Results 1 to 10 of about 972,565 (404)
Metabolites, 2022 Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn +7 more
doaj +1 more source
Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]
, 2005 In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Spöhrer, Ute, Vogeser, Michael
core +2 more sources
Lipid Peroxidation in Algae Oil: Antagonist Effects of Natural Antioxidants
Molecules, 2022 Tandem mass spectrometry is proposed to check lipid oxidation, a free radical-mediated phenomenon which effects oxidative deterioration in polyunsaturated fatty acids. Antioxidants are used by the food industry to delay the oxidation process.
Ilaria Santoro +4 more
doaj +1 more source
Antioxidants, 2020 In recent years, the consumption of polyphenols has been increasing, largely due to its beneficial effects on health. They are present in a wide variety of foods, but their extraction and characterization are complicated since they are mostly in complex ...
O. López-Fernández +5 more
semanticscholar +1 more source
Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories
International Journal of Neonatal Screening, 2022 Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS).
Michael H. Gelb +25 more
doaj +1 more source
In Search of Disentanglement in Tandem Mass Spectrometry Datasets
Biomolecules, 2023 Generative modeling and representation learning of tandem mass spectrometry data aim to learn an interpretable and instrument-agnostic digital representation of metabolites directly from MS/MS spectra.
Krzysztof Jan Abram, Douglas McCloskey
doaj +1 more source
Determination of Creatinine in Human Urine with Flow Injection Tandem Mass Spectrometry [PDF]
, 2012 Background/Aims: Excretion of urinary compounds in spot urine is often estimated relative to creatinine. For the growing number of liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays of urine-excreted molecules, a fast and accurate method ...
Koletzko, Berthold +2 more
core +1 more source
Measurement of kynurenine pathway metabolites by tandem mass spectrometry
Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023 Objectives: Recent studies have shown that derangements in kynurenine pathway metabolite levels are associated with various pathologies such as neurodegenerative diseases, schizophrenia, depression, bipolar disorder, rheumatoid arthritis, and cancer ...
Sedat Abusoglu +4 more
doaj +1 more source
Application of tandem two-dimensional mass spectrometry for top-down deep sequencing of calmodulin [PDF]
, 2018 Two-dimensional mass spectrometry (2DMS) involves simultaneous acquisition of the fragmentation patterns of all the analytes in a mixture by correlating their precursor and fragment ions by modulating precursor ions systematically through a fragmentation
Barrow, Mark P. +5 more
core +1 more source