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Clinical Advances and Perspectives in Targeted Radionuclide Therapy [PDF]
Pharmaceutics, 2023 Targeted radionuclide therapy has become increasingly prominent as a nuclear medicine subspecialty. For many decades, treatment with radionuclides has been mainly restricted to the use of iodine-131 in thyroid disorders.
Nicolas Lepareur +3 more
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212Pb in targeted radionuclide therapy: a review [PDF]
EJNMMI Radiopharmacy and ChemistryBackground The selective delivery of α-emitting radionuclides is emerging as a highly effective form of cancer therapy. With a short range and high cytotoxicity, α-particles can selectively kill cancerous cells whilst minimising harm to surrounding ...
Jarred Michael Scaffidi-Muta +1 more
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A brief overview of targeted radionuclide therapy trials in 2022 [PDF]
Frontiers in Nuclear Medicine, 2023 There is a growing use of radionuclide therapy for the medical care of oncology patients, where radioactive pharmaceuticals are used to target and treat various cancer types.
Aidan Healy +3 more
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Targeted radionuclide therapy in endocrine-related cancers: advances in the last decade [PDF]
Frontiers in Endocrinology, 2023 Targeted radionuclide therapy plays an increasingly important role in managing endocrine-related tumors and significantly advances the therapeutic landscape for patients with these diseases.
Taymeyah Al-Toubah +4 more
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DNA Repair Inhibitors: Potential Targets and Partners for Targeted Radionuclide Therapy [PDF]
Pharmaceutics, 2023 The present review aims to explore the potential targets/partners for future targeted radionuclide therapy (TRT) strategies, wherein cancer cells often are not killed effectively, despite receiving a high average tumor radiation dose.
Honoka Obata +2 more
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Editorial for the Special Issue “Molecular Biology in Targeted Radionuclide Therapy Radiopharmaceutical Design” [PDF]
Current Issues in Molecular BiologyTargeted radionuclide therapy (TRT) is gaining wide and rapid acceptance in clinical practice as it can deliver alpha or beta irradiation to a tumor-associated target which may be present in the tumor cell itself or in the microenvironment [...]
Carlo Aprile +3 more
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Targeted Radionuclide Therapy Activates Prodrugs for Treating Metastasis [PDF]
ACS Central ScienceZhibin Guo +8 more
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Radiometals in Imaging and Therapy: Highlighting Two Decades of Research
Pharmaceuticals, 2023 The present article highlights the important progress made in the last two decades in the fields of molecular imaging and radionuclide therapy. Advancements in radiometal-based positron emission tomography, single photon emission computerized tomography,
Shalini Sharma, Mukesh K. Pandey
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Bismuth-213 for Targeted Radionuclide Therapy: From Atom to Bedside
Pharmaceutics, 2021 In contrast to external high energy photon or proton therapy, targeted radionuclide therapy (TRNT) is a systemic cancer treatment allowing targeted irradiation of a primary tumor and all its metastases, resulting in less collateral damage to normal ...
Stephen Ahenkorah +7 more
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Pharmaceutics, 2023 The widespread use of peptide receptor radionuclide therapy (PRRT) represents a major therapeutic breakthrough in nuclear medicine, particularly since the introduction of 177Lu-radiolabeled somatostatin analogs. These radiopharmaceuticals have especially
Léa Rubira +4 more
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