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Targeted drug delivery to melanoma
Advanced Drug Delivery Reviews, 2018Melanoma derived from melanocytes is the most aggressive genre of skin cancer. Although the considerable advancement in the study of human cancer biology and drug discovery, most advanced melanoma patients are inevitably unable to be cured. With the emergence of nanotechnology, the use of nano-carriers is widely expected to alter the landscape of ...
Das, Manisit +3 more
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Alginate Nanoparticles for Drug Delivery and Targeting
Current Pharmaceutical Design, 2019Nanotechnology refers to the control, manipulation, study and manufacture of structures and devices at the nanometer size range. The small size, customized surface, improved solubility and multi-functionality of nanoparticles will continue to create new biomedical applications, as nanoparticles allow to dominate stability, solubility and ...
Severino, Patricia +5 more
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Physics in Technology, 1985
Conventional forms of drugs normally medicate the whole body, reaching healthy areas as well as diseased. However techniques are now available which are better at restricting drug action to the sites where it is needed.
A T Florence, G W Halbert
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Conventional forms of drugs normally medicate the whole body, reaching healthy areas as well as diseased. However techniques are now available which are better at restricting drug action to the sites where it is needed.
A T Florence, G W Halbert
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Drug Targets, Drug Effectors, and Drug Targeting and Delivery
2012The chemotherapy of leishmaniases has undergone significant improvements during the last decade with the use of liposomal amphotericin B formulation (AmBisome®) and miltefosine as the first orally active drug. However, whatever the proposed treatment, limitations such as adverse effects and the emergence of drug resistance justify the search for new ...
Philippe M. Loiseau, Gillian Barratt
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Expert Opinion on Therapeutic Patents, 1999
Creating effective targeted drug delivery strategies is an integral component of the overall process of drug development. The four key requirements of an effective drug delivery system are retain, evade, target and release. Increasing the therapeutic index (TI) of a delivered compound by selectively delivering it to target areas is a goal that has many
Jeffrey K Mills, David Needham
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Creating effective targeted drug delivery strategies is an integral component of the overall process of drug development. The four key requirements of an effective drug delivery system are retain, evade, target and release. Increasing the therapeutic index (TI) of a delivered compound by selectively delivering it to target areas is a goal that has many
Jeffrey K Mills, David Needham
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Companies Targeting Drug Delivery
Nature Biotechnology, 1990R, Burns, G, Rifkin
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2016
Drug delivery is defined as mechanisms to introduce pharmaceutical compounds to human in order to achieve therapeutic effects. We have come a long way since chewing medicinal plants and inhaling soot from medicinal substance were the only form of drug delivery. These approaches lacked consistency and uniformity of drug delivery.
Varsha Gupta +3 more
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Drug delivery is defined as mechanisms to introduce pharmaceutical compounds to human in order to achieve therapeutic effects. We have come a long way since chewing medicinal plants and inhaling soot from medicinal substance were the only form of drug delivery. These approaches lacked consistency and uniformity of drug delivery.
Varsha Gupta +3 more
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1991
A new perspective for drug delivery research internalization and sorting of macromolecules transport of macromolecule across the capillary endothelium pharmacokinetics in drug targeting: specific implications to targeting via prodrugs engineering proteins and peptides for drug delivery soluble polymers as targetable drug carriers systemic delivery of ...
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A new perspective for drug delivery research internalization and sorting of macromolecules transport of macromolecule across the capillary endothelium pharmacokinetics in drug targeting: specific implications to targeting via prodrugs engineering proteins and peptides for drug delivery soluble polymers as targetable drug carriers systemic delivery of ...
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Targeted drug delivery systems for the intracellular delivery of macromolecular drugs
Drug Discovery Today, 2003Gerben A, Koning, Gert, Storm
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