Results 271 to 280 of about 1,721,954 (363)

The epidermal growth factor receptor as a target for cancer therapy. [PDF]

, 2001
John Mendelsohn
openalex   +1 more source

CINs of the cytoplasm: dissecting dsRNA signaling in chromosomal instability

Molecular Oncology, EarlyView.
Micronuclei, formed during cell division in chromosomal instability settings, rupture and lead to the accumulation of immunogenic double‐stranded RNA in the cytoplasm, activating MAVS‐