Results 151 to 160 of about 90,488 (249)

Venlafaxine reduces hot flashes in hormone receptor-positive breast cancer patients receiving tamoxifen: a prospective single-arm, open-label trial. [PDF]

Breast Cancer
Sato R, Kamohara R, Matsuo T, Sawa A, Okazaki M, Hashimoto S, Iguchi-Manaka A, Hara H, Doki K, Mukai Y, Homma M, Ishii R, Shimada K, Bando H.   +13 more
europepmc   +1 more source

MASLD Is Associated With Decreased General Health Perception, Quality of Life and Work Productivity in a Low Fibrosis Population

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background Data on quality of life in a low fibrosis prevalence metabolic dysfunction‐associated steatotic liver disease (MASLD) cohort are scarce, as previous research has focused on advanced fibrosis and cirrhosis. This study examined the association between steatosis and general and mental health, as well as productivity in patients in ...
L. J. M. Heyens, C. Van Steenkiste, M. Struyve, S. M. Francque, G. H. Koek, G. Robaeys, the MASLD Research Group, Y. Kockaerts, I. Lowyck, K. Stinkens, H. Van Leeuwen‐Wintjens, L. Vernijns, J. Germaux, T. Meyers, J. Gyselaers, S. Pietermans, R. Bollen, A. Robaeys, C. Gilio, R. Remmen, J. Muris, M. Uitterhoeve‐Prins, M. Bremers, L. van Bokhoven, K. de Munck, E. Rubens, K. Joris   +26 more
wiley   +1 more source

ZNF384‐Driven Fibulin‐1 Exacerbates Vascular Stiffness via TGF‐β/Smad3‐Mediated Senescence and Fibrosis

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
This article elucidates the regulatory molecular mechanisms of Fibulin‐1 (Fbln1) in vascular stiffness and explores potential therapeutic interventions. Zinc Finger Protein 384 (ZNF384) binds to the Fbln1 promoter, driving its expression. Fbln1 activates the TGF‐β/Smad3 axis, promoting vascular smooth muscle cell (VSMC) senescence and collagen ...
Dan Yan, Tianyi ji, Xiaolu Liang, Mandi Luo, Yi Huang, Pengcheng Luo, Zhen Yang, Le Zhang, Tao Li, Yong Ping Bai, Cuntai Zhang, Lei Ruan   +11 more
wiley   +1 more source

Impact of the interruption of tamoxifen for pregnancy on the recurrence and survival outcomes among young women with breast cancer. [PDF]

Breast
Cha CD, Jeon S, Keum J, Pak SJ, Park B, Chung MS.   +5 more
europepmc   +1 more source

Ketone Body Supplementation Exerts Renoprotective Effects Against Adenine‐Induced Kidney Injury via OXCT1‐Mediated Ketolysis in Mice

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
1,3‐Butanediol is a ketone body precursor that is directly converted into the ketone bodies, β‐hydroxybutyrate (BHB), in the liver. When renal ketolysis, regulated by 3‐oxoacid CoA‐transferase 1 (OXCT1), is preserved, BHB supplementation exerts renoprotective effects.
Shoji Omachi, Sho Sugahara, Junya Horiguchi, Mako Yasuda‐Yamahara, Shogo Kuwagata, Kosuke Yamahara, Yuki Tanaka‐Sasaki, Shogo Ida, Tetsuro Kusaba, Benjamin D. Humphreys, Kenji Kufukihara, Jin Nakahara, Masami Chin‐Kanasaki, Shinji Kume   +13 more
wiley   +1 more source

Five-Year Incidence of Urinary Incontinence in 68,066 Breast Cancer Patients Followed in Gynecology Practices in Germany. [PDF]

Diseases
Becker LI, Kostev K, Kalder M.
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, Volume 20, Issue 3, Page 753-778, March 2026.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Endocrine Therapy for Endometrial Carcinoma: Current Evidence, Resistance Mechanisms, and Biomarker-Driven Patient Selection. [PDF]

Curr Oncol
Yamanaka T, Yoshida H, Shimoi T, Sudo K, Yonemori K.   +4 more
europepmc   +1 more source

Sex Hormones Associate With Amyotrophic Lateral Sclerosis Risk and Survival

Annals of Clinical and Translational Neurology, Volume 13, Issue 3, Page 612-617, March 2026.
ABSTRACT Amyotrophic lateral sclerosis (ALS) risk differs by sex and age, implicating sex hormones as potential modifiers. This study examined plasma levels of biologically active sex hormones and their association with ALS odds and survival in cases (females n = 131, males n = 189) and controls (females n = 138, males n = 150) from the University of ...
Stephen A. Goutman, David G. Stouffer, Dae‐Gyu Jang, Jihyun Park, Benjamin J. Murdock, Richard J. Auchus   +5 more
wiley   +1 more source

Adjuvant ovarian function suppression and aromatase inhibitors in premenopausal patients with hormone receptor and HER2 positive breast cancer, by timing of chemotherapy and trastuzumab and response to neoadjuvant therapy. [PDF]

Breast
Shai A, Wildiers H, Venieri C, Pogoda K, Linderholm B, Lambertini M, Matos L, De Maio D'Esposito E, Hajjaji N, Matos E, González Cortijo L, Fotia G, Fortuna A, Sella T, Gouveia H, Rosset L, Constantinidou A, Angeli E, Cicin I, Tjan-Heijnen V, Ruyssers N, Demasure S, Abu Remilah A, Huygh G, Paluch-Shimon S, Chiappe E, Shirron N, Neven P, Artac M, Kilictas B, Baranseh J, Vicente-Rubio E, Atci M, Amato O, van Duijnhoven F.   +34 more
europepmc   +1 more source