Results 41 to 50 of about 21,115,427 (202)

Tanshinones induce tumor cell apoptosis via directly targeting FHIT

Scientific Reports, 2021
The liposoluble tanshinones are bioactive components in Salvia miltiorrhiza and are widely investigated as anti-cancer agents, while the molecular mechanism is to be clarified.
Xianglian Zhou, Yuting Pan, Yue Wang, Bojun Wang, Yu Yan, Yi Qu, Xisong Ke   +6 more
doaj   +1 more source

Methyl Jasmonate Activates the 2C Methyl-D-erithrytol 2,4-cyclodiphosphate Synthase Gene and Stimulates Tanshinone Accumulation in Salvia miltiorrhiza Solid Callus Cultures

Molecules, 2022
The present study characterizes the 5′ regulatory region of the SmMEC gene. The isolated fragment is 1559 bp long and consists of a promoter, 5′UTR and 31 nucleotide 5′ fragments of the CDS region. In silico bioinformatic analysis found that the promoter
Piotr Szymczyk, Grażyna Szymańska, Łukasz Kuźma, Agnieszka Jeleń, Ewa Balcerczak   +4 more
doaj   +1 more source

Functional Study and Efficient Catalytic Element Mining of CYP76AHs in Salvia Plants

Molecules, 2023
Salvia is a large genus with hundreds of species used in traditional Chinese medicine. Tanshinones are a highly representative class of exclusive compounds found in the Salvia genus that exhibit significant biological activity. Tanshinone components have
Zhenyu Zhao, Dongfeng Yang, Juan Guo, Xiuyu Liu, Qishuang Li, Ping Su, Jian Wang, Ying Ma, Luqi Huang   +8 more
doaj   +1 more source

Discovery of tanshinone derivatives with anti-MRSA activity via targeted bio-transformation [PDF]

, 2016
Two potent anti-MRSA tanshinone glycosides (1 and 2) were discovered by targeted microbial biotransformation, along with rapid identification via MS/MS networking.
Houwei Luo, Jeramie D. Watrous, Zhang, Jingyu, Ronald J. Quinn, Jianying Han, Jingyu Zhang, Fuhang Song, Wang, Wenzhao, Luo, Houwei, Quinn, Ronald J, Watrous, Jeramie D., Dai, Huanqin, Abdel-Mageed, Wael M, Pei Huang, Liu, Miaomiao, Han, Jianying, Wael M. Abdel-Mageed, Tanja Grkovi, Watrous, Jeramie D, Zhang, Lixin, Grkovi, Tanja, Song, Fuhang, Quinn, Ronald J., Nguyen, Don D., Abdel-Mageed, Wael M., Wenni He, Lixin Zhang, Nguyen, Don D, Miaomiao Liu, Don D. Nguyen, Huanqin Dai, He, Wenni, Wenzhao Wang, Xueting Liu, Liu, Xueting, et al., Huang, Pei   +36 more
core   +1 more source

Nitrogen Fertilization Improves Growth and Bioactive Compound Content for Salvia miltiorrhiza Bunge

Horticulturae, 2023
Salvia miltiorrhiza B., an herb used in traditional Chinese medicine, has been widely used to prevent and treat cardiovascular and other diseases. Currently, the majority of medicinal plants used in the US are imported from foreign countries, which ...
Zhiheng Xing, Guihong Bi, Tongyin Li, Qianwen Zhang, Patricia R. Knight   +4 more
doaj   +1 more source

Hydroxylation of tanshinone IIa in human liver microsomes is specifically catalysed by cytochrome P4502A6

, 2009
Tanshinone IIa, the primary active component of a traditional Chinese medicine Salvia miltiorrhiza (Danshen), has a wide range of pharmacological activities.
Hu, Y., Li, W., 杨凌, He, Y. -Q., Liu, Y., Yang, L., Liu, H. -X.   +6 more
core   +1 more source

The one-pot modification of tanshinone mixture from Salvia miltiorrhiza.

, 2014
The one-pot modification of tanshinone mixture from Salvia miltiorrhiza.
Ai-Lin Liu (592284), Hai-Yan Tian (536638), Ren-Wang Jiang (448625), Shang Li (362882), Wen-Cai Ye (303536), Jin-Hang Li (592283), Pui-Man Hoi (592285), Simon Ming-Yuen Lee (545654), Zhe-Rui Zhang (592282)   +8 more
core   +1 more source

Subcritical Water Extraction of Salvia miltiorrhiza

Molecules, 2021
In this work, a green extraction technique, subcritical water extraction (SBWE), was employed to extract active pharmaceutical ingredients (APIs) from an important Chinese medicinal herb, Salvia miltiorrhiza (danshen), at various temperatures.
Brahmam Kapalavavi, Ninad Doctor, Baohong Zhang, Yu Yang   +3 more
doaj   +1 more source

Beyond Conventional: A Review of Phytochemical‐Hydrogel Systems Enhanced by AI and 3D Printing for Chronic Wound Management

Advanced Science, EarlyView.
This review systematically bridges chronic wound pathology with natural phytochemical hydrogel therapeutics. A pathology‐to‐phytochemical mechanistic mapping framework is established, linking specific wound hallmarks to targeted phytochemical interventions.
Yitao Zhou, Xing Liu, Cuiyi Wang, Xiaoxuan Zhao, Pengrun Zhang, Jingjing Gu, Qiuhua Sun, Malcolm Xing, Yeqin Yang   +8 more
wiley   +1 more source

The SmERF1b-like regulates tanshinone biosynthesis in Salvia miltiorrhiza hairy root

AoB PLANTS, 2023
Abstract The ethylene response factor family genes are involved in the regulation of secondary metabolism in Salvia miltiorrhiza, but the mechanism underlying this regulation remains elusive. In the present study, based on the cDNA library of S. miltiorrhiza, an AP2/ERF gene was cloned and named SmERF1b-like.
Li, Dan, Liu, Yu, Chen, Guoliang, Yan, Yan, Bai, Zhenqing   +4 more
openaire   +2 more sources