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Preparation, Characterization Evaluation of Tanshinone IIA Lipid Microspere and Comparative Study of Pharmacokinetics with Sodium Tanshinone IIA Sulfonate Injection

Advanced Materials Research, 2013
In this study, Tanshinone IIA lipid microspere (Tan-IIA-LM) was successfully prepared by an ultrasonic and high-pressure homogenization method. The particle size, zeta potential, drug entrapment efficiency and morphological properties of Tan-IIA-LM were characterized in detail.
Xin Li Liang   +6 more
openaire   +1 more source

[Study on the chemical stability of tanshinone IIA].

Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials, 2011
To investigate the chemical kinetics of tanshinone IIA in different conditions quantitatively and calculate the chemical kinetic parameters and equations in order to find out the major factors affecting the stability of tanshinone IIA.The kinetic line was obtained by setting the ln (C(t)/C0) as ordinate and making time as abscissa.
Mei, Liu, Xin-Hua, Xia
openaire   +1 more source

Tanshinone IIA and tanshinone I production by Trichoderma atroviride D16, an endophytic fungus in Salvia miltiorrhiza

Phytomedicine, 2012
In this study the isolation of an endophytic fungus from the root of the medicinal herb Salvia miltiorrhiza Bunge is reported for the first time. The fungus produced tanshinone I and tanshinone IIA in rich mycological medium (potato dextrose broth) under shake flask and bench scale fermentation conditions.
Qianliang, Ming   +8 more
openaire   +2 more sources

Endothelial TRPV4 channel mediates the vasodilation induced by Tanshinone IIA

Chemico-Biological Interactions
Tanshinone IIA (TSA), the main lipo-soluble component from the dried rhizome of Salvia miltiorrhiza, has been shown to induce vasodilation. However, the underlying mechanisms remains unclear. This study aimed to investigate the effect of TSA on the vasodilation of small resistant arteries ex vivo. Vascular myography revealed that endothelial denudation
Pei Wang   +8 more
openaire   +2 more sources

Effects of tanshinone IIA on endothelial cell dysfunction in uremic condition

Journal of Biochemical and Molecular Toxicology
AbstractAn arteriovenous fistula (AVF) is the preferred vascular access for hemodialysis in uremic patients, yet its dysfunction poses a significant clinical challenge. Venous stenosis, primarily caused by venous neointimal hyperplasia, is a key factor in the failure of vascular access.
Li‐hua Wang   +5 more
openaire   +2 more sources

Tanshinone IIA, Curcumin, and Rutin Phytotherapy

2023
Rajesh Kumar   +4 more
openaire   +1 more source

Tanshinone IIA

2018
Yu-Cai Chen, Lian-Hua Fang, Guan-Hua Du
openaire   +1 more source

<p>Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases</p>

Drug Design, Development and Therapy, 2020
Guanwei Fan, Rui Guo, Zhihao Liu
exaly  

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