Results 11 to 20 of about 968,042 (404)

Ocrelizumab quantitation by liquid chromatography-tandem mass spectrometry

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2022
Introduction: Ocrelizumab is a monoclonal anti-CD20 antibody approved for the treatment of multiple sclerosis (MS). The clinical value of therapeutic drug monitoring (TDM) for this antibody in treatment of MS is unknown, and an adequately specific and ...
Erik I. Hallin, Trond Trætteberg Serkland, Kjell-Morten Myhr, Øivind Torkildsen, Silje Skrede   +4 more
doaj   +1 more source

Simultaneous Method for Selected PBDEs and HBCDDs in Foodstuffs Using Gas Chromatography—Tandem Mass Spectrometry and Liquid Chromatography—Tandem Mass Spectrometry

Toxics, 2022
Flame retardants are added to consumer products to retard the ignition of combustible materials. Technical mixtures of polybrominated diphenyl ethers (PBDEs) and hexabromocyclododecane (HBCDD) were massively used for several decades.
Eva Lipičar, Danijela Fras, Nino Javernik, Helena Prosen   +3 more
doaj   +1 more source

Correlating Mass Spectrometry Imaging and Liquid Chromatography-Tandem Mass Spectrometry for Tissue-Based Pharmacokinetic Studies

Metabolites, 2022
Liquid chromatography-tandem mass spectrometry (LC-MS/MS) is a standard tool used for absolute quantification of drugs in pharmacokinetic (PK) studies.
Andreas Dannhorn, Emine Kazanc, Gregory Hamm, John G. Swales, Nicole Strittmatter, Gareth Maglennon, Richard J. A. Goodwin, Zoltan Takats   +7 more
doaj   +1 more source

Pitfall in the high-throughput quantification of whole blood cyclosporin A using liquid chromatography-tandem mass spectrometry [PDF]

, 2005
In a growing number of laboratories the technique of liquid chromatography-tandem mass spectrometry is used for the quantification of cyclosporin A in whole blood, employing cyclosporin D as the internal standard. Cyclosporin A is extensively metabolized
Spöhrer, Ute, Vogeser, Michael
core   +2 more sources

Lipid Peroxidation in Algae Oil: Antagonist Effects of Natural Antioxidants

Molecules, 2022
Tandem mass spectrometry is proposed to check lipid oxidation, a free radical-mediated phenomenon which effects oxidative deterioration in polyunsaturated fatty acids. Antioxidants are used by the food industry to delay the oxidation process.
Ilaria Santoro, Anna Russo, Enzo Perri, Giovanni Sindona, Monica Nardi   +4 more
doaj   +1 more source

Determination of Polyphenols Using Liquid Chromatography–Tandem Mass Spectrometry Technique (LC–MS/MS): A Review

Antioxidants, 2020
In recent years, the consumption of polyphenols has been increasing, largely due to its beneficial effects on health. They are present in a wide variety of foods, but their extraction and characterization are complicated since they are mostly in complex ...
O. López-Fernández, R. Domínguez, M. Pateiro, P. E. Munekata, G. Rocchetti, J. Lorenzo   +5 more
semanticscholar   +1 more source

Liquid Chromatography–Tandem Mass Spectrometry in Newborn Screening Laboratories

International Journal of Neonatal Screening, 2022
Tandem mass spectrometry (MS/MS) is the most universal platform currently available for the analysis of enzymatic activities and biomarkers in dried blood spots (DBS) for applications in newborn screening (NBS).
Michael H. Gelb, Khaja Basheeruddin, Alberto Burlina, Hsiao-Jan Chen, Yin-Hsiu Chien, George Dizikes, Christine Dorley, Roberto Giugliani, Amy Hietala, Xinying Hong, Shu-Min Kao, Hamid Khaledi, Tracy Klug, Francyne Kubaski, Hsuan-Chieh Liao, Monica Martin, Adrienne Manning, Joseph Orsini, Yin Peng, Enzo Ranieri, Andreas Rohrwasser, Nicolas Szabo-Fresnais, Coleman T. Turgeon, Frédérick M. Vaz, Li-yun Wang, Dietrich Matern   +25 more
doaj   +1 more source

Liquid chromatography–tandem mass spectrometry [PDF]

Analytical and Bioanalytical Chemistry, 2013
Peer ...
M. Petrovíc, D. Barceló
semanticscholar   +5 more sources

In Search of Disentanglement in Tandem Mass Spectrometry Datasets

Biomolecules, 2023
Generative modeling and representation learning of tandem mass spectrometry data aim to learn an interpretable and instrument-agnostic digital representation of metabolites directly from MS/MS spectra.
Krzysztof Jan Abram, Douglas McCloskey
doaj   +1 more source

Measurement of kynurenine pathway metabolites by tandem mass spectrometry

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023
Objectives: Recent studies have shown that derangements in kynurenine pathway metabolite levels are associated with various pathologies such as neurodegenerative diseases, schizophrenia, depression, bipolar disorder, rheumatoid arthritis, and cancer ...
Sedat Abusoglu, Duygu Eryavuz Onmaz, Gulsum Abusoglu, Fatma Humeyra Yerlikaya, Ali Unlu   +4 more
doaj   +1 more source