Results 41 to 50 of about 7,870 (219)

Tanshinones induce tumor cell apoptosis via directly targeting FHIT

Scientific Reports, 2021
The liposoluble tanshinones are bioactive components in Salvia miltiorrhiza and are widely investigated as anti-cancer agents, while the molecular mechanism is to be clarified.
Xianglian Zhou, Yuting Pan, Yue Wang, Bojun Wang, Yu Yan, Yi Qu, Xisong Ke   +6 more
doaj   +1 more source

What Does It Take to Synergistically Combine Sub-Potent Natural Products into Drug-Level Potent Combinations? [PDF]

, 2012
10.1371/journal.pone.0049969PLoS ...
A Sivachenko, AL Harvey, B Fantin, B Papp, BA Larder, Chu Qin, Chun Yan Tan, CM Overall, Cun Long Zhang, Daniel S. Sem, DJ Newman, DM Eisenberg, DX Kong, EF Carvalho-Netto, EM Williamson, EW Sayers, F Zhu, F Zhu, FR Stermitz, GA Cordell, GG Zhang, GR Zimmermann, GT Lewith, GV Georgakis, H Quach, H Wagner, H Xiong, H Yang, HA Junio, HS Kim, J Gertsch, J Jia, J Kaiser, JE Dancey, JH MacIndoe, JI Johnson, JW Li, K Hayashi, Kai Leng Tan, KS Smalley, L Dinan, L Xie, LJ Li, LL Silver, M Shabbir, M Thanou, NV Sergina, P Csermely, PH Chiu, R Barker Bausell, R Muller, R Staud, RH Shoemaker, T Efferth, TC Chou, TF Molinski, TI Oprea, W Kassouf, X Tong, XH Ma, XM Zhou, Y Pilpel, Yu Yang Jiang, Yu Zong Chen   +63 more
core   +3 more sources

Functional Study and Efficient Catalytic Element Mining of CYP76AHs in Salvia Plants

Molecules, 2023
Salvia is a large genus with hundreds of species used in traditional Chinese medicine. Tanshinones are a highly representative class of exclusive compounds found in the Salvia genus that exhibit significant biological activity. Tanshinone components have
Zhenyu Zhao, Dongfeng Yang, Juan Guo, Xiuyu Liu, Qishuang Li, Ping Su, Jian Wang, Ying Ma, Luqi Huang   +8 more
doaj   +1 more source

Studies on polynuclear furoquinones. Part 1: Synthesis of tri- and tetra-cyclic furoquinones simulating BCD/ABCD ring system of furoquinone diterpenoids [PDF]

, 2009
Synthesis of phenanthro[1,2-b]furan-10,11-dione, the core nucleus present in Tanshinone-I is described in 8–10 steps starting from 2-bromo-3,4-dihydro-1-naphthaldehyde. The bromoaldehyde was converted to methyl 2-(2-bromo-1-naphthyl)acetate or 2-(2-bromo-
Fang, Duke, Mosaddik, Sung, Nakao, Takikura, Kakisawa, Baille, Teuber   +8 more
core   +1 more source

Advanced Technologies for Oral Controlled Release: Cyclodextrins for oral controlled release [PDF]

