Applications of Tandem Mass Spectrometry (MS/MS) in Protein Analysis for Biomedical Research
Molecules, 2022 Mass Spectrometry (MS) allows the analysis of proteins and peptides through a variety of methods, such as Electrospray Ionization-Mass Spectrometry (ESI-MS) or Matrix-Assisted Laser Desorption Ionization-Mass Spectrometry (MALDI-MS).
Anca-Narcisa Neagu +5 more
doaj +2 more sources
Progressive search in tandem mass spectrometry
BMC Bioinformatics, 2023 Background High-throughput Proteomics has been accelerated by (tandem) mass spectrometry. However, the slow speed of mass spectra analysis prevents the analysis results from being up-to-date.
Yoonsung Joh +3 more
doaj +3 more sources
Quantification of hydroxyacetone and glycolaldehyde using chemical ionization mass spectrometry [PDF]
Atmospheric Chemistry and Physics, 2014 Chemical ionization mass spectrometry (CIMS) enables online, rapid, in situ detection and quantification of hydroxyacetone and glycolaldehyde. Two different CIMS approaches are demonstrated employing the strengths of single quadrupole mass spectrometry ...
J. M. St. Clair +5 more
doaj +4 more sources
Tandem Native Mass-Spectrometry on Antibody-Drug Conjugates and Submillion Da Antibody-Antigen Protein Assemblies on an Orbitrap EMR Equipped with a High-Mass Quadrupole Mass Selector. [PDF]
Analytical Chemistry, 2015 Native mass spectrometry is emerging as a powerful tool for the characterization of intact antibodies and antibody-based therapeutics. Here, we demonstrate new possibilities provided by the implementation of a high mass quadrupole mass selector on the ...
A. Dyachenko +7 more
semanticscholar +5 more sources
Frontiers in Microbiology, 2019 Tandem mass spectrometry-based proteotyping allows characterizing microorganisms in terms of taxonomy and is becoming an important tool for investigating microbial diversity from several ecosystems.
Karim Hayoun +5 more
doaj +2 more sources
Two-dimensional mass spectrometry: new perspectives for tandem mass spectrometry [PDF]
European Biophysics Journal, 2019 Fourier transform ion cyclotron resonance mass analysers (FT-ICR MS) can offer the highest resolutions and mass accuracies in mass spectrometry. Mass spectra acquired in an FT-ICR MS can yield accurate elemental compositions of all compounds in a complex
M. V. van Agthoven +4 more
semanticscholar +6 more sources
Research Progress on Disulfide Bond Assignment Analysis Based on Mass Spectrometry [PDF]
Zhipu Xuebao, 2021 Disulfide bond in protein is an important post translational modification and it is extremely essential for stabilizing the three dimensional structure of proteins, maintaining the correct folded conformation and regulating their biological activities ...
LI Ming, WU Pei-ze
doaj +1 more source
Liquid chromatography–tandem mass spectrometry for clinical diagnostics
Nature Reviews Methods Primers, 2022 Mass spectrometry is a powerful analytical tool used for the analysis of a wide range of substances and matrices; it is increasingly utilized for clinical applications in laboratory medicine.
Stefani N. Thomas +4 more
semanticscholar +1 more source
Advanced tandem mass spectrometry in metabolomics and lipidomics—methods and applications
Analytical and Bioanalytical Chemistry, 2021 Metabolomics and lipidomics are new drivers of the omics era as molecular signatures and selected analytes allow phenotypic characterization and serve as biomarkers, respectively.
S. Heiles
semanticscholar +1 more source
Semi-automated serum steroid profiling with tandem mass spectrometry
Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023 Objectives: Highly selective and sensitive multi-analyte methods for the analysis of steroids are attractive for the diagnosis of endocrine diseases. Commercially available kits are increasingly used for this purpose.
Sophie Rakete +2 more
doaj +1 more source