Results 251 to 260 of about 418,182 (306)

Tandem Mass Spectrometry

Science, 1981
Coupling mass spectrometers in series provides a new technique that has many advantages for the analysis of specific organic compounds in complex mixtures. Sensitivity to picograms of targeted compounds can be achieved with high specificity and nearly instantaneous response.
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Tandem Mass Spectrometry in Physiology

Physiology, 2007
Tandem mass spectrometry coupled to liquid chromatography (LC-MS/MS) allows identification of proteins in a complex mixture without need for protein purification (“shotgun” proteomics). Recent progress in LC-MS/MS-based quantification, phosphoproteomic analysis, and targeted LC-MS/MS using multiple reaction monitoring (MRM) has made LC-MS/MS a powerful
Trairak, Pisitkun   +3 more
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Tandem mass spectrometry — The potential

Journal of Inherited Metabolic Disease, 1999
AbstractWe summarize the current status of the use of tandem mass spectrometry for the detection of inherited metabolic disorders and the investigation of the pathophysiology of these conditions. We also indicate some of the more recent developments of this technology that have potential diagnostic applications.
K, Bartlett, M, Pourfarzam
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Mass Spectrometry and Tandem Mass Spectrometry of Citrus Limonoids

Analytical Chemistry, 2003
Methods for atmospheric pressure chemical ionization tandem mass spectrometry (APCI-MS/MS) of citrus limonoid aglycones and electrospray ionization tandem mass spectrometry (ESI-MS/MS) of limonoid glucosides are reported. The fragmentation patterns of four citrus limonoid aglycones (limonin, nomilin, obacunone, and deacetylnomilin) and six limonoid ...
Qingguo, Tian, Steven J, Schwartz
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Tandem mass spectrometry

2019
This chapter highlights the basic principles of ion fragmentation in a mass spectrometer and examines the methods used to induce dissociation. It describes the common tandem mass spectrometer designs and explains the experiments they make possible. It also mentions electron ionization (EI) as one of the methods of ionization that impart sufficient ...
James McCullagh, Neil Oldham
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Tandem Mass Spectrometry

2003
For more than 30 years, electron ionization mass spectrometry (EIMS) has played a key role in the structural determination of small biological compounds, largely because it has three advantages to offer: very high sensitivity compared to other structural methods, such as nuclear magnetic resonance and infrared spectrometry, the possibility for analysis
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