Results 71 to 80 of about 703,333 (283)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Talent Management Implementation at an Open Distance E-Learning Higher Educational Institution: The Views of Senior Line Managers

International Review of Research in Open and Distributed Learning, 2017
The war for talent remains a challenge that many organisations face but more so for distance education institutions to deliver on its mandate to provide effective online academic offerings.
Barney Erasmus, Lynette Naidoo, Pierre Joubert   +2 more
doaj   +1 more source

Sectors Expansion, Allocation of Talent and Adverse Selection in Development [PDF]

This paper proposes a theory in which informational failures hindering an efficient operation of the economy are solved over the course development.
Esteban Jaimovich
core  

Coach development through collaborative action research: enhancing the learning environment within a national talent development system [PDF]

, 2016
Motivation to learn is an essential factor of talent being realised , which throws into light the essential role that the motivational climate plays in developing talent. Through collaborative action research, the aim of this study was to develop coaches’
Ahlberg M., Alvarez S. A., Ames C., Bailey R., Carr W., Cecchini J. A., Collins D. J., Conde C., Cushion C. J., Davids K. W., DeWalt K. M., Duda J. L., Epstein J., Evans J., Farrow D., Greenwood D., Hassan M. F. H., Herr K., Kemmis S., Lewin K., Light R., Martindale R., Maykut P. S., McNiff J., McNiff J., Mertler C. A., Morgan K., Morgan K., Morgan K., Nash C., Oja S. N., Pill S., Sparkes A. C., Trenberth L., Tsai S. D., Woodman L.   +35 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Predictive validity of admission tests and educational attainment on preclinical academic performance – a multisite study

BMC Medical Education
Background Educational attainment and admission tests have a longstanding history in the selection of medical students and are often used simultaneously in selection processes.
Malvin Jaehn, Johanna Hissbach, Madita Frickhoeffer, Daniel Weppert, Alexander Zimmerhofer, Wolfgang Hampe, Martina Kadmon, Nicolas Becker   +7 more
doaj   +1 more source

Global Talentship: Toward a Decision Science Connecting Talent to Global Strategic Success [PDF]

, 2002
It is widely accepted that global competitive advantage frequently requires managing such complex situations that traditional organization and job structures are simply insufficient.
Boudreau, John W., Dowling, Peter J., Ramstad, Peter M.   +2 more
core   +2 more sources

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Problematising the ‘war for talent’: using Sen’s Capability Approach as a new framework for thinking about talent management [PDF]

This article uses Sen’s Capability Approach primarily to conceptualise an evaluative framework for organizational talent management strategies but also to suggest a more human basis for identifying and recognising talent.
Downs, Yvonne, Swailes, Stephen
core  

Managing and mobilising talent in Malaysia: issues, challenges and policy implications for Malaysian universities [PDF]

, 2016
The future of Malaysia as a high-income and competitive nation largely depends on its pool of highly skilled human capital. Hence, the issue of human capital development has taken centre stage in numerous reform agendas of Malaysia.
Azman, Norzaini, Sirat, Morshidi
core   +1 more source