Results 201 to 210 of about 116,988 (242)
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Phytomedicine
BACKGROUND Melanoma is highly aggressive, metastatic with a poor prognosis. Despite significant advances in targeted therapies and immunotherapies, their efficiency limited by drug resistance.
Shuyue Chen +9 more
semanticscholar +1 more source
BACKGROUND Melanoma is highly aggressive, metastatic with a poor prognosis. Despite significant advances in targeted therapies and immunotherapies, their efficiency limited by drug resistance.
Shuyue Chen +9 more
semanticscholar +1 more source
Journal of Ethnopharmacology, 2023
ETHNOPHARMACOLOGICAL RELEVANCE Chronic intermittent hypoxia (CIH) is the primary pathophysiological process of obstructive sleep apnea (OSA) and is closely linked to neurocognitive dysfunction.
Jianchao Si +6 more
semanticscholar +1 more source
ETHNOPHARMACOLOGICAL RELEVANCE Chronic intermittent hypoxia (CIH) is the primary pathophysiological process of obstructive sleep apnea (OSA) and is closely linked to neurocognitive dysfunction.
Jianchao Si +6 more
semanticscholar +1 more source
International Journal of Biological Macromolecules, 2023
Persistent bacterial infection caused by biofilms is one of the most serious problems that threatened human health. The development of antibacterial agents remains a challenge to penetrate biofilm and effectively treat the underlying bacterial infection.
Ming-Xia Wang +4 more
semanticscholar +1 more source
Persistent bacterial infection caused by biofilms is one of the most serious problems that threatened human health. The development of antibacterial agents remains a challenge to penetrate biofilm and effectively treat the underlying bacterial infection.
Ming-Xia Wang +4 more
semanticscholar +1 more source
International Immunopharmacology
OBJECTIVES Tanshinone IIA (Tan IIA) exhibits therapeutic potential for atherosclerosis (AS) and hepatic steatosis (HS). The study aims to explore the mechanisms underlying the anti-atherosclerosis and anti-hepatic steatosis effects of Tan IIA.
Yifan Zhang +4 more
semanticscholar +1 more source
OBJECTIVES Tanshinone IIA (Tan IIA) exhibits therapeutic potential for atherosclerosis (AS) and hepatic steatosis (HS). The study aims to explore the mechanisms underlying the anti-atherosclerosis and anti-hepatic steatosis effects of Tan IIA.
Yifan Zhang +4 more
semanticscholar +1 more source
Neurotoxicology
OBJECTIVE Postoperative cognitive dysfunction (POCD) is a common and debilitating complication in elderly patients following surgery, leading to increased morbidity and reduced quality of life.
Yan Yang, Bo Wang, Yi-Chen Jiang, Wan Fu
semanticscholar +1 more source
OBJECTIVE Postoperative cognitive dysfunction (POCD) is a common and debilitating complication in elderly patients following surgery, leading to increased morbidity and reduced quality of life.
Yan Yang, Bo Wang, Yi-Chen Jiang, Wan Fu
semanticscholar +1 more source
Preparation and physicochemical characterizations of tanshinone IIA solid dispersion
Archives of Pharmacal Research, 2011This investigation describes a novel approach to prepare solid dispersions of tanshinone IIA using a laboratory-scale planetary ball mill. Poloxamer 188 was employed as the surfactant carrier to improve the solubility and dissolution of the poorly soluble drug, tanshinone IIA.
Xia, Zhao +4 more
openaire +2 more sources
Toxicology Letters, 2023
Danshen Si Wu is a Traditional Chinese Medicine used for menopausal complains. Beside tanshinone IIA (Tan IIA), Danshen also contains tanshinone I (Tan I), cryptotanshinone (CT) and dihydrotanshinone (DT). The aim of this study was to compare the biological activity of these tanshinones and to determine their cytotoxicity and genotoxicity. Purities and
Annika, Roth +6 more
openaire +2 more sources
Danshen Si Wu is a Traditional Chinese Medicine used for menopausal complains. Beside tanshinone IIA (Tan IIA), Danshen also contains tanshinone I (Tan I), cryptotanshinone (CT) and dihydrotanshinone (DT). The aim of this study was to compare the biological activity of these tanshinones and to determine their cytotoxicity and genotoxicity. Purities and
Annika, Roth +6 more
openaire +2 more sources
The Journal of Periodontology
Periodontitis is a chronic inflammatory condition that leads to progressive destruction of the alveolar bone. Currently, there is a lack of effective adjuvant treatments to nonsurgical periodontal therapy offering strong antiresorptive properties ...
A. L. R. Pavanelli +7 more
semanticscholar +1 more source
Periodontitis is a chronic inflammatory condition that leads to progressive destruction of the alveolar bone. Currently, there is a lack of effective adjuvant treatments to nonsurgical periodontal therapy offering strong antiresorptive properties ...
A. L. R. Pavanelli +7 more
semanticscholar +1 more source
International Journal of Biological Macromolecules, 2023
In Alzheimer's disease (AD), amyloid-beta (Aβ) plays a crucial role in pathogenesis. Clearing Aβ from the brain is considered as a key therapeutic strategy. Previous studies indicated that Salvia miltiorrhiza (Danshen) could protect against AD.
Xiao-qi Liu +6 more
semanticscholar +1 more source
In Alzheimer's disease (AD), amyloid-beta (Aβ) plays a crucial role in pathogenesis. Clearing Aβ from the brain is considered as a key therapeutic strategy. Previous studies indicated that Salvia miltiorrhiza (Danshen) could protect against AD.
Xiao-qi Liu +6 more
semanticscholar +1 more source
Medicine
This study explores the mechanism of action of tanshinone IIA in the treatment of chronic obstructive pulmonary disease (COPD) using network pharmacology and molecular docking.
Huaiquan Liu +4 more
semanticscholar +1 more source
This study explores the mechanism of action of tanshinone IIA in the treatment of chronic obstructive pulmonary disease (COPD) using network pharmacology and molecular docking.
Huaiquan Liu +4 more
semanticscholar +1 more source