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Applications of Tandem Mass Spectrometry (MS/MS) in Protein Analysis for Biomedical Research

open access: yesMolecules, 2022
Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry (MALDI-MS).
Anca-Narcisa Neagu   +5 more
doaj   +3 more sources

Progressive search in tandem mass spectrometry

open access: yesBMC Bioinformatics, 2023
Background High-throughput Proteomics has been accelerated by (tandem) mass spectrometry. However, the slow speed of mass spectra analysis prevents the analysis results from being up-to-date.
Yoonsung Joh   +3 more
doaj   +3 more sources

Research Progress on Disulfide Bond Assignment Analysis Based on Mass Spectrometry [PDF]

open access: yesZhipu Xuebao, 2021
Disulfide bond in protein is an important post translational modification and it is extremely essential for stabilizing the three dimensional structure of proteins, maintaining the correct folded conformation and regulating their biological activities ...
LI Ming, WU Pei-ze
doaj   +1 more source

Simultaneous Method for Selected PBDEs and HBCDDs in Foodstuffs Using Gas Chromatography—Tandem Mass Spectrometry and Liquid Chromatography—Tandem Mass Spectrometry

open access: yesToxics, 2022
Flame retardants are added to consumer products to retard the ignition of combustible materials. Technical mixtures of polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCDD) were massively used for several decades.
Eva Lipičar   +3 more
doaj   +1 more source

Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies

open access: yesMetabolites, 2022
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn   +7 more
doaj   +1 more source

Lipid Peroxidation in Algae Oil: Antagonist Effects of Natural Antioxidants

open access: yesMolecules, 2022
Tandem mass spectrometry is proposed to check lipid oxidation, a free radical-mediated phenomenon which effects oxidative deterioration in polyunsaturated fatty acids. Antioxidants are used by the food industry to delay the oxidation process.
Ilaria Santoro   +4 more
doaj   +1 more source

Hybrid mass spectrometers for tandem mass spectrometry [PDF]

open access: yesJournal of the American Society for Mass Spectrometry, 2008
Mass spectrometers that use different types of analyzers for the first and second stages of mass analysis in tandem mass spectrometry (MS/MS) experiments are often referred to as "hybrid" mass spectrometers. The general goal in the design of a hybrid instrument is to combine different performance characteristics offered by various types of analyzers ...
Glish, Gary L., Burinsky, David J.
openaire   +2 more sources

Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories

open access: yesInternational Journal of Neonatal Screening, 2022
Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS).
Michael H. Gelb   +25 more
doaj   +1 more source

In Search of Disentanglement in Tandem Mass Spectrometry Datasets

open access: yesBiomolecules, 2023
Generative modeling and representation learning of tandem mass spectrometry data aim to learn an interpretable and instrument-agnostic digital representation of metabolites directly from MS/MS spectra.
Krzysztof Jan Abram, Douglas McCloskey
doaj   +1 more source

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