Results 241 to 250 of about 819,635 (326)

RNF187 Facilitates Proliferation and Migration of Human Spermatogonial Stem Cells Through WDR77 Polyubiquitination

open access: yesCell Proliferation, EarlyView.
RNF187 mediates the polyubiquitination and subsequent degradation of WDR77, reduces H4R3me2s catalysed by the WDR77/PRMT5 complex, and derepresses the transcription of EGR1, thereby promoting the proliferation and migration of human SSCs. ABSTRACT The E3 ubiquitin ligase RNF187, also known as RING domain AP1 coactivator‐1, is a member of the RING ...
Haoyue Hu   +12 more
wiley   +1 more source

16S rRNA amplicon sequencing of organic and conventional chickens. [PDF]

open access: yesMicrobiol Resour Announc
Punchihewage-Don AJ   +2 more
europepmc   +1 more source

Hypertranscription of rDNA Responsible for Nucleolar Remodelling is a Doorman for Acquiring Pluripotency

open access: yesCell Proliferation, EarlyView.
Active nucleoli have the capability to release perinuclear heterochromatin, which is a novel event of iPSC reprogramming. ABSTRACT Ribosome biogenesis occurs within the nucleolus, with the initial step being the transcription of ribosomal DNA (rDNA). Although rDNA transcription is limited in somatic cells, it is more active in stem cells. Nevertheless,
Yuchen Sun   +7 more
wiley   +1 more source

Neural Organoids Protect Engineered Heart Tissues From Glucolipotoxicity by Transferring Versican in a Co‐Culture System

open access: yesCell Proliferation, EarlyView.
In this study, Bai et al. established a co‐culture system between neural organoids (NOs) and engineered heart tissues (EHTs) and demonstrated that NOs could secrete versican, which was absorbed by EHTs to ameliorate glucolipotoxicity. ABSTRACT Metabolic disorders could cause dysregulated glucose and lipid at the systemic level, but how inter‐tissue ...
Baochen Bai   +22 more
wiley   +1 more source

Deaminase-driven random mutation enables efficient DNA mutagenesis for protein evolution. [PDF]

open access: yesChem Sci
Hao Y   +11 more
europepmc   +1 more source

Transcriptional response in larvae of the generalist fruit fly Anastrepha obliqua feeding on three different tropical host plants

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We investigated the molecular basis of host switching by the phytophagous West Indian fruit fly (A. obliqua). Third‐instar larvae showed differential gene expression according to host plants: red mombin, mango, and carambola. The main gene categories differentially expressed were digestion, detoxification, and gene regulators.
Sandra M. Velasco‐Cuervo   +5 more
wiley   +1 more source

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