Results 231 to 240 of about 819,635 (326)

Deacetylation of BAP31 by sirtuin 2 attenuates apoptosis of hepatocytes induced by endoplasmic reticulum stress, in chronic alcoholic liver injury

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Endoplasmic reticulum (ER) stress is a crucial pathogenic mechanism in alcoholic liver disease (ALD). B‐cell receptor‐associated protein 31 (BAP31) can regulate ER homeostasis and anti‐apoptosis, but the function and regulation of BAP31 in ALD are unclear.
Sai Wang, Yufeng Wang, Wen Shan, Guoyang Li, Ran Yan, Zhecheng Wang, Yan Zhao, Jihong Yao, Ning Zhang   +8 more
wiley   +1 more source

Protocol for forming G-quadruplexes from double-stranded DNA during transcription. [PDF]

STAR Protoc
Zhang J, Gong J, Chen J, Chen H.
europepmc   +1 more source

Characterisation of neurogenic lipolytic responses in white adipose tissue ex vivo

British Journal of Pharmacology, Volume 182, Issue 9, Page 1975-1988, May 2025.
Background and Purpose Dysfunction of the autonomic nervous system is associated with cardiovascular dysfunction, including metabolic syndrome and obesity. Understanding mechanisms of neurogenic control of white adipose tissue is key to understanding adipose physiology and pathophysiology, though there is limited research exploring this in adipose ...
Kayleigh E. Goddard, Samuel J. Fountain
wiley   +1 more source

Effect of transition metal ions on the fluorescence and Taq-catalyzed polymerase chain reaction of tricyclic cytidine analogs [PDF]

, 2011
Gudrun Stengel, Byron W. Purse, Robert D. Kuchta   +2 more
openalex   +1 more source

Impact of Minimal Residual Disease on Early Recurrence of Liver Metastatic Colorectal Cancer

Cancer Science, Volume 116, Issue 5, Page 1366-1374, May 2025.
Our study highlights the significant role of minimal residual desease(MRD) assessment in patients with reseble CRLM, particularly in predicting early recurrence and guiding treatement decisions, suggesting that adjuvant chemotherapy may not offer substantial benefits for MRD‐negative patients.
Mampei Kawashima, Takeshi Yamada, Toshimitsu Miyasaka, Shintaro Kanaka, Sho Kuriyama, Kay Uehara, Akihisa Matsuda, Ryo Ohta, Hiromichi Sonoda, Nobuhiko Taniai, Hiroshi Yoshida   +10 more
wiley   +1 more source

One-Step Multiplex RT-PCR Method for Detection of Melon Viruses. [PDF]

Microorganisms
Han S, Zhou T, Zhang F, Feng J, Han C, Maimaiti Y.   +5 more
europepmc   +1 more source

Single‐Nucleus RNA Sequencing and Spatial Transcriptomics for Squamous Cell Carcinoma Arising From Ovarian Mature Teratoma

Cancer Science, Volume 116, Issue 5, Page 1339-1351, May 2025.
Single‐nucleus RNA‐seq identified KLF5 as an upregulated gene in SCC‐MT cells. Spatial transcriptomics showed inhibited EMT in SCC‐MT cells. KLF5 downregulation reduced SCC‐MT cell proliferation and increased apoptosis. ABSTRACT Squamous cell carcinoma arising from mature teratoma (SCC‐MT) is a rare ovarian malignancy.
Kosuke Yoshida, Akira Yokoi, Hironori Suzuki, Satoshi Tamauchi, Masami Kitagawa, Eri Inami, Jun Nakayama, Yutaro Mori, Koji Okamoto, Yutaka Suzuki, Hiroshi Yoshida, Tomoyasu Kato, Hiroaki Kajiyama, Yusuke Yamamoto   +13 more
wiley   +1 more source

Strategies and procedures to generate chimeric DNA polymerases for improved applications. [PDF]

Appl Microbiol Biotechnol
Yu Z, Wang J.
europepmc   +1 more source

Production and Functional Verification of 8‐Gene (GGTA1, CMAH, β4GalNT2, hCD46, hCD55, hCD59, hTBM, hCD39)‐Edited Donor Pigs for Xenotransplantation

Cell Proliferation, EarlyView.
Schematic representation of generation of 8‐gene‐edited cloned pigs and their verification by pig to non‐human primate kidney xenotransplantation. ABSTRACT Gene‐edited (GE) pig‐to‐human xenotransplantation continues to make breakthroughs, but which kind of gene combination is suitable for organ‐specific transplantation remains unclear.
Jiaoxiang Wang, Kaixiang Xu, Tao Liu, Heng Zhao, Muhammad Ameen Jamal, Gen Chen, Xiaoying Huo, Chang Yang, Deling Jiao, Taiyun Wei, Hanfei Huang, Hongfang Zhao, Jianxiong Guo, Fengchong Wang, Xiong Zhang, Kai Liu, Siming Qu, Gang Wang, Hui Guo, Gang Chen, Hong‐Ye Zhao, Zhong Zeng, Kefeng Dou, Hong‐Jiang Wei   +23 more
wiley   +1 more source

The use of Taq DNA polymerase to determine the sequence specificity of DNA damage caused by cis-diamminedichloroplatinum(II), acridine-tethered platinum(II) diammine complexes or two analogues.

, 1992
Vincent Murray, Halina Motyka, Phillip R. England, Geoffrey Wickham, Hae‐Hyeog Lee, William A. Denny, W. David McFadyen   +6 more
openalex   +1 more source