Results 221 to 230 of about 113,809 (305)

Oncofertility in the Age of HER2 Blockade, Immunotherapy, PARP inhibitors, CDK4/6 inhibitors and Endocrine Treatment: Unanswered Questions in Breast Cancer. [PDF]

Curr Treat Options Oncol
Weiner-Gorzel K, McSorley L, Walshe JM.
europepmc   +1 more source

An Activity‐Dependent NEPAS–PTX3 Axis Links Neurovascular and Myelin Deficits to Cognitive Impairment

Advanced Science, Volume 13, Issue 37, 3 July 2026.
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu, Zifei Chen, Bingmei Sun, Jiale Gao, Jiale Xu, Xiaochun Guo, Fenfei Gao, Zhongsi Wang, Jie Wu, Xiaoyu Ji, Peipei Liu, Bing Huang   +11 more
wiley   +1 more source

Kat5 cKO mouse replicates biological domain signatures associated with Alzheimer's disease

Alzheimer's &Dementia, Volume 22, Issue 7, July 2026.
Abstract INTRODUCTION Alzheimer's disease (AD) can be caused by autosomal‐dominant familial Alzheimer's disease (FAD) mutations in amyloid precursor protein (APP) or presenilin‐1 and 2, which form an enzyme substrate complex. KAT5 binds to the APP intracellular domain.
Greg A Cary, Jessica E. Young, Shannon E. Rose, Harald Frankowski, Heather Wilkins, Sai Sruthi Amirtha Ganesh, Julia Draper, Martin Darvas, Mark Bothwell, Suman Jayadev, Aquene N. Reid, Anna Greenwood, Allan I. Levey, Karina Leal, Gregory W. Carter, Jesse C. Wiley   +15 more
wiley   +1 more source

Comparing Ovulation Outcomes of Letrozole-Tamoxifen-Estradiolwith and without Vitamin E in Infertile Women with PolycysticOvary Syndrome: A Double-Blind, Randomized Clinical Trial. [PDF]

Int J Fertil Steril
Rasekh Jahromi A, Sharifi N, Karimi Javad M, Rahmanian V.   +3 more
europepmc   +1 more source

Cervical Metastasis From Primary Breast Carcinoma: A Case Report and Review of Extragenital Tumors Involving the Uterine Cervix

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Cervical metastases from breast carcinoma should be considered in the differential diagnosis of uterine lesions in patients with prior breast cancer. Re‐biopsy is essential to detect receptor discordance (ER/PR up to 29%) and guide therapy. GCDFP‐15, mammaglobin, and GATA3 confirm mammary origin.
Mario Assenza, Adele Zappalà, Armando Nallbani, Jacopo Wabersich   +3 more
wiley   +1 more source

Mortality prediction with adjuvant tamoxifen in breast cancer: Machine learning-integrated explainable artificial intelligence and Bayesian model results. [PDF]

ADMET DMPK
Sridharan K, Sivaramakrishnan G.
europepmc   +1 more source

Advanced Uterine Carcinosarcoma With Fatal Suspected Pulmonary Embolism in a Resource‐Limited Setting: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Uterine carcinosarcoma (UCS), also known as malignant mixed Müllerian tumor (MMMT), is a biphasic neoplasm characterized by the presence of carcinomatous (epithelial) and sarcomatous (stromal tissue) elements. It frequently presents at an advanced stage and can mimic primary ovarian carcinoma on clinical and radiological evaluation ...
John Lugata, Onesmo Mrosso, Tecla Lyamuya, Jasmine E. Arrington, Elizabeth Skinner, Bariki Mchome, Eusebious Maro, Alex Mremi   +7 more
wiley   +1 more source

Dual recombinases-mediated genetic tracing reveals no postnatal neo-oogenesis in mice. [PDF]

iScience
Xie H, Zhou B, Zheng P.
europepmc   +1 more source

The Challenge of Determining the Etiology of Encephalopathy in an Elderly Patient

Clinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Encephalopathy is a heterogeneous clinical syndrome with numerous neurological and systemic etiologies. We report the case of a 67‐year‐old man, a chronic ethanol consumer, admitted with a one‐week history of confusional syndrome. Initial laboratory tests revealed severe hypercalcemia, acute kidney injury, mild anemia, and hyperproteinemia ...
Vlad Alexandru Ionescu, Gina Gheorghe, Roxana‐Manuela Vasile, Claudia‐Lucia Ionescu, Mihaela Bazac, Viorica Ileana Bumbea, Alina Valentina Dobrota, Ioana‐Alexandra Baban, Alexandru Barbu, Camelia Cristina Diaconu   +9 more
wiley   +1 more source

Reconsidering the Interpretation of "Recurrence-Free Survival" After Mastectomy for DCIS. Comment on Sae-sim et al. Tamoxifen Reduces Breast Cancer Recurrence in Women with DCIS Who Underwent Mastectomy. <i>Curr. Oncol.</i> 2026, <i>33</i>, 89. [PDF]

Curr Oncol
Venkataraman J, Mokbel K.
europepmc   +1 more source