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Asymmetric Tandem Reactions: New Strategies and Applications
Phosphorus, Sulfur, and Silicon and the Related Elements, 2013Abstract The application of allylic sulphoxides and, particularly, the chiral amine reagent tert-butanesulphinamide has been extended to three different tandem processes. The condensation of (R)-(+)-allyl p-tolyl sulphoxide, fluorinated nitriles and alkyl propiolates led to a new family of enantiomerically pure fluorine-containing 1,4- dihydropyridines.
Santos Fustero +2 more
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A New Strategy of Discrimination of a Point Mutation by Tandem of Short Oligonucleotides
Nucleosides, Nucleotides and Nucleic Acids, 2000A new strategy based on the use of cooperative tandems of short oligonucleotide derivatives (TSOD) has been proposed to discriminate a "right" DNA target from a target containing a single nucleotide discrepancy. Modification of a DNA target by oligodeoxyribonucleotide reagents was used to characterize their interaction in the perfect and mismatched ...
D V, Pyshnyi +4 more
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Tandem Repeat Peptide Strategy for the Design of Neurotrophic Factor Mimetics
CNS & Neurological Disorders - Drug Targets, 2008Neurotrophic factors comprise a broad family of secreted proteins that have growth promoting, survival promoting and differentiation inducing activities. Disruption of neurotrophic factor signalling is a characteristic of many central and peripheral nervous system disorders, such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral ...
Gareth Williams +5 more
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Automated protein identification by tandem mass spectrometry: Issues and strategies
Mass Spectrometry Reviews, 2005AbstractProtein identification by tandem mass spectrometry (MS/MS) is key to most proteomics projects and has been widely explored in bioinformatics research. Obtaining good and trustful identification results has important implications for biological and clinical work.
Hernandez P, Müller M, Appel RD
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Expression of Short Peptide by an Improved Isocaudamer Tandem Repeat Strategy
Protein & Peptide Letters, 2013An improved isocaudamer tandem repeat strategy for the production of short functional peptide was demonstrated in the study. The coding sequence of short peptide was codon optimized, and two isocaudamers were induced into the end of coding sequence. By re-cutting with isocaudamers and re-ligating, the coding sequence of short peptide in the expression ...
Tong-Qing, An +6 more
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The Network Game: Analyzing Network-Formation and Interaction Strategies in Tandem
2008 IEEE/WIC/ACM International Conference on Web Intelligence and Intelligent Agent Technology, 2008In networks, autonomous nodes have action choices along two dimensions: They can forward/process incoming service requests - or not, and they can establish new links and maintain or terminate existing ones. In other words, a node can choose both an action-selection and a link-selection strategy.
Björn-Oliver Hartmann +2 more
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A Pulsed Tandem Electrocatalysis Strategy for CO2 Reduction
Journal of the American Chemical SocietyElectroreduction of CO2 to value-added C2 products remains hindered by sluggish C-C coupling kinetics and competing side reactions. Inspired by the tandem catalytic mechanisms of multienzyme systems, we designed a dual-site single-atom nanozyme (DSAN) comprising FeN4 and FeO4 sites (FeN4-FeO4).
Hao, Sun, Jing-Yao, Liu
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A strategy of the longitudinal control for the tandem wing configuration design
Aircraft Engineering and Aerospace Technology, 2022Purpose This paper presents first sight on the longitudinal control strategy for an aircraft in the tandem wing configuration. It is an aerodynamic strongly coupled configuration that needs a lot of detailed aerodynamic analysis which describes the mutual impact of the main parts of the aircraft.
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Tandem Prins Strategy for the Synthesis of Spiropyrrolidine and Spiropiperidine Derivatives
European Journal of Organic Chemistry, 2015AbstractCascade cyclization of a 3‐[(3‐methylbut‐2‐enylamino)methyl]but‐3‐en‐1‐ol derivative with aldehydes in the presence of TMSOTf at 0 °C under mild conditions provides the corresponding spiropyrrolidine scaffolds in good yields. Similar cyclization of a 3‐[(4‐methylpent‐3‐enylamino)methyl]but‐3‐en‐1‐ol derivative with aldehydes affords the ...
Basi V. Subba Reddy +6 more
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[Molecular tandem repeat strategy for production ofultrashort peptides].
Sheng wu gong cheng xue bao = Chinese journal of biotechnology, 2023Ultrashort peptides have higher stability, tissue penetrability, biocompatibility, and less immunogenicity, and are widely applied in biology and medicine. GHK (glycyl-l-histidyl-l-lysine) and GQPR (glycyl-l-glutamyl-l-prolyl-l-arginine) can stimulate collagen renewal and inhibit collagen degradation.
Chen, Zhao +3 more
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