Results 91 to 100 of about 545,606 (302)

Tandem repeat copy-number variation in protein-coding regions of human genes [PDF]

, 2005
BACKGROUND: Tandem repeat variation in protein-coding regions will alter protein length and may introduce frameshifts. Tandem repeat variants are associated with variation in pathogenicity in bacteria and with human disease.
O'Dushlaine, Colm T., Edwards, Richard, Park, Stephen D., Richard J Edwards, Colm T O'Dushlaine, Denis C Shields, Shields, Denis C., Stephen D Park   +7 more
core   +1 more source

Engineered Nanoplatforms Targeting Activated Hepatic Stellate Cells for Liver Fibrosis Therapy via TGF‐β Axis Inhibition and Ferroptosis Induction

Advanced Healthcare Materials, EarlyView.
FeS‐VA@lanifibranor (FVL), an activated hepatic stellate cell (aHSC)‐targeted nanoplatform comprising vitamin A‐functionalized two‐dimensional iron sulfide nanosheets and lanifibranor, is engineered for precision therapy of liver fibrosis. FVL suppresses the TGF‐β signaling pathway by inhibiting SMAD2/3 phosphorylation and induces ferroptosis in aHSCs,
Yinuo Yang, Mengyao Mu, Ke Ren, Hui Liu, Pengju Ma, Yingqi Wang, Mengmeng Zhang, Xueli Xu, Wenzhe Li, Wenshuang Gao, Xiao Sun, Qiang Zhu   +11 more
wiley   +1 more source

Mutagenesis and Repair of γ-Radiation- and Radical-Induced Tandem DNA Lesions

DNA
Ionizing radiation induces many different types of DNA lesions. But one of its characteristics is to produce complex DNA damage, of which tandem DNA damage has received much attention, owing to its promise of distinctive biological properties.
Ashis K. Basu, Laureen C. Colis, Jan Henric T. Bacurio   +2 more
doaj   +1 more source

Sustainable and Multifunctional Natural Macromolecular Polymers for Aqueous Zn Metal Batteries

Advanced Materials, EarlyView.
We comprehensively review the structure‐function relationships and regulatory mechanism of natural macromolecular polymers in stabilizing zinc anodes at the microscopic and mesoscopic scales. The interactions among polymer structures, optimization strategies, and regulatory mechanisms are discussed systematically summarizing recent related research ...
Yunuo Shi, Bo Jiang, Jingcheng Zhang, Xiaodong Shao, Peixun Xiong, Lutong Shan, Shengyang Huang, Mengfang Liang, Mengyao Chang, Fangyan Liu, Wenwu Li, Baoyu Xia, Wei Ji, Ho Seok Park   +13 more
wiley   +1 more source

Cartilage Delamination Flap Mimicking a Torn Medial Meniscus

Case Reports in Orthopedics, 2016
We report a case of a chondral delamination lesion due to medial parapatellar plica friction syndrome involving the medial femoral condyle. This mimicked a torn medial meniscus in clinical and radiological presentation.
Gan Zhi-Wei Jonathan, Hamid Rahmatullah Bin Abd Razak, Mitra Amit Kanta   +2 more
doaj   +1 more source

Non-nominal Experimental Bistatic SAR Acquisitions with TanDEM-X [PDF]

, 2012
TanDEM-X is a high-resolution interferometric mission with the main goal of providing a global and unprecedentedly accurate digital elevation model (DEM) of the Earth surface by means of single-pass X-band SAR interferometry.
Schulze, Daniel, Steinbrecher, Ulrich, Zink, Manfred, Moreira, Alberto, Prats, Pau, Reigber, Andreas, Younis, Marwan, Rodriguez-Cassola, Marc, Tous-Ramon, Nuria, Krieger, Gerhard, Lopez-Dekker, Paco   +10 more
core  

Flight Dynamics Operations of the TanDEM-X Formation [PDF]

, 2012
Since end of 2010 the German TerraSAR-X and TanDEM-X satellites are routinely operated as the first configurable single-pass Synthetic Aperture Radar interferometer in space. The two 1340 kg satellites fly in a 514 km sun-synchronous orbit.
Aida, Saika, Schlepp, Benjamin, Kirschner, Michael, Kahle, Ralph, Wermuth, Martin   +4 more
core   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Quality assessment of TanDEM-X Raw DEMs oriented to a fusion with CartoSAT-1 DEMs [PDF]

, 2013
This paper addresses a quality assessment of TanDEM-X standard Raw DEMs, with a resolution of 12 meters, for three different terrain configurations: urban areas, moderate topography and complex topography.
Reinartz, Peter, d'Angelo, Pablo, Eineder, Michael, Rossi, Cristian, Fritz, Thomas   +4 more
core  

Small molecule tandem organic photovoltaic cells incorporating an α-NPD optical spacer layer [PDF]

, 2013
We report an improvement in power conversion efficiency in a small molecule tandem organic photovoltaic (OPV) device by the optimisation of current balancing of the sub-cells using an optical spacer layer. A co-deposited layer of N,N’-bis(1-naphthyl)-N,N′
Howells, Thomas J., Jones, T. S. (Tim S.), Jones, Tim S., New, Edward G., Sullivan, Paul J., Howells, Thomas, New, Edward, Sullivan, Paul   +7 more
core   +1 more source