Results 111 to 120 of about 90,488 (249)

FOXA2 as a SETD1A-Regulated Driver of Tamoxifen Resistance in Breast Cancer. [PDF]

Oncol Res
Kim MR, Lee JR, Zhang X, Jeong KW.
europepmc   +1 more source

What Happens After Menopause (WHAM)? A Progress Report of a Prospective Controlled Study of Women After Pre‐Menopausal Risk‐Reducing Bilateral Salpingo‐Oophorectomy

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Surgical menopause, the removal of both ovaries prior to natural menopause, may impact short‐and long‐term physical and emotional health. An increasingly common cause of surgical menopause is risk‐reducing salpingo‐oophorectomy (RRSO) in those at high inherited risk of ovarian cancer.
Sarah A. L. Price, Pauline M. Maki, Samar R. El Khoudary, Alison Brand, Rakibul M. Islam, Susan M. Domchek, Hadine Joffe, Gita D. Mishra, Katrina M. Moss, Fiona C. Baker, Sabine Braat, John D. Wark, Martha Hickey   +12 more
wiley   +1 more source

Synergistic combinatorial anticancer potential of Tamoxifen with Naringin and Diosmetin in MCF-7 breast cancer cells and their liposomal delivery. [PDF]

Sci Rep
Uniyal P, Das Pramanik S, Pandey S, Shukla P, Roy P, Parashar D, Gupta S, Rawat R, Gaurav A, Lee VS.   +9 more
europepmc   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel, Aureliane Pierret, Edouard G. Mills, Alexander N. Comninos, Waljit S. Dhillo, Ali Abbara   +5 more
wiley   +1 more source

Steroid receptor coactivator 3-deficient regulatory T cells eradicate multiple solid tumors in syngeneic mouse models. [PDF]

Oncoimmunology
Sung N, Kim E, Gilad Y, Park Y, Dean AM, Xia Y, Xu J, Dacso CC, Lonard DM, Han SJ.   +9 more
europepmc   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source

Outcomes for Patients With Micro‐Invasive or Small HER2+ Breast Cancer in Northern Sydney Local Health District

Asia-Pacific Journal of Clinical Oncology, EarlyView.
This retrospective study of patients with small, node‐negative HER2+ breast cancer found favorable 5‐year invasive disease‐free survival rates—93% for pT1mic/a disease and 100% for pT1b disease. Trastuzumab was administered to 66% of patients and was associated with larger tumor size and higher histologic grade.
Yuanyuan Xue, Katrina Moore, Tricia Saurine, David Chan, Lina Pugliano, Connie Diakos   +5 more
wiley   +1 more source

Wnt/β -catenin signalling shapes macrophage behaviour during injury and repair in the mouse submandibular gland. [PDF]

Sci Rep
Ahmed A, Sachdeva S, Whawell S, Miletich I.   +3 more
europepmc   +1 more source

Sensitizer‐Induced Basophils Accelerate Skin Re‐Epithelialization via IL‐4/IL‐13‐Mediated Macrophage Polarization

Allergy, EarlyView.
Oxazolone exposure drives rapid basophil recruitment to wounded skin, accelerating re‐epithelialization, angiogenesis, and tissue regeneration. Basophils are the dominant early source of IL‐4 and IL‐13 in the wound microenvironment. Basophil‐derived IL‐4/IL‐13 promote macrophage polarization toward a pro‐repair M2 phenotype, enabling efficient wound ...
Yufei Zhang, Xueting Peng, Kaixuan Ren, Shiran Kang, Zihan Xue, Yazhuo Li, Zhu Yan, Rongfang Feng, Min Gao, Qin Chen, Xiaoying Ning, Fan Bai, Liesu Meng, Yumin Xia, Yale Liu   +14 more
wiley   +1 more source

Development and characterization of an inducible Tensin1 deficient transgenic murine model. [PDF]

Sci Rep
Bernau K, Holbert K, McDermott IS, Rahar B, Coulter KW, Osterhaus MA, Harr TJ, Gehl C, Oler AT, Huffman C, Gray B, Langel TS, Chan KM, Forati A, BonDurant SS, Berres ME, Krentz KJ, Rubinstein CD, Mejia AF, Sandbo N.   +19 more
europepmc   +1 more source