Results 71 to 80 of about 21,115,427 (202)

The regulation of stem cell fate and its application in neural regeneration

Interdisciplinary Medicine, Volume 4, Issue 5, September 2026.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He, Xingyu Chen, Minghong He, Zhe Li   +3 more
wiley   +1 more source

Tanshinone I Inhibits IL-1β-Induced Apoptosis, Inflammation And Extracellular Matrix Degradation In Chondrocytes CHON-001 Cells And Attenuates Murine Osteoarthritis

Drug Design, Development and Therapy, 2019
Xipeng Wang,1 Jianbo Fan,2 Xiaomin Ding,2 Yuyu Sun,2 Zhiming Cui,2 Wei Liu2 1Department of Orthopaedic Surgery, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430010, People’s Republic of
Wang X, Fan J, Ding X, Sun Y, Cui Z, Liu W   +5 more
doaj  

Tanshinone Content Prediction and Geographical Origin Classification of Salvia miltiorrhiza by Combining Hyperspectral Imaging with Chemometrics

Foods
Hyperspectral imaging (HSI) technology was combined with chemometrics to achieve rapid determination of tanshinone contents in Salvia miltiorrhiza, as well as the rapid identification of its origins.
Yaoyao Dai, Binbin Yan, Feng Xiong, Ruibin Bai, Siman Wang, Lanping Guo, Jian Yang   +6 more
doaj   +1 more source

Alcoholic extracts of Russian sage (Salvia yangii) contain bioactive terpenoids with inhibitory activity against grapevine downy mildew (Plasmopara viticola)

Pest Management Science, Volume 82, Issue 9, Page 8159-8170, September 2026.
Alcoholic extracts from flowers, leaves, and shoots of Russian sage decreased downy mildew severity on grapevine leaf disks. Fractionation followed by metabolomic analysis revealed putative terpenoids as the main components of the active fractions. Specifically, 7‐methylrosmanol, 12‐O‐methylcarnosic acid, carnosic acid, and carnosol were identified as ...
Anna Smaldone, Oscar Giovannini, Martina Magni, Michael Oberhuber, Peter Robatscher, Michele Perazzolli   +5 more
wiley   +1 more source

Tanshinone IIA stimulates erythrocyte phosphatidylserine exposure [PDF]

, 2012
Contains fulltext : 109681.pdf (Publisher’s version ) (Open Access)Tanshinone IIA, an antimicrobial, antioxidant, antianaphylactic, antifibrotic, vasodilating, antiatherosclerotic, organo-protective and antineoplastic component from the
Lang, F., Zelenak, C., Rosaclerio, L., Pasham, V., Qadri, S.M., Lupescu, A., Tripodi, P.M., Faggio, C., Jilani, K., Pathare, G.T.   +9 more
core   +2 more sources

Effects of tanshinone IIA on PASMCs proliferation under normoxic and hypoxic conditions.

, 2013
(A–B) Effects of tanshinone IIA on the proliferation of PASMCs under normoxic (21% O2) and hypoxic (3% O2) conditions. Hypoxia for 24 h significantly promoted PASMCs proliferation.
Yi Liu (36759), Wen Niu (381056), Dun-Quan Xu (381054), Ying Luo (381053), Zhi-Chao Li (381058), Ming-Qing Dong (381057), Bo Zhang (6559), Hai-Ying Dong (381055)   +7 more
core   +1 more source

Molecular Mechanism of Tanshinone against Prostate Cancer

, 2022
Prostate cancer (PCa) is the most common malignant tumor of the male urinary system in Europe and America. According to the data in the World Cancer Report 2020, the incidence rate of PCa ranks second in the prevalence of male malignant tumors and varies
Kaifa Tang, Bangwei Che, Che, Bangwei, Ying Yu, Li, Wei, Huang, Tao, Tao Huang, Zhang, Wenjun, Tang, Kaifa, Shenghan Xu, Wei Li, Xu, Shenghan, Wenjun Zhang, Yu, Ying   +13 more
core   +1 more source

Molecular descriptor driven QSPR modeling of Papp, TEER and Efflux Ratio from Caco‐2 cells using machine learning for various phytochemicals

Journal of the Science of Food and Agriculture, Volume 106, Issue 11, Page 6606-6616, 30 August 2026.
Abstract BACKGROUND The present study aimed to develop and validate quantitative structure–property relationship (QSPR) models for predicting permeability related bioavailability indicators including apparent permeability (Papp), trans‐epithelial electrical resistance (TEER) and efflux ratio (ER) based on molecular descriptors (n = 5003) of 83 ...
Jin‐Woo Kim, Rixing Cong, Jin‐Soo Park, Keunwan Park, Kyungsu Kang, Soon‐Mi Shim   +5 more
wiley   +1 more source

Proapoptotic and TRAIL-sensitizing constituents isolated from Salvia militiorrhiza (Danshen)

, 2014
Natural compounds isolated from medicinal plants are invaluable resources for drug discovery. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a promising anticancer agent unique by its cancer cell-specific proapoptotic action, but its ...
Chi-Shiuan Tsai, Liao, En-Chih, Ma, Song-Wei, Huang, Lan-Ru, Tsai, Chi-Shiuan, Chia-Che Chang, Chien-Hsing Lu, Lu, Chien-Hsing, Jyun-Yi Lin, Lai, Jui-Sheng, Tsing-Fen Ho, Ho, Tsing-Fen, Jui-Sheng Lai, Lan-Ru Huang, Chang, Chia-Che, En-Chih Liao, Lin, Jyun-Yi, Song-Wei Ma   +17 more
core   +1 more source

Unveiling Lactylation: A Novel Frontier in Cancer Stemness and Therapy

Advanced Science, Volume 13, Issue 46, 17 August 2026.
Tumor metabolism and epigenetic regulation are intrinsically linked. This review highlights lactylation as a pivotal bridge connecting these processes, acting as an active epigenetic effector in cancer stemness. We delineate how lactylation orchestrates the cancer stem cell landscape and evaluate its regulatory networks.
Ting Li, Hongyu Gu, Chang Liu, Yuesheng Lv, Feifei Li, Liang Liang, Jia Yi, Xuanyi Wang, Yi Zhun Zhu, Chuan Xu   +9 more
wiley   +1 more source