Results 171 to 180 of about 1,721,954 (363)

Multiplex single‐cell profiling of putative cancer stem cell markers ALDH1, SOX9, SOX2, CD44, CD133 and CD15 in endometrial cancer

Molecular Oncology, EarlyView.
Cancer stem cells are associated with aggressive disease, but a deep characterization of such markers is lacking in endometrial cancer. This study uses imaging mass cytometry to explore putative cancer stem cell markers in endometrial tumors and corresponding organoid models.
Hilde E. Lien, Marta E. Hjelmeland, Hege F. Berg, Rose M. Gold, Kathrine Woie, Lars A. Akslen, Ingfrid S. Haldorsen, Camilla Krakstad   +7 more
wiley   +1 more source

An overview of the research evidence on ethnicity and communication in healthcare [PDF]

, 2005
• The aim of the present study was to identify and review the available research evidence on 'ethnicity and communication' in areas relevant to ensuring effective provision of mainstream services (e.g.
Clay, Diane, Gumber, Anil, HASH(0x55aa093742c0), Johnson, Mark R. D., Jones, Kip, Shaw, A., Szczepura, Ala   +6 more
core  

The effect of environmental factors in biofilm and phage interactions in Agent Based Model [PDF]

arXiv
As antibiotic resistance continues to pose a significant threat to public health, alternative treatments are urgently needed. Phage therapy, which utilizes bacteriophages to specifically target bacterial pathogens, has emerged as a promising solution.
arxiv  

Consideration on treatment of pain. Treatment of pain with non-steroidal anti-inflammatory agents. (Particularly on targeting therapy).

, 1986
Akira Yanagawa
openalex   +2 more sources

Photodynamic Tumor Therapy: Mitochondrial Benzodiazepine Receptors as a Therapeutic Target [PDF]

, 1998
Ajay Verma, Stephen L. Facchina, David J. Hirsch, Shiyu Song, Larry F. Dillahey, Jerry R. Williams, Solomon H. Snyder   +6 more
openalex   +1 more source

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Stochastic variation in the FOXM1 transcription program mediates replication stress tolerance

Molecular Oncology, EarlyView.
Cellular heterogeneity is a major cause of drug resistance in cancer. Segeren et al. used single‐cell transcriptomics to investigate gene expression events that correlate with sensitivity to the DNA‐damaging drugs gemcitabine and prexasertib. They show that dampened expression of transcription factor FOXM1 and its target genes protected cells against ...
Hendrika A. Segeren, Kathryn A. Wierenga, Frank M. Riemers, Elsbeth A. van Liere, Bart Westendorp   +4 more
wiley   +1 more source

A Potential Approach for Gene Therapy Targeting Hepatoma Using a Liver-Specific Promoter on a Retroviral Vector.

, 1991
Shigeki Kuriyama, Masahide Yoshikawa, Shigeaki Ishizaka, Tadasu Tsujii, Kazuhiro Ikenaka, Tetsushi Kagawa, Noriyuki Morita, Katsuhiko Mikoshiba   +7 more
openalex   +2 more sources

Retrovirus-Mediated Suicide Gene Prodrug Therapy Targeting Thyroid Carcinoma Using a Thyroid-Specific Promoter [PDF]

, 1998
Vera Braiden, Yuji Nagayama, Makoto Iitaka, Hiroyuki Namba, Masami Niwa, Shunichi Yamashita   +5 more
openalex   +1 more source

CircCCNB1 inhibits vasculogenic mimicry by sequestering NF90 to promote miR‐15b‐5p and miR‐7‐1‐3p processing in nasopharyngeal carcinoma

Molecular Oncology, EarlyView.
CircCCNB1 expression is down‐regulated in nasopharyngeal carcinoma (NPC); thus, less NF90 protein is bound to circCCNB1 and more binds to pri‐miRNAs, blocking their (pri‐miRNAs) binding to DGCR8 and inhibiting the processing and generation of miR‐15b‐5p/miR‐7‐1‐3p. Furthermore, decreased miR‐15b‐5p/miR‐7‐1‐3p promotes the expression of the target genes
Chunmei Fan, Fenghua Tan, Jie Wu, Zhaoyang Zeng, Wenjia Guo, He Huang, Wei Xiong   +6 more
wiley   +1 more source