Results 131 to 140 of about 8,021 (203)

High-throughput cell-based compound screen identifies pinosylvin methyl ether and tanshinone IIA as inhibitors of castration-resistant prostate cancer [PDF]

, 2016
Current treatment options for castration-resistant prostate cancer (CRPC) are limited. In this study, a high-throughput screen of 4910 drugs and drug-like molecules was performed to identify antiproliferative compounds in androgen ablated prostate cancer
Culig, Zoran, Fey, Vidal, Iljin, Kristiina, Kallioniemi, Olli, Ketola, Kirsi, Kohonen, Pekka, Viitala, Miro   +6 more
core   +1 more source

Epigenetic Down-Regulation of Sirt 1 via DNA Methylation and Oxidative Stress Signaling Contributes to the Gestational Diabetes Mellitus-Induced Fetal Programming of Heart Ischemia-Sensitive Phenotype in Late Life. [PDF]

, 2019
Rationale: The incidence of gestational diabetes mellitus (GDM) is increasing worldwide. However, whether and how GDM exposure induces fetal programming of adult cardiac dysfunctional phenotype, especially the underlying epigenetic molecular mechanisms ...
Chen, Zewen, Gong, Lei, Li, Yong, Liu, Bailin, Xiao, Daliao, Zhang, Lubo, Zhang, Peng, Zhuang, Jian   +7 more
core  

Network Properties Revealed during Multi-Scale Calcium Imaging of Seizure Activity in Zebrafish. [PDF]

, 2019
Seizures are characterized by hypersynchronization of neuronal networks. Understanding these networks could provide a critical window for therapeutic control of recurrent seizure activity, i.e., epilepsy.
Baraban, Scott C, Liu, Jing
core   +1 more source

Analysis of the Constituents in Rat Serum after Oral Administration of Fufang Zhenzhu Tiaozhi Capsule by UPLC–Q–TOF–MS/MS [PDF]

, 2011
Xunlong Zhong, Jiao Guo, Laiyou Wang, Duosheng Luo, Weijian Bei, Yuanyuan Chen, Kangqi Yan, Junhui Peng   +7 more
core   +1 more source

Research progress on the molecular mechanisms of tanshinone IIA in the treatment of cardiovascular and cerebrovascular diseases (Review). [PDF]

Int J Mol Med
Pei W, Lu P, Ding C, Li Y, Li Y.
europepmc   +1 more source

Pharmacological Effects and Mechanisms of Tanshinone IIA in Bone Injury Repair. [PDF]

Pharmaceuticals (Basel)
Hu W, Si Y, Wen X, Lin D, Yu Z, Xie X, Xu J.   +6 more
europepmc   +1 more source

Tanshinone IIA prevents septicemia acute kidney injury via regulating the DUSP10/JNK/P38/NLRP3 pathway. [PDF]

Am J Transl Res
Wen D, Deng Q, Zeng Y, Li L, Yang X, Chen Q, Yan Y, Lv J.   +7 more
europepmc   +1 more source

Targeting Skp2 by Tanshinone IIA overcomes chemoresistance in colorectal cancer. [PDF]

Cell Biol Toxicol
Dong X, Li K, Wang R, Wei B, Li Y, Zhang Y, Huang S, Wang G, Gao Q, Li W, Cui W.   +10 more
europepmc   +1 more source

Protective effect of tanshinone IIA against Listeria monocytogenes infection in vitro and in vivo. [PDF]

Sci Rep
Wang H, Hu S, Feng H, Sun H.
europepmc   +1 more source

Tanshinone IIA alleviates LPS-induced acute kidney injury by inhibiting RIP3/Nrf2-mediated oxidative stress. [PDF]

Ren Fail
Zhang S, Dong X, Chen G, Wang C.
europepmc   +1 more source