Results 251 to 260 of about 653,941 (306)

Nanothermometry in Living Cells: Physical Limits, Conceptual and Material Challenges

Advanced Functional Materials, EarlyView.
Heat and temperature are fundamental to life. When nanothermometers began probing regions as small as a living cell, they triggered controversial claims of large intracellular temperature gradients. We review physical constraints energy‐conservation, entropy production, thermodynamic fluctuations, and molecular dynamics.
Taras Plakhotnik
wiley   +1 more source

Acoustically activatable liposomes as a translational nanotechnology for site-targeted drug delivery and noninvasive neuromodulation. [PDF]

Nat Nanotechnol
Purohit MP, Yu BJ, Roy KS, Xiang Y, Ewbank SN, Azadian MM, Hart AR, Muwanga GPB, Martinez PJ, Wang JB, Taoube AK, Markarian E, Macedo N, Kwan AK, Lopez DG, Airan RD.   +15 more
europepmc   +1 more source

Harnessing Extracellular Vesicles for Targeted Drug Delivery in Ovarian Cancer. [PDF]

Pharmaceutics
Yun JH, Noh YR, Yoo S, Park S, Choi Y, An J, Kim I.   +6 more
europepmc   +1 more source

Nanotechnology in leukemia therapy: revolutionizing targeted drug delivery and immune modulation. [PDF]

Clin Exp Med
Bishoyi AK, Nouri S, Hussen A, Bayani A, Khaksari MN, Soleimani Samarkhazan H.   +5 more
europepmc   +1 more source

Biodegradable Zwitterionic PLA-Based Nanoparticles: Design and Evaluation for pH-Responsive Tumor-Targeted Drug Delivery. [PDF]

Polymers (Basel)
Christodoulou E, Tsimpolis A, Theodorakis K, Axypolitou S, Tsamesidis I, Kontonasaki E, Pavlidou E, Bikiaris DN.   +7 more
europepmc   +1 more source

Dual-phoretic wireless device for directionally oriented and carrier-free targeted drug delivery. [PDF]

Sci Adv
Choi SG, Kim S, Kim JW, Choi MK, Han J, Koo DJ, Lee SH, Kim A, Gu JW, Kim KH, Lee JY, Bae JY, Kim SY, Kim J, Lee H, Kang SK.   +15 more
europepmc   +1 more source

Correction to [Synthetic Biomimetic Liposomes Harness Efferocytosis Machinery for Highly Efficient Macrophages-Targeted Drug Delivery to Alleviate Inflammation]. [PDF]

Adv Sci (Weinh)
europepmc   +1 more source

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Targeted drug delivery

Cancer, 1986
Cancer chemotherapy drugs are neither specific, i.e., they do not act exclusively on the metabolic pathways of cancer cells, nor are they targeted solely toward cancer cells. However, recent research has begun to address, in part, the latter issue. Improved delivery of chemotherapeutic agents to tumor tissue in man appears to be an achievable goal in ...
A I, Freeman, E, Mayhew
openaire   +2 more sources

Ligand-Targeted Drug Delivery

Chemical Reviews, 2017
Safety and efficacy constitute the major criteria governing regulatory approval of any new drug. The best method to maximize safety and efficacy is to deliver a proven therapeutic agent with a targeting ligand that exhibits little affinity for healthy cells but high affinity for pathologic cells.
Madduri Srinivasarao, Philip S. Low
openaire   +2 more sources

Targeted drug delivery

Expert Opinion on Therapeutic Patents, 1999
Creating effective targeted drug delivery strategies is an integral component of the overall process of drug development. The four key requirements of an effective drug delivery system are retain, evade, target and release. Increasing the therapeutic index (TI) of a delivered compound by selectively delivering it to target areas is a goal that has many
Jeffrey K Mills, David Needham
openaire   +2 more sources