Results 11 to 20 of about 13,805 (198)
Radionuclides for Targeted Therapy: Physical Properties
Molecules, 2022 A search in PubMed revealed that 72 radionuclides have been considered for molecular or functional targeted radionuclide therapy. As radionuclide therapies increase in number and variations, it is important to understand the role of the radionuclide and ...
Caroline Stokke +2 more
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Introduction to radiobiology of targeted radionuclide therapy [PDF]
Frontiers in Medicine, 2015 During the last decades, new radionuclide-based targeted therapies have emerged as efficient tools for cancer treatment. Targeted radionuclide therapies (TRT) are based on a multidisciplinary approach that involves the cooperation of specialists in ...
Jean-Pierre ePOUGET +6 more
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Prospects in folate receptor-targeted radionuclide therapy [PDF]
Frontiers in Oncology, 2013 Targeted radionuclide therapy is based on systemic application of particle-emitting radiopharmaceuticals which are directed towards a specific tumor-associated target. Accumulation of the radiopharmaceutical in targeted cancer cells results in high doses
Cristina eMüller +2 more
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Targeted radionuclide therapy [PDF]
Medical Physics, 2008 Targeted radionuclide therapy (TRT) seeks molecular and functional targets within patient tumor sites. A number of agents have been constructed and labeled with beta, alpha, and Auger emitters. Radionuclide carriers spanning a broad range of sizes; e.g., antibodies, liposomes, and constructs such as nanoparticles have been used in these studies. Uptake,
Lawrence E. Williams +2 more
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Targeted Radionuclide Therapy of Cancer and Infections. [PDF]
Int J Mol Sci, 2023 Targeted radionuclide therapy (TRT) has been burgeoning worldwide, with several radiopharmaceuticals for the treatment of metastatic cancers being approved for clinical use [...]
van der Wal BCH, Dadachova E.
europepmc +4 more sources
Targeted Radionuclide Therapy [PDF]
Cancers, 2011 Targeted radiotherapy is an evolving and promising modality of cancer treatment. The killing of cancer cells is achieved with the use of biological vectors and appropriate radionuclides. Among the many advantages of this approach are its selectiveness in delivering the radiation to the target, relatively less severe and infrequent side effects, and the
Ersahin, Devrim +2 more
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Targeted radionuclide therapy frontiers in theranostics [PDF]
Frontiers in Bioscience, 2017 The concept of targeted radionuclide therapy (TRT) relies on the use of injected nuclear medicine as treating agents, targeted at the cellular or molecular level. The growth of the interest in TRT was stimulated by the advances in radionuclide production and labeling as well as by the improvement in the knowledge of appropriate and specific molecular ...
Francesca Gallivanone 1 +7 more
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Pharmaceutics, 2021 In recent years, radionuclide therapy (RT) and targeted radionuclide therapy (TRT) have gained great interest in cancer treatment. This is due to promising results obtained in both preclinical and clinical studies.
Tyrillshall S. T. Damiana +1 more
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Combination Therapies with PRRT
Pharmaceuticals, 2021 Peptide receptor radionuclide therapy (PRRT) is a successful targeted radionuclide therapy in neuroendocrine tumors (NETs). However, complete responses remain elusive.
Anna Yordanova, Hojjat Ahmadzadehfar
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Combination Strategies to Improve Targeted Radionuclide Therapy [PDF]
Journal of Nuclear Medicine, 2020 In recent years, targeted radionuclide therapy (TRT) has emerged as a promising strategy for cancer treatment. In contrast to conventional radiotherapy, TRT delivers ionizing radiation to tumors in a targeted manner, reducing the dose that healthy tissues are exposed to.
Chan, T +3 more
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