Results 71 to 80 of about 5,178 (152)

Rosmarinic Acid Synthase 1 Phosphorylation by SmMAPK3 Is Required for Salicylic Acid‐Induced Salvianolic Acid Accumulation in Salvia miltiorrhiza Hairy Roots

Plant Biotechnology Journal, Volume 24, Issue 2, Page 734-751, February 2026.
ABSTRACT Salvianolic acid is the main active component of Salvia miltiorrhiza and holds significant value in the clinical treatment of myocardial ischemia and hypoxia. Previous studies have shown that salicylic acid (SA) can significantly promote the accumulation of salvianolic acid, but its molecular mechanism remains incompletely understood.
Xuecui Yin, Shuang Liu, Yuhang Zhang, Wenjing Yang, Junwen Bu, Bin Zhang, Juane Dong   +6 more
wiley   +1 more source

Astragalus membranaceus—Salvia miltiorrhiza Decoction Ameliorates Metabolic Syndrome and Gut Microbiota Dysbiosis Induced by High‐Fat Diet: A Comparative Study

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
The optimal pairing ratio of ASDs against hyperlipidemia was systematically investigated. ASD maintains intestinal homeostasis and improves the systemic inflammatory response. A new LC–MS/MS method for the determination of derivatized SCFAs was established. ASD regulates the gut microbiota and its metabolites (SCFAs and BAs).
Haiyin Zhang, Haofang Wan, Yihang Lu, Yu He, Haitong Wan, Chang Li   +5 more
wiley   +1 more source

Paeoniflorin Ameliorates Spinal Cord Injury by Controlling Apoptosis and Ferroptosis in H2O2‐Damaged PC12 Cells

Immunity, Inflammation and Disease, Volume 14, Issue 1, January 2026.
ABSTRACT Background Spinal cord injury (SCI) leads to severe neurological dysfunction. Current therapeutic strategies remain limited, with poor recovery rates. Oxidative stress and ferroptosis are key mechanisms underlying secondary SCI. Paeoniflorin has anti‐inflammatory, antioxidant, and neuroprotective properties; however, its role in regulating ...
Zongyu Zhang, Zhijing Zhou, Peng Zhang, Yongfeng Huo   +3 more
wiley   +1 more source

Tanshinone IIA Alleviates Traumatic Brain Injury by Reducing Ischemia‒Reperfusion via the miR-124-5p/FoxO1 Axis

Mediators of Inflammation
Background. Cerebral ischemia–reperfusion injury is a common complication of ischemic stroke that affects the prognosis of patients with ischemic stroke.
Wenbing Su, Meifen Lv, Dayu Wang, Yinghong He, Hui Han, Yu Zhang, Xiuying Zhang, Shaokun Lv, Liqing Yao   +8 more
doaj   +1 more source

Exosome‐Based Cartilage‐Targeted Delivery System: Strategies and Applications

Small Science, Volume 6, Issue 1, January 2026.
Construction strategies and applications of cartilage‐targeting exosomes. With the ageing of the global population, cartilage‐related diseases, such as osteoarthritis (OA) and intervertebral disc degeneration (IVDD), have increasingly become significant social problems threatening human health. Therefore, targeted therapy for cartilage is becoming more
Yao Wang, Bo Chen, Haodong Zhu, Zhenyu Sun   +3 more
wiley   +1 more source

Growth Inhibition of Tanshinones on SPC-A-1 Cell Line and their Structure-activity Relationship

Chinese Journal of Lung Cancer, 2011
Background and objective Numerous studies have shown that Tanshinones have anti-tumor effects in vitro, but few studies were focusing on the anti-tumor activity of Tanshinones against one special cancer cell line.
Huayue SHI, Qing ZHANG, Hui LI, Ting CHU, Hui JIN, Shengjun MAO   +5 more
doaj  

Identification of tanshinone I as cap-dependent endonuclease inhibitor with broad-spectrum antiviral effect. [PDF]

J Virol, 2023
He X, Yang F, Wu Y, Lu J, Gao X, Zhu X, Yang J, Liu S, Xiao G, Pan X.   +9 more
europepmc   +1 more source

The enhanced cytotoxicity on breast cancer cells by Tanshinone I-induced photodynamic effect. [PDF]

Sci Rep, 2023
Fengchao C, Siya Z, Tongtong Y, Hongquan W, Jie L, Qiang W, Danish S, Kun L.   +7 more
europepmc   +1 more source

Molecular docking and molecular dynamics simulation revealed potential compounds in Salvia miltiorrhiza for inhibiting enzymes and receptors in Alzheimer’s disease

Vietnam Journal of Science, Technology and Engineering
Alzheimer’s disease is an age-related neurodegenerative disorder that leads to cognitive and functional decline. Potential target proteins for managing Alzheimer’s disease include Acetylcholinesterase (AChE), Butyrylcholinesterase (BuChE), Beta ...
Tung Bui Thanh, Trang Vu Dai, Huong Le Thi   +2 more
doaj   +3 more sources

UHPLC-QTOF-MS-Based Targeted Metabolomics Provides Novel Insights into the Accumulative Mechanism of Soil Types on the Bioactive Components of Salvia miltiorrhiza

Molecules
The root of Salvia miltiorrhiza Bunge (SMB) has been widely used to treat cardiovascular diseases. However, the contents of secondary metabolites in the roots from different production areas are significantly different, and the impact of soil factors on ...
Mengmeng Hou, Dan Gao, Weixu Chen, Wenjun Jiang, Dade Yu, Xiwen Li   +5 more
doaj   +1 more source