Results 1 to 10 of about 1,188,882 (284)
A Dynamic Programming Approach to De Novo Peptide Sequencing via Tandem Mass Spectrometry [PDF]
arXiv, 2001 The tandem mass spectrometry fragments a large number of molecules of the same peptide sequence into charged prefix and suffix subsequences, and then measures mass/charge ratios of these ions. The de novo peptide sequencing problem is to reconstruct the peptide sequence from a given tandem mass spectral data of k ions.
Chen, Ting +4 more
arxiv +8 more sources
Applications of Tandem Mass Spectrometry (MS/MS) in Protein Analysis for Biomedical Research
Molecules, 2022 Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry (MALDI-MS).
Anca-Narcisa Neagu +5 more
doaj +2 more sources
Analytical Chemistry, 2005 Native mass spectrometry is emerging as a powerful tool for the characterization of intact antibodies and antibody-based therapeutics. Here, we demonstrate new possibilities provided by the implementation of a high mass quadrupole mass selector on the ...
Belov, Mike +7 more
core +4 more sources
Quantification of hydroxyacetone and glycolaldehyde using chemical ionization mass spectrometry [PDF]
Atmospheric Chemistry and Physics, 2014 Chemical ionization mass spectrometry (CIMS) enables online, rapid, in situ detection and quantification of hydroxyacetone and glycolaldehyde. Two different CIMS approaches are demonstrated employing the strengths of single quadrupole mass spectrometry ...
J. M. St. Clair +5 more
doaj +4 more sources
Research Progress on Disulfide Bond Assignment Analysis Based on Mass Spectrometry [PDF]
Zhipu Xuebao, 2021 Disulfide bond in protein is an important post translational modification and it is extremely essential for stabilizing the three dimensional structure of proteins, maintaining the correct folded conformation and regulating their biological activities ...
LI Ming, WU Pei-ze
doaj +1 more source
Liquid chromatography–tandem mass spectrometry for clinical diagnostics
Nature Reviews Methods Primers, 2022 Mass spectrometry is a powerful analytical tool used for the analysis of a wide range of substances and matrices; it is increasingly utilized for clinical applications in laboratory medicine.
Stefani N. Thomas +4 more
semanticscholar +1 more source
Advanced tandem mass spectrometry in metabolomics and lipidomics—methods and applications
Analytical and Bioanalytical Chemistry, 2021 Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and selected analytes allow phenotypic characterization and serve as biomarkers, respectively.
S. Heiles
semanticscholar +1 more source
Progressive search in tandem mass spectrometry
BMC Bioinformatics, 2023 Background High-throughput Proteomics has been accelerated by (tandem) mass spectrometry. However, the slow speed of mass spectra analysis prevents the analysis results from being up-to-date.
Yoonsung Joh +3 more
doaj +1 more source
Toxics, 2022 Flame retardants are added to consumer products to retard the ignition of combustible materials. Technical mixtures of polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCDD) were massively used for several decades.
Eva Lipičar +3 more
doaj +1 more source
Metabolites, 2022 Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn +7 more
doaj +1 more source