Results 11 to 20 of about 612,525 (237)
MLL Partial Tandem Duplication [PDF]
Definitions, 2020 A chromosomal rearrangement where exons 5 through 11 or 5 through 12 of the MLL gene are duplicated and inserted upstream of exon 4 of the gene. This duplication results in transcripts and proteins that have the N-terminal region, which contains the AT ...
semanticscholar +2 more sources
FLT3 Internal Tandem Duplication [PDF]
Definitions, 2020 A genetic abnormality that arises from duplications of the juxtamembrane portion of the gene and results in constitutive activation of the FLT3 receptor tyrosine kinase protein in early hematopoietic progenitor cells.
semanticscholar +2 more sources
Detecting long tandem duplications in genomic sequences [PDF]
BMC Bioinformatics, 2012 Background Detecting duplication segments within completely sequenced genomes provides valuable information to address genome evolution and in particular the important question of the emergence of novel functions.
Audemard Eric +2 more
doaj +6 more sources
The Tandem Duplication Distance Is NP-Hard [PDF]
, 2019 In computational biology, tandem duplication is an important biological phenomenon which can occur either at the genome or at the DNA level. A tandem duplication takes a copy of a genome segment and inserts it right after the segment - this can be ...
Lafond, Manuel, Zhu, Binhai, Zou, Peng
core +5 more sources
The Combinatorics of Tandem Duplication [PDF]
Discrete Applied Mathematics, 2015 Tandem duplication is an evolutionary process whereby a segment of DNA is replicated and proximally inserted. The different configurations that can arise from this process give rise to some interesting combinatorial questions.
Greenman, C +2 more
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Gene duplication and evolution in recurring polyploidization–diploidization cycles in plants
Genome Biology, 2019 Background The sharp increase of plant genome and transcriptome data provide valuable resources to investigate evolutionary consequences of gene duplication in a range of taxa, and unravel common principles underlying duplicate gene retention. Results We
Xin Qiao +7 more
doaj +2 more sources
Capacity and Expressiveness of Genomic Tandem Duplication [PDF]
2015 IEEE International Symposium on Information Theory (ISIT), 2015 The majority of the human genome consists of repeated sequences. An important type of repeated sequences common in the human genome are tandem repeats, where identical copies appear next to each other.
Siddhartha Jain +2 more
semanticscholar +7 more sources
Estimation of duplication history under a stochastic model for tandem repeats
BMC Bioinformatics, 2019 Background Tandem repeat sequences are common in the genomes of many organisms and are known to cause important phenomena such as gene silencing and rapid morphological changes. Due to the presence of multiple copies of the same pattern in tandem repeats
Farzad Farnoud +2 more
doaj +2 more sources
EqualTDRL: illustrating equivalent tandem duplication random loss rearrangements [PDF]
BMC Bioinformatics, 2018 Background To study the differences between two unichromosomal circular genomes, e.g., mitochondrial genomes, under the tandem duplication random loss (TDRL) rearrangement it is important to consider the whole set of potential TDRL rearrangement events ...
Tom Hartmann +2 more
doaj +3 more sources
Improved inference of tandem domain duplications [PDF]
Bioinformatics, 2021 Abstract Motivation Protein domain duplications are a major contributor to the functional diversification of protein families. These duplications can occur one at a time through single domain duplications, or as tandem duplications where several consecutive domains are duplicated together as part of a
Aluru, Chaitanya, Singh, Mona
openaire +2 more sources