Results 21 to 30 of about 418,182 (306)
Sucrose gradient chromatin enrichment for quantitative proteomics analysis in budding yeast
Summary: Here, we describe a fractionation protocol optimized to quantify changes in relative abundance of the chromatin-bound proteome (chromatome) by tandem mass tag multiplexing-based tandem mass spectrometry. It has been applied to yeast cells before
Kiran Challa +2 more
doaj +1 more source
Economics of tandem mass spectrometry screening of neonatal inherited disorders [PDF]
Objectives: The aim of this study was to evaluate the cost-effectiveness of neonatal screening for phenylketonuria (PKU) and medium-chain acyl-coA dehydrogenase (MCAD) deficiency using tandem mass spectrometry (tandem MS). Methods: A systematic review
Beverley, C. +4 more
core +1 more source
Improved mass accuracy for tandem mass spectrometry [PDF]
With the emergence of top-down proteomics, the ability to achieve high mass measurement accuracy on tandem MS/MS data will be beneficial for protein identification and characterization. (FT-ICR) Fourier transform ion cyclotron resonance mass spectrometers are the ideal instruments to perform these experiments with their ability to provide high ...
Kaiser, Nathan K. +2 more
openaire +2 more sources
Sphingolipid activator proteins (saposins A, B, C, and D) are derived from a common precursor protein (prosaposin) and specifically activate in vivo degradation of glycolipids with short carbohydrate chains.
Keiko Tadano-Aritomi +4 more
doaj +1 more source
The gas phase cyclization of deprotonated N-aryl-2-cyano-2-diazoacetamides [PDF]
The document attached has been archived with permission from the publisher.1-Aryl-4-cyano-5-hydroxy-1,2,3-triazoles can be obtained in solution by base-catalysed cyclization of N-aryl-2-cyano-2-diazoacetamides.
Bilusich, D. +6 more
core +2 more sources
An updated map of Trypanosoma cruzi histone post-translational modifications
Measurement(s) histone_modification Technology Type(s) mass spectrometry • nanoflow liquid chromatography-tandem mass spectrometry • Data-Dependent Acquisition Sample Characteristic - Organism Trypanosoma cruzi Machine-accessible metadata file describing
Rafael Fogaça de Almeida +2 more
doaj +1 more source
Quantification of voriconazole in plasma by liquid chromatography-tandem mass spectrometry [PDF]
A convenient liquid chromatography-tandem mass spectrometry method for the quantification of the triazole antifungal agent voriconazole in plasma samples is described. Fenbuconazole is used as an internal standard.
Boyd +16 more
core +1 more source
From sequence-defined macromolecules to macromolecular pin codes [PDF]
Dynamic sequence-defined oligomers carrying a chemically written pin code are obtained through a strategy combining multicomponent reactions with the thermoreversible addition of 1,2,4-triazoline-3,5-diones (TADs) to indole substrates.
Badi, Nezha +4 more
core +1 more source
Gas-Phase Fragmentation of Cyclic Oligosaccharides in Tandem Mass Spectrometry
Modern mass spectrometry, including electrospray and MALDI, is applied for analysis and structure elucidation of carbohydrates. Cyclic oligosaccharides isolated from different sources (bacteria and plants) have been known for decades and some of them ...
Alexander O. Chizhov +2 more
doaj +1 more source
Native mass spectrometry is emerging as a powerful tool for the characterization of intact antibodies and antibody-based therapeutics. Here, we demonstrate new possibilities provided by the implementation of a high mass quadrupole mass selector on the ...
Belov, Mike +7 more
core +3 more sources

