Results 11 to 20 of about 235,828 (268)

In Search of Disentanglement in Tandem Mass Spectrometry Datasets

Biomolecules, 2023
Generative modeling and representation learning of tandem mass spectrometry data aim to learn an interpretable and instrument-agnostic digital representation of metabolites directly from MS/MS spectra.
Krzysztof Jan Abram, Douglas McCloskey
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Measurement of kynurenine pathway metabolites by tandem mass spectrometry

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023
Objectives: Recent studies have shown that derangements in kynurenine pathway metabolite levels are associated with various pathologies such as neurodegenerative diseases, schizophrenia, depression, bipolar disorder, rheumatoid arthritis, and cancer ...
Sedat Abusoglu, Duygu Eryavuz Onmaz, Gulsum Abusoglu, Fatma Humeyra Yerlikaya, Ali Unlu   +4 more
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Plasma free and total carnitine measured in children by tandem mass spectrometry

Brazilian Journal of Medical and Biological Research, 2002
Free and total carnitine quantification is important as a complementary test for the diagnosis of unusual metabolic diseases, including fatty acid degradation disorders.
J.H. Osorio, M. Pourfarzam
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Tandem mass spectrometry data quality assessment by self-convolution

BMC Bioinformatics, 2007
Background Many algorithms have been developed for deciphering the tandem mass spectrometry (MS) data sets. They can be essentially clustered into two classes.
Tham Wai, Choo Keng
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Water Circulation and Marine Environment in the Antarctic Traced by Speciation of 129I and 127I

Scientific Reports, 2017
Emissions of anthropogenic 129I from human nuclear activities are now detected in the surface water of the Antarctic seas. Surface seawater samples from the Drake Passage, Bellingshausen, Amundsen, and Ross Seas were analyzed for total 129I and 127I, as ...
Shan Xing, Xiaolin Hou, Ala Aldahan, Göran Possnert, Keliang Shi, Peng Yi, Weijian Zhou   +6 more
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BLINK enables ultrafast tandem mass spectrometry cosine similarity scoring

Scientific Reports, 2023
Metabolomics has a long history of using cosine similarity to match experimental tandem mass spectra to databases for compound identification. Here we introduce the Blur-and-Link (BLINK) approach for scoring cosine similarity.
Thomas V. Harwood, Daniel G. C. Treen, Mingxun Wang, Wibe de Jong, Trent R. Northen, Benjamin P. Bowen   +5 more
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Sucrose gradient chromatin enrichment for quantitative proteomics analysis in budding yeast

STAR Protocols, 2021
Summary: Here, we describe a fractionation protocol optimized to quantify changes in relative abundance of the chromatin-bound proteome (chromatome) by tandem mass tag multiplexing-based tandem mass spectrometry. It has been applied to yeast cells before
Kiran Challa, Jan Seebacher, Susan M. Gasser   +2 more
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Seminolipid and its precursor/degradative product, galactosylalkylacylglycerol, in the testis of saposin A- and prosaposin-deficient mice

Journal of Lipid Research, 2003
Sphingolipid activator proteins (saposins A, B, C, and D) are derived from a common precursor protein (prosaposin) and specifically activate in vivo degradation of glycolipids with short carbohydrate chains.
Keiko Tadano-Aritomi, Junko Matsuda, Hirokazu Fujimoto, Kunihiko Suzuki, Ineo Ishizuka   +4 more
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Gas-Phase Fragmentation of Cyclic Oligosaccharides in Tandem Mass Spectrometry

Molecules, 2019
Modern mass spectrometry, including electrospray and MALDI, is applied for analysis and structure elucidation of carbohydrates. Cyclic oligosaccharides isolated from different sources (bacteria and plants) have been known for decades and some of them ...
Alexander O. Chizhov, Yury E. Tsvetkov, Nikolay E. Nifantiev   +2 more
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