMC Nursing, 2017
Background Over the past few years, the complexity of the health care system in which nurses are required to practice has increased considerably, magnifying the need for excellent professionals with a specific set of knowledge, skills and attitudes ...
Wolter Paans   +3 more
doaj   +1 more source

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