Results 221 to 230 of about 988,611 (339)

MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis

Advanced Science, EarlyView.
MeCP2 lactylation protects against ischemic stroke by reducing brain infarct volume and improving neurological outcomes. Lactylation at K210/K249 exerts neuroprotective effects by repressing the transcription of apoptosis‐associated genes, including Pdcd4 and Pla2g6. HDAC3 and p300 serve as key regulatory enzymes for MeCP2 lactylation following stroke.
Min Sun, Yuxin Zhang, Rui Mao, Yan Chen, Pinyi Liu, Lei Ye, Siyi Xu, Junqiu Jia, Shu Shu, Huiya Li, Yanping Yin, Shengnan Xia, Yanting Chen, Yun Xu   +13 more
wiley   +1 more source

Dereplication of Natural Product Antifungals via Liquid Chromatography-Tandem Mass Spectrometry and Chemical Genomics. [PDF]

Molecules
Brittin NJ, Aceti DJ, Braun DR, Anderson JM, Ericksen SS, Rajski SR, Currie CR, Andes DR, Bugni TS.   +8 more
europepmc   +1 more source

Measurement of trimethylamine-N-oxide by stable isotope dilution liquid chromatography tandem mass spectrometry.

Analytical Biochemistry, 2014
Zeneng Wang, B. Levison, Jennie E. Hazen, Lillian M. Donahue, Xin-Min Li, S. Hazen   +5 more
semanticscholar   +1 more source

Quantification of 8-oxo-guanine and guanine as the nucleobase, nucleoside and deoxynucleoside forms in human urine by high-performance liquid chromatography-electrospray tandem mass spectrometry [PDF]

, 2002
Allan Weimann
openalex   +1 more source

Diallyl Trisulfide From Garlic Regulates RAB18 Phase Separation to Inhibit Lipophagy and Induce Cuproptosis in Hepatic Stellate Cells for Antifibrotic Effects

Advanced Science, EarlyView.
Diallyl trisulfides (DATs) selectively induce cuproptosis in hepatic stellate cells (HSCs) by targeting Ras‐related protein Rab‐18 (RAB18) and regulating lipophagy. DATs promote RAB18 phase separation, enhance mitochondrial‐associated membrane structures (MAMs) formation, and increase succinylation of dihydrolipoamide dehydrogenase (DLD) at K320.
Haoyuan Tian, Shujiang Sun, Xinran Qiu, Junrui Wang, Yuanyuan Gao, Jianmei Chen, Xiang Han, Zhengyang Bao, Xiaohan Guo, Yuqi Sun, Yuxin Lin, Mengru Hu, Feng Zhang, Zili Zhang, Feixia Wang, Shizhong Zheng, Jiangjuan Shao   +16 more
wiley   +1 more source

Residue of allocryptopine and protopine in tissues and eggs of laying hens using ultra-high performance liquid chromatography-tandem mass spectrometry. [PDF]

Poult Sci
Liu M, Xu J, Jing Y, Yao K, Tang Z, Zeng J, Yang Z.   +6 more
europepmc   +1 more source

METLIN: A Tandem Mass Spectral Library of Standards.

Methods in molecular biology, 2020
J. R. Montenegro-Burke, Carlos Guijas, G. Siuzdak   +2 more
semanticscholar   +1 more source

Determination of Capsaicin, Nonivamide, and Dihydrocapsaicin in Blood and Tissue by Liquid Chromatography-Tandem Mass Spectrometry [PDF]

, 2002
Christopher A. Reilly, Dennis J. Crouch, Garold S. Yost, Alim A. Fatah   +3 more
openalex   +1 more source

RAB3B Dictates mTORC1/S6 Signaling in Chordoma and Predicts Response to mTORC1‐Targeted Therapy

Advanced Science, EarlyView.
RAB3B is unveiled as a prominent oncogenic regulator in chordoma, which can block the DUSP12‐mediated dephosphorylation of p‐S6 (S235/236). The combination of RAB3B and p‐S6 indicates a good prognostic value and predicts mTORC1 inhibitors response for chordoma patients.
Jianxuan Gao, Jiali Jin, Runzhi Huang, Siqiao Wang, Sihui Song, Yu Zhang, Yongai Li, Jun Lin, Zhengyan Chang, Zongqiang Huang, Wei Sun, Huabin Yin, Dianwen Song, Jianru Xiao, Ping Wang, Tong Meng   +15 more
wiley   +1 more source

Determination of Flavonoid Glycoside Isomers Using Vision Transformer and Tandem Mass Spectrometry. [PDF]

Plants (Basel)
Park JI, Kim MJ, Lee KH, Oh SH, Kang YH, Kim H.   +5 more
europepmc   +1 more source