Results 61 to 70 of about 7,870 (219)

Simultaneous Determination of Four Tanshinones by UPLC-TQ/MS and Their Pharmacokinetic Application after Administration of Single Ethanol Extract of Danshen Combined with Water Extract in Normal and Adenine-Induced Chronic Renal Failure Rats

Molecules, 2016
Salvia miltiorrhiza, one of the major traditional Chinese medicines, is commonly used and the main active ingredients—tanshinones—possess the ability to improve renal function.
Hong-Die Cai, Shu-Lan Su, Yonghui Li, Zhenhua Zhu, Jianming Guo, Yue Zhu, Sheng Guo, Dawei Qian, Jinao Duan   +8 more
doaj   +1 more source

Tanshinone IIA inhibits cardiomyocyte pyroptosis through TLR4/NF-κB p65 pathway after acute myocardial infarction

Frontiers in Cell and Developmental Biology, 2023
Background: Tanshinone IIA, derived from Radix Salviae Miltiorrhizae (Salvia miltiorrhiza Bunge), constitutes a significant component of this traditional Chinese medicine.
Ruoning Chai, Zelin Ye, Wenjing Xue, Shuqing Shi, Yi Wei, Yuanhui Hu, Huaqin Wu   +6 more
doaj   +1 more source

Alcoholic extracts of Russian sage (Salvia yangii) contain bioactive terpenoids with inhibitory activity against grapevine downy mildew (Plasmopara viticola)

Pest Management Science, EarlyView.
Alcoholic extracts from flowers, leaves, and shoots of Russian sage decreased downy mildew severity on grapevine leaf disks. Fractionation followed by metabolomic analysis revealed putative terpenoids as the main components of the active fractions. Specifically, 7‐methylrosmanol, 12‐O‐methylcarnosic acid, carnosic acid, and carnosol were identified as ...
Anna Smaldone, Oscar Giovannini, Martina Magni, Michael Oberhuber, Peter Robatscher, Michele Perazzolli   +5 more
wiley   +1 more source

Countercurrent chromatography in analytical chemistry (IUPAC technical report) [PDF]

, 2009
© 2009 IUPACCountercurrent chromatography (CCC) is a generic term covering all forms of liquid-liquid chromatography that use a support-free liquid stationary phase held in place by a simple centrifugal or complex centrifugal force field. Biphasic liquid
Abbey, Abe, Abe, Abe, Akiba, Akiba, Akiba, Alain Berthod, Bauer, Bauer, Berthod, Berthod, Berthod, Berthod, Berthod, Berthod, Billardello, Boris Spivakov, Chen, Chen, Chen, Chen, Chmutova, Chmutova, Chmutova, Conway, Conway, Conway, Countercurrent Chromatography, Dekker, Fedotov, Fitz, Friesen, Fujita, Garcia Dominguez, Hashimoto, Hashimoto, Ian A. Sutherland, Ikai, Ito, Ito, Ito, Ito, Ito, Jin, Jin, Jin, Kawamura, Kawamura, Kidwell, Kitazume, Kitazume, Kitazume, Kitazume, Kitazume, Kong, Lee, Lee, Lee, Lee, Liu, Ma, Ma, Mandava, Mandava, Marston, Marston, Marston, Maryutina, Maryutina, Maryutina, Maryutina, Maryutina, Matsuda, Menet, Muralidharan, Nakamura, Nakamura, Oleg Shpigun, Pauli, Pukhovskaya, Ruiz, Ruiz, Ruth, Schaufelberger, Schaufelberger, Schreiber, Shang, Spivakov, Spivakov, Spivakov, Stark, Sutherland, Tanaka, Tatyana Maryutina, Thurman, Tian, Usuda, Usuda, Wang, Wang, Watkins, Winterhalter, Wood, Wu, Yanagida, Yang, Yang, Yang, Yoshida, Yu, Zhang, Zhang   +112 more
core   +2 more sources

Modulation of Esterified Drug Metabolism by Tanshinones from Salvia miltiorrhiza (“Danshen”) [PDF]

Journal of Natural Products, 2013
The roots of Salvia miltiorrhiza ("Danshen") are used in traditional Chinese medicine for the treatment of numerous ailments including cardiovascular disease, hypertension, and ischemic stroke. Extracts of S. miltiorrhiza roots in the formulation "Compound Danshen Dripping Pill" are undergoing clinical trials in the United States.
M Jason, Hatfield, Lyudmila G, Tsurkan, Janice L, Hyatt, Carol C, Edwards, Andrew, Lemoff, Cynthia, Jeffries, Bing, Yan, Philip M, Potter   +7 more
openaire   +2 more sources

Content Determination and Chemical Clustering Analysis of Tanshinone and Salvianolic Acid in Salvia spp.

Metabolites
Salvia miltiorrhiza is one of the famous traditional Chinese medicines for treating cardiovascular and cerebrovascular diseases. Tanshinone and phenolic acids are the main active compounds of Salvia miltiorrhiza, whereas the distribution patterns of the ...
Feiyan Wang, Yufeng Bao, Furui Yang, Lu Yuan, Xinchun Han, Yanbo Huang, Yukun Wei, Lei Zhang, Zongqi Yang, Dongfeng Yang   +9 more
doaj   +1 more source

Proteolysis at the extracellular matrix interface: Molecular architects and regulators in health and disease

The FEBS Journal, EarlyView.
The extracellular matrix (ECM) is a dynamic scaffold that orchestrates tissue architecture and cellular communication. A critical but underexplored interplay between proteases and cluster of differentiation molecules (CD) governs ECM turnover and directs cell fate.
David Jurnečka, Matija Hrovatin, Bor Bokalj, Boris Turk   +3 more
wiley   +1 more source

Discovery of a Natural Syk Inhibitor from Chinese Medicine through a Docking-Based Virtual Screening and Biological Assay Study

Molecules, 2018
Spleen tyrosine kinase (Syk) is a critical target protein for treating immunoreceptor signalling-mediated allergies. In this study, a virtual screening of an in-house Chinese medicine database followed by biological assays was carried out to identify ...
Xing Wang, Junfang Guo, Zhongqi Ning, Xia Wu   +3 more
doaj   +1 more source

Climate change and crop resilience: harnessing metabolomics for predicting stress tolerance

New Phytologist, EarlyView.
Summarised methodology for metabolite biomarker discovery and genomic targets selection for those metabolites to predict high‐throughput phenotypic and agronomic traits of interest for direct uptake in breeding programmes. Summary Global warming is driving climate change to levels not experienced since the advent of agriculture, primarily due to ...
Agyeya Pratap, Arash Fazeli, Ali Bandehagh, Nicolas L. Taylor   +3 more
wiley   +1 more source

Herb Target Prediction Based on Representation Learning of Symptom related Heterogeneous Network. [PDF]

, 2019
Traditional Chinese Medicine (TCM) has received increasing attention as a complementary approach or alternative to modern medicine. However, experimental methods for identifying novel targets of TCM herbs heavily relied on the current available herb ...
Chen, Jianxin, Gao, Zhuye, Hu, Xiaochen, Li, Peng, Liu, Baoyan, Peng, Yonghong, Wang, Ning, Xu, Hao, Yang, Kuo, Zhang, Runshun, Zhou, Xuezhong, Zhu, Qiang   +11 more
core   +1 more source