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Brain‐targeting drug delivery systems
WIREs Nanomedicine and Nanobiotechnology, 2022AbstractBrain diseases, including neurodegenerative diseases, acute ischemic stroke and brain tumors, have become a major health problem and a huge burden on society with high morbidity and mortality. However, most of the current therapeutic drugs can only relieve the symptoms of brain diseases, and it is difficult to achieve satisfactory therapeutic ...
Peixin Liu, Chen Jiang
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Peptide‐mediated targeted drug delivery
Medicinal Research Reviews, 2010AbstractTargeted drug delivery to specific group of cells offers an attractive strategy to minimize the undesirable side effects and achieve the therapeutic effect with a lower dose. Both linear and cyclic peptides have been explored as trafficking moiety due to ease of synthesis, structural simplicity, and low probability of undesirable immunogenicity.
Sumit, Majumdar, Teruna J, Siahaan
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Nanotechnology based targeted drug delivery
2010 Annual International Conference of the IEEE Engineering in Medicine and Biology, 2010NANOTECHNOLOGY is having a great impact on many industrial applications, such as manufacturing, semiconductors, nanostructured materials and biotechnology. As relates to the latter, nanobiotechnology focuses on the ability to work at the molecular and atomic level to fabricate structures combining biological materials and synthetic materials, taking ...
RUGGIERO, CARMELINA +2 more
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Targeted drug delivery to macrophages
Expert Opinion on Drug Delivery, 2013Targeted drug delivery to the macrophages appears to be an attractive proposition to improve therapeutic efficacy of enclosed drug. Thus, macrophages can be exploited as Trojan horses for targeted drug delivery. Nanocarriers can migrate across the different membrane barriers and release their drug cargo at sites of infection.This review discusses the ...
Narendra K, Jain +2 more
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Targeted drug delivery to melanoma
Advanced Drug Delivery Reviews, 2018Melanoma derived from melanocytes is the most aggressive genre of skin cancer. Although the considerable advancement in the study of human cancer biology and drug discovery, most advanced melanoma patients are inevitably unable to be cured. With the emergence of nanotechnology, the use of nano-carriers is widely expected to alter the landscape of ...
Das, Manisit +3 more
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1991
A new perspective for drug delivery research internalization and sorting of macromolecules transport of macromolecule across the capillary endothelium pharmacokinetics in drug targeting: specific implications to targeting via prodrugs engineering proteins and peptides for drug delivery soluble polymers as targetable drug carriers systemic delivery of ...
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A new perspective for drug delivery research internalization and sorting of macromolecules transport of macromolecule across the capillary endothelium pharmacokinetics in drug targeting: specific implications to targeting via prodrugs engineering proteins and peptides for drug delivery soluble polymers as targetable drug carriers systemic delivery of ...
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Companies Targeting Drug Delivery
Nature Biotechnology, 1990R, Burns, G, Rifkin
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Drug Targets, Drug Effectors, and Drug Targeting and Delivery
2012The chemotherapy of leishmaniases has undergone significant improvements during the last decade with the use of liposomal amphotericin B formulation (AmBisome®) and miltefosine as the first orally active drug. However, whatever the proposed treatment, limitations such as adverse effects and the emergence of drug resistance justify the search for new ...
Philippe M. Loiseau, Gillian Barratt
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Antibody–drug conjugates: Smart chemotherapy delivery across tumor histologies
Ca-A Cancer Journal for Clinicians, 2022Paolo Tarantino +2 more
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