Results 21 to 30 of about 286,551 (289)

Ocrelizumab quantitation by liquid chromatography-tandem mass spectrometry

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2022
Introduction: Ocrelizumab is a monoclonal anti-CD20 antibody approved for the treatment of multiple sclerosis (MS). The clinical value of therapeutic drug monitoring (TDM) for this antibody in treatment of MS is unknown, and an adequately specific and ...
Erik I. Hallin, Trond Trætteberg Serkland, Kjell-Morten Myhr, Øivind Torkildsen, Silje Skrede   +4 more
doaj  

BLINK enables ultrafast tandem mass spectrometry cosine similarity scoring

Scientific Reports, 2023
Metabolomics has a long history of using cosine similarity to match experimental tandem mass spectra to databases for compound identification. Here we introduce the Blur-and-Link (BLINK) approach for scoring cosine similarity.
Thomas V. Harwood, Daniel G. C. Treen, Mingxun Wang, Wibe de Jong, Trent R. Northen, Benjamin P. Bowen   +5 more
doaj   +1 more source

Tandem Mass Spectrometry of Peptides [PDF]

, 2012
Renata Soares1, Elisabete Pires1, Andre M. Almeida1,2, Romana Santos1,3, Ricardo Gomes1, Kamila Koci1, Catarina Ferraz Franco1 and Ana Varela Coelho1 1ITQB/Universidade Nova de Lisboa 2Instituto de Investigacao Cientifica Tropical& Centro Interdisciplinar de Investigacao em Sanidade Animal 3Unidade de Investigacao em Ciencias Orais e Biomedicas ...
Renata Soares, Kamila Koci, Romana Santos, Elisabete Pires, Ana Varela Coelho, Ricardo Gomes, Catarina Franco, André M. Almeida   +7 more
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Semi-automated serum steroid profiling with tandem mass spectrometry

Journal of Mass Spectrometry and Advances in the Clinical Lab, 2023
Objectives: Highly selective and sensitive multi-analyte methods for the analysis of steroids are attractive for the diagnosis of endocrine diseases. Commercially available kits are increasingly used for this purpose.
Sophie Rakete, Tom Schubert, Michael Vogeser   +2 more
doaj  

Gas-Phase Fragmentation of Cyclic Oligosaccharides in Tandem Mass Spectrometry

Molecules, 2019
Modern mass spectrometry, including electrospray and MALDI, is applied for analysis and structure elucidation of carbohydrates. Cyclic oligosaccharides isolated from different sources (bacteria and plants) have been known for decades and some of them ...
Alexander O. Chizhov, Yury E. Tsvetkov, Nikolay E. Nifantiev   +2 more
doaj   +1 more source

Mass Spectrometry and Tandem Mass Spectrometry: An Overview [PDF]

, 2014
In this chapter, a brief overview of fundamentals in mass spectrometry and of its applications in homeland security, forensic sciences and explosive detection, are presented.
openaire   +3 more sources

Method development and validation of HPLC tandem/mass spectrometry for quantification of perindopril arginine and amlodipine besylate combination in bulk and pharmaceutical formulations

Research in Pharmaceutical Sciences, 2017
A well-characterized and fully validated ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometric (UHPLC-ESI-MS/MS) method was developed to reliably analyze combination of perindopril arginine and amlodipine besylate
Kalaiyarasi Duraisamy, K S Jaganathan, Marothu Vamsi krishna   +2 more
doaj   +1 more source

An updated map of Trypanosoma cruzi histone post-translational modifications

Scientific Data, 2021
Measurement(s) histone_modification Technology Type(s) mass spectrometry • nanoflow liquid chromatography-tandem mass spectrometry • Data-Dependent Acquisition Sample Characteristic - Organism Trypanosoma cruzi Machine-accessible metadata file describing
Rafael Fogaça de Almeida, Matheus Fernandes, Lyris Martins Franco de Godoy   +2 more
doaj   +1 more source

Electrospray mass spectrometry and tandem mass spectrometry of bimetallic oxovanadium complexes [PDF]

Journal of the American Society for Mass Spectrometry, 2008
A series of six bimetallic oxovanadium complexes (1-6; only one was purified) were investigated by electrospray quadrupole time-of-flight tandem mass spectrometry (ESI-QTOF-MS/MS) in negative-ion mode. Radical molecular anions [M]*(-) were observed in MS mode.
Guolin Zhang, Xiao-Ying Xu, Shi-Wei Luo, Zhi-Jun Wu, Dong-Mei Fang   +4 more
openaire   +3 more sources

Efficacy and outcome of expanded newborn screening for metabolic diseases - Report of 10 years from South-West Germany *

Orphanet Journal of Rare Diseases, 2011
Background National newborn screening programmes based on tandem-mass spectrometry (MS/MS) and other newborn screening (NBS) technologies show a substantial variation in number and types of disorders included in the screening panel.
Mengel Eugen, Trefz Friedrich K, Tacke Uta, Schwab Karl O, Fang-Hoffmann Junmin, Haege Gisela, Gramer Gwendolyn, Lindner Martin, Wendel Udo, Leichsenring Michael, Burgard Peter, Hoffmann Georg F   +11 more
doaj   +1 more source