Lipid Peroxidation in Algae Oil: Antagonist Effects of Natural Antioxidants
Molecules, 2022 Tandem mass spectrometry is proposed to check lipid oxidation, a free radical-mediated phenomenon which effects oxidative deterioration in polyunsaturated fatty acids. Antioxidants are used by the food industry to delay the oxidation process.
Ilaria Santoro +4 more
doaj +1 more source
Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]
, 2005 In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Spöhrer, Ute, Vogeser, Michael
core +2 more sources
Sampling the proteome by emerging single-molecule and mass-spectrometry methods [PDF]
Nat Methods 20, 339--346 (2023), 2022 Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine these implications for both liquid chromatography-tandem mass spectrometry (LC-MS/MS) and single-molecule counting ...
arxiv +1 more source
Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories
International Journal of Neonatal Screening, 2022 Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS).
Michael H. Gelb +25 more
doaj +1 more source
In Search of Disentanglement in Tandem Mass Spectrometry Datasets
Biomolecules, 2023 Generative modeling and representation learning of tandem mass spectrometry data aim to learn an interpretable and instrument-agnostic digital representation of metabolites directly from MS/MS spectra.
Krzysztof Jan Abram, Douglas McCloskey
doaj +1 more source
Interferometric mass spectrometry [PDF]
, 2021 Accelerator mass spectrometry (AMS) is a widely-used technique with multiple applications, including geology, molecular biology and archeology. In order to achieve a high dynamic range, AMS requires tandem accelerators and large magnets, which thus confines it to big laboratories.
arxiv +1 more source
Determination of Creatinine in Human Urine with Flow Injection Tandem Mass Spectrometry [PDF]
, 2012 Background/Aims: Excretion of urinary compounds in spot urine is often estimated relative to creatinine. For the growing number of liquid chromatography-tandem mass spectrometry (LC-MS/MS) assays of urine-excreted molecules, a fast and accurate method ...
Koletzko, Berthold +2 more
core +1 more source
Application of tandem two-dimensional mass spectrometry for top-down deep sequencing of calmodulin [PDF]
, 2018 Two-dimensional mass spectrometry (2DMS) involves simultaneous acquisition of the fragmentation patterns of all the analytes in a mixture by correlating their precursor and fragment ions by modulating precursor ions systematically through a fragmentation
Barrow, Mark P. +5 more
core +1 more source
Plasma free and total carnitine measured in children by tandem mass spectrometry
Brazilian Journal of Medical and Biological Research, 2002 Free and total carnitine quantification is important as a complementary test for the diagnosis of unusual metabolic diseases, including fatty acid degradation disorders.
J.H. Osorio, M. Pourfarzam
doaj +1 more source