Results 51 to 60 of about 6,075,366 (305)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Rhizomatic Target Audiences of the Cyber Domain

open access: yes, 2016
Target Audience Analysis (TAA) is a process of finding suitable target audiences for psychological operations (PSYOPS). Typically, a TAA is a one-way process with some kind of a feedback system.
Huhtinen, Aki-Mauri   +2 more
core   +1 more source

Synthetic Source Universal Domain Adaptation through Contrastive Learning

open access: yesSensors, 2021
Universal domain adaptation (UDA) is a crucial research topic for efficient deep learning model training using data from various imaging sensors. However, its development is affected by unlabeled target data. Moreover, the nonexistence of prior knowledge
Jungchan Cho
doaj   +1 more source

Combining in-domain and out-of-domain speech data for automatic recognition of disordered speech [PDF]

open access: yes, 2013
Recently there has been increasing interest in ways of using out-of-domain (OOD) data to improve automatic speech recognition performance in domains where only limited data is available.
Bell, P.   +6 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Generalized Zero-Shot Domain Adaptation for Unsupervised Cross-Domain PolSAR Image Classification

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2022
Cross-domain polarimetric synthetic aperture radar interpretation is urgently needed, due to the rapid data growth and label scarcity. However, the class distribution shift problems hinder the reuse of labeled samples among cross-domain images.
Rong Gui   +4 more
doaj   +1 more source

Radar target micro-doppler signature classification [PDF]

open access: yes, 2008
This thesis reports on research into the field of Micro-Doppler Signature (μ-DS) based radar Automatic Target Recognition (ATR) with additional contributions to general radar ATR methodology.
Smith, G.E.
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

On the Metaphorics of Sweets and Meats

open access: yesStyles of Communication, 2016
This paper is aimed to be a contribution to the study of foodsemy, that is one of the recently much studied subtypes of metaphorical transfer where the source category are lexical items related to the category FOODSTUUFS while the target domain is the ...
Grzegorz A. Kleparski
doaj  

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