Results 51 to 60 of about 22,090 (255)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Ion‐Pair‐Tuned Ionogels for Broad‐Range Linear Pressure Sensing

Advanced Science, EarlyView.
Ionogels engineered through ion‐pair tuning extend the linear sensing range of capacitive pressure sensors. By balancing ionic mobility and polarizability within the polymer matrix, this approach mitigates dielectric saturation and maintains a stable pressure response across a broad operating range.
Hyeonseo Joo, Tianhao Yu, Yumin Dai, Seokkyoon Hong, Axel González Cornejo, Tristan Michael Long, Sang Mok Park, Pete S. Kollbaum, Edgar Bolívar‐Nieto, Young L. Kim, Dong Rip Kim, Chi Hwan Lee   +11 more
wiley   +1 more source

CXCR3 antagonism of SDF-1(5-67) restores trabecular function and prevents retinal neurodegeneration in a rat model of ocular hypertension. [PDF]

PLoS ONE, 2012
Glaucoma, the most common cause of irreversible blindness, is a neuropathy commonly initiated by pathological ocular hypertension due to unknown mechanisms of trabecular meshwork degeneration.
Alexandre Denoyer, David Godefroy, Isabelle Célérier, Julie Frugier, Julie Degardin, Jeffrey K Harrison, Francoise Brignole-Baudouin, Serge Picaud, Francoise Baleux, José A Sahel, William Rostène, Christophe Baudouin   +11 more
doaj   +1 more source

Liquid Metals in Radio Frequency Applications: A Review of Physics, Manufacturing, and Emerging Technologies

Advanced Electronic Materials, EarlyView.
This paper reviews the physics of liquid metals in RF devices, including the influence of mechanical strain on resonance as well as fabrication methods and strategies for designing tunable and strain‐tolerant inductors, capacitors, and antennas.
Md Saifur Rahman, William J. Scheideler
wiley   +1 more source

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

The trabecular bypass stent in a pseudophakic glaucoma patient: A 1-year follow-up

Clinical Ophthalmology, 2008
Antonio M Fea, Monica Dogliani, Federica Machetta, Gabriella Lale-Lacroix, Beatrice Brogliatti, Federico MGrignoloIstituto di Fisiopatologia Clinica, Clinica Oculistica, Università di Torino, ItalyPurpose: To describe the 1-year success of a ...
Antonio M Fea, Monica Dogliani, Federica Machetta, Gabriella Lale-Lacroix, Beatrice Brogliatti, Federico MGrignolo   +5 more
doaj  

In vivo imaging of structural, metabolic and functional brain changes in glaucoma

Neural Regeneration Research, 2019
Glaucoma, the world’s leading cause of irreversible blindness, is a condition for which elevated intraocular pressure is currently the only modifiable risk factor. However, the disorder can continue to progress even at reduced intraocular pressure.
Anisha Kasi, Muneeb A. Faiq, Kevin C. Chan   +2 more
doaj   +1 more source

Glaucoma-causing myocilin mutants require the Peroxisomal targeting signal-1 receptor (PTS1R) to elevate intraocular pressure [PDF]

Human Molecular Genetics, 2007
Glaucoma is a leading cause of worldwide irreversible visual impairment and blindness and is a clinically and genetically heterogenous group of optic neuropathies. Specific mutations in the myocilin (MYOC) gene cause primary open angle glaucoma (POAG) with varying age-of-onset and degree of severity.
Allan R, Shepard, Nasreen, Jacobson, J Cameron, Millar, Iok-Hou, Pang, H Thomas, Steely, Charles C, Searby, Val C, Sheffield, Edwin M, Stone, Abbot F, Clark   +8 more
openaire   +2 more sources

Microrobotic Catheterization of the Ophthalmic Artery for Targeted Treatment of Retinoblastoma

Advanced Intelligent Systems, EarlyView.
A microrobotic platform is presented that allows teleoperated and autonomous navigation of flow‐driven magnetic microcatheters, MagFlow, into the ophthalmic artery for superselective intra‐arterial infusion of chemotherapy to treat retinoblastoma. Extensive benchtop validations with patient‐derived biomimetic phantoms under optical and fluoroscopic ...
Artur Banach, Mehdi Krichen, Julian Raub, Christina Stathopoulos, Bruno Bartolini, Mahmut Selman Sakar   +5 more
wiley   +1 more source

Long-term efficacy and safety of ab externo canaloplasty in the Polish Caucasian population with open-angle glaucoma: A 3-year retrospective study.

PLoS ONE
This study aimed to assess the effectiveness and safety of ab externo canaloplasty over a 3-year follow-up period in Polish Caucasian patients with glaucoma.
Joanna Konopińska, Kinga Gołaszewska, Emil Saeed   +2 more
doaj   +1 more source