Results 181 to 190 of about 9,755,316 (348)

Dose‐dependent induction of epithelial‐mesenchymal transition in 3D melanoma models by non‐thermal plasma treatment

Molecular Oncology, EarlyView.
Non‐thermal plasma treatment of melanoma cells induced epithelial‐mesenchymal transition (EMT) in a dose‐dependent fashion. This report highlights the critical need to further investigate potential adverse effects of non‐thermal plasma for cancer therapy and to optimize treatment parameters for clinical translation. Despite the promising results of non‐
Eline Biscop, Edgar Cardenas De La Hoz, Hanne Verswyvel, Joey De Backer, Ho Wa Lau, Angela Privat‐Maldonado, Wim Vanden Berghe, Steve Vanlanduit, Evelien Smits, Annemie Bogaerts, Abraham Lin   +10 more
wiley   +1 more source

Systemic sclerosis: current pathogenetic concepts and future prospects for targeted therapy

, 1996
Christopher P. Denton, C. M. Black, J H Korn, B. de Crombrugghe   +3 more
openalex   +1 more source

Chromosomes are target sites for photodynamic therapy as demonstrated by subcellular laser microirradiation [PDF]

, 2000
Liang Hong, Tuyen Do, Sanaz Kasravi, Parnaz Aurasteh, Andrea Nguyen, Andy Huang, Zhuotong Wang, Michael W. Berns   +7 more
openalex   +1 more source

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

Molecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed, Lucas Mani, Muhammad Bilal Mirza, Ashtyn McAdoo, Takahito Kondo, Hidenori Tanaka, Nicole Meeks, Eben Rosenthal, Marisa Hom   +8 more
wiley   +1 more source

Succinate supplementation alleviates liver cancer by inhibiting the FN1/SQLE axis-mediated cholesterol biosynthesis

iScience
Summary: Succinate is a crucial metabolite in the TCA cycle and contributes to cancer development. However, the role of exogenous succinate in hepatocellular carcinoma (HCC) is unclear.
Shuyuan Chang, Ayaka Tomii, Yunfei Zhou, Xun Yang, Yihong Dong, Jun Yan, Aodi Wu, Yumeng Wang, Qingxin Zhang, Hongxue Meng, Lei Yu, Wei Sun, Dabin Liu   +12 more
doaj  

MET-dependent solid tumours — molecular diagnosis and targeted therapy

Nature Reviews Clinical Oncology, 2020
Robin Guo, Jia Luo, Jason C. Chang, N. Rekhtman, M. Arcila, A. Drilon   +5 more
semanticscholar   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

Molecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho, Yubin Hah, Eunsik Yun, Hye In Ka, Aram Lee, Sora Han, Dawn Lee, Sung Wook Kim, Jong Hoon Park, Byung Su Kwon, Young Yang, Jongmin Kim   +11 more
wiley   +1 more source

Message Therapy: Gene Therapy That Targets mRNA Sequence and Stability

, 1997
Karen Kozarsky, Larry A. Couture
openalex   +1 more source

Proteogenomic Landscape of Breast Cancer Tumorigenesis and Targeted Therapy

Cell, 2020
Karsten Krug, Eric J. Jaehnig, S. Satpathy, L. Blumenberg, A. Karpova, M. Anurag, George Miles, Philipp Mertins, Philipp Mertins, Y. Geffen, Lauren C. Tang, Lauren C. Tang, David I Heiman, Song Cao, Y. Maruvka, Jonathan T. Lei, Chen Huang, Ramani Kothadia, A. Colaprico, Chet Birger, Jarey H. Wang, Yongchao Dou, Bo Wen, Zhiao Shi, Yuxing Liao, M. Wiznerowicz, M. Wiznerowicz, Matthew A. Wyczalkowski, X. Chen, Jacob J. Kennedy, A. Paulovich, M. Thiagarajan, C. Kinsinger, Tara Hiltke, Emily Boja, M. Mesri, A. Robles, H. Rodriguez, Thomas F. Westbrook, L. Ding, G. Getz, G. Getz, K. Clauser, D. Fenyö, Kelly V. Ruggles, Bing Zhang, D. Mani, Steve Carr, M. Ellis, Michael A. Gillette, Michael A. Gillette, S. Avanessian, S. Cai, Daniel W. Chan, Xian Chen, N. Edwards, A. Hoofnagle, M. H. Kane, K. Ketchum, E. Kuhn, D. Levine, Shunqiang Li, D. Liebler, Tao Liu, Jingqin R Luo, Subha Madhavan, Christopher G. Maher, J. Mcdermott, P. McGarvey, Mauricio Oberti, A. Pandey, S. Payne, D. Ransohoff, Robert C. Rivers, K. Rodland, P. Rudnick, M. Sanders, K. Shaw, I. Shih, R. Slebos, Richard D. Smith, Michael Snyder, S. Stein, D. Tabb, Ratna R. Thangudu, Stefani N. Thomas, Yue Wang, F. White, Jeffrey R. Whiteaker, Gordon A. Whiteley, Hui Zhang, Zhen Zhang, Yingming Zhao, Hengying Zhu, L. Zimmerman   +94 more
semanticscholar   +1 more source

Emerging mechanisms and targeted therapy of ferroptosis in cancer.

Molecular Therapy, 2021
Haiyan Wang, Yan Cheng, Chao Mao, Shuang Liu, D. Xiao, Jun Huang, Y. Tao   +6 more
semanticscholar   +1 more source