, 2011
Cyclodextrins (CDs) are used in oral pharmaceutical formulations, by means of inclusion complexes formation, with the following advantages for the drugs: (1) solubility, dissolution rate, stability and bioavailability enhancement; (2) to modify the drug ...
A Al-Omar, A Latrofa, A Miro, A Trapani, A Vyas, AC Jain, AK Upadhyay, AL Nielsen, AS Hoffman, B Haeberlin, B Pose-Vilarnovo, BN Naidu, C Cannavà, C Rodriguez-Tenreiro, C Rupp, C-Y Chen, Catarina Carvalho, Claúdia Conduto, CM Buchanan, CM Fernandes, D Duchêne, D Duchêne, EA Zannou, EY Kim, F Frézard, F Hirayama, G Corti, G Gladys, G Pescitelli, G Trapani, G Wenz, G Zingone, GL Amidon, H Blode, H Hamada, H Matsuda, H Namazi, H Taira, H Yano, HA Archontaki, Helena M. Cabral Marques, HH Sigurdsson, HS Ganapathy, HS Woldum, Inês Sanches, IV Terekhova, J Cheng, J Králová, J Savolainen, J Szejtli, J Szejtli, J Xiong, JJ García-Rodriguez, João Arrais, JP Venter, JR Moyano, JS Smith, JW Wong, K Dua, K Minami, K Motoyama, K Nakanishi, K Okimoto, K Okimoto, K Okimoto, K Terao, K Udo, K Uekama, K Uekama, K Uekama, K-H Frӧmming, KP Chowdary, L Ribeiro, L Szente, L Trichard, M Agüeros, M Agüeros, M Charoenchaitrakool, M Cirri, M Echezarreta-López, M Fukuda, M Jug, M Jug, M Kamada, M Prabaharan, M Roux, M Sauceau, M Temtem, M Türk, M Usuda, M Yoshinari, M-J Zou, ME Zugasti, MT Esclusa-Díaz, MZI Khan, N Mourtzis, N Patel, N Zerrouk, N Zhang, N Özdemir, P Jansook, P Mura, P Mura, P Mura, P Mura, P Mura, Patrícia Pontes, Paulo José Salústio, PJ Salústio, R Cavalli, R Cavalli, R Challa, R Ficarra, R Garg, R Stancanelli, RL Carrier, S Petralito, S Péroche, S Sajeesh, S Sotthivirat, S Sotthivirat, S Szejtli, S Tommasini, S-Y Lee, Shishu, SM Badr-Eldin, T Endo, T Higashi, T Higashi, T Irie, T Loftsson, T Loftsson, T Loftsson, T Vasconcelos, T Yamanoi, V Burckbuchler, V Lemesle-Lamache, VM Rao, W Ling, W Sajomsang, X Lu, X Wen, X-M Liu, Y He, Y Ikeda, Y Ikeda, Y Liu, Y Liu, Y Lu, Y Tozuka, Y Zhou, Y-Z Du, Z Lu, Z Wang   +153 more
core   +1 more source

Nitrogen Fertilization Improves Growth and Bioactive Compound Content for Salvia miltiorrhiza Bunge

Horticulturae, 2023
Salvia miltiorrhiza B., an herb used in traditional Chinese medicine, has been widely used to prevent and treat cardiovascular and other diseases. Currently, the majority of medicinal plants used in the US are imported from foreign countries, which ...
Zhiheng Xing, Guihong Bi, Tongyin Li, Qianwen Zhang, Patricia R. Knight   +4 more
doaj   +1 more source

Endothelin-1-induced hypertrophic alterations and heme oxygenase-1 expression in cardiomyoblasts are counteracted by beta estradiol: in vitro and in vivo studies [PDF]

, 2018
L
Balla, György, Barta, Tünde, Haines, David Donald, Lekli, István, Tósaki, Ágnes, Tósaki, Árpád   +5 more
core   +1 more source

Subcritical Water Extraction of Salvia miltiorrhiza

Molecules, 2021
In this work, a green extraction technique, subcritical water extraction (SBWE), was employed to extract active pharmaceutical ingredients (APIs) from an important Chinese medicinal herb, Salvia miltiorrhiza (danshen), at various temperatures.
Brahmam Kapalavavi, Ninad Doctor, Baohong Zhang, Yu Yang   +3 more
doaj   +1 more source

Chinese Medicines Induce Cell Death: The Molecular and Cellular Mechanisms for Cancer Therapy [PDF]

, 2014
published_or_final_versio
CHEUNG, F, Feng, Y, Kobayashi, S, Li, C, TAN, HY, Wang, N, Wang, X, Zhong, S   +7 more
core   +3 more sources

A Biomedical Investigation of the Hepatoprotective Effect of Radix salviae miltiorrhizae and Network Pharmacology-Based Prediction of the Active Compounds and Molecular Targets [PDF]

, 2017
published_or_final_versio
Cheung, F, Feng, Y, HONG, M, LI, S, Tan, HY, Wang, N   +5 more
core   +4 more sources