Results 1 to 10 of about 2,384,470 (249)

Design and Experimental Verification of Targeted and Variable Sprayer for the Potato

open access: yesAgriculture, 2023
For potatoes, a crop with a specific plant spacing and a large row spacing, continuous spray has problems including low spraying accuracy and washability.
Longfei Li   +4 more
doaj   +1 more source

Unravelling Plant Responses to Stress—The Importance of Targeted and Untargeted Metabolomics

open access: yesMetabolites, 2021
Climate change and an increasing population, present a massive global challenge with respect to environmentally sustainable nutritious food production.
James William Allwood   +6 more
doaj   +1 more source

1H-NMR metabolomics for wine screening and analysis

open access: yesOENO One, 2023
The number of metabolomic studies has grown steadily over the last twenty years. Among the fields of application, food sciences are broadly represented.
Inès Le Mao   +2 more
doaj   +1 more source

The “SEED” Study: The Feasibility of Selecting Patient-Specific Biologically Targeted Therapy with Sorafenib, Everolimus, Erlotinib or Dasatinib for Pediatric and Young Adult Patients with Recurrent or Refractory Brain Tumors

open access: yesFrontiers in Bioscience-Landmark, 2022
Background: Pediatric brain tumors are the leading cause of cancer death in children and represent a variety of diseases and molecular subtypes. This study sought to evaluate a rapid immunohistochemistry testing panel to aid in therapy selection at the ...
Bonnie L. Cole   +3 more
doaj   +1 more source

How to Start Up a National Wildlife Health Surveillance Programme

open access: yesAnimals, 2021
Whilst multiple countries in Europe have wildlife health surveillance (WHS) programmes, they vary in scope. In many countries, coordinated general surveillance at a national scale is not conducted and the knowledge of wildlife health status in Europe ...
Becki Lawson   +12 more
doaj   +1 more source

Targeted treatment of solid tumors in pediatric precision oncology

open access: yesFrontiers in Oncology, 2023
The treatment of childhood solid cancer has markedly evolved in recent years following a refined molecular characterization and the introduction of novel targeted drugs.
Ilaria Bertacca   +5 more
doaj   +1 more source

Covalent conjugation of extracellular vesicles with peptides and nanobodies for targeted therapeutic delivery

open access: yesJournal of Extracellular Vesicles, 2021
Natural extracellular vesicles (EVs) are ideal drug carriers due to their remarkable biocompatibility. Their delivery specificity can be achieved by the conjugation of targeting ligands.
Tin Chanh Pham   +19 more
doaj   +1 more source

Dramatic Therapeutic Response to Dabrafenib Plus Trametinib in BRAF V600E Mutated Papillary Craniopharyngiomas: A Case Report and Literature Review

open access: yesFrontiers in Medicine, 2022
BackgroundCraniopharyngioma is a rare intracranial tumor, with a high morbidity rate due to its common refractiveness to conventional treatments. BRAF V600E mutation has recently been identified as the principal oncogenic molecular driver of papillary ...
Morena Fasano   +9 more
doaj   +1 more source

Aptamers as Smart Ligands for Targeted Drug Delivery in Cancer Therapy

open access: yesPharmaceutics, 2022
Undesirable side effects and multidrug tolerance are the main holdbacks to the treatment of cancer in conventional chemotherapy. Fortunately, targeted drug delivery can improve the enrichment of drugs at the target site and reduce toxicity to normal ...
Zongyi Wei   +4 more
doaj   +1 more source

Poly-α, β-d, l-Aspartyl-Arg-Gly-Asp-Ser-Based Urokinase Nanoparticles for Thrombolysis Therapy

open access: yesMolecules, 2023
The most concerning adverse effects of thrombolytic agents are major bleeding and intracranial hemorrhage due to their short half-life, low fibrin specificity, and high dosage.
Shuangling Chen   +5 more
doaj   +1 more source

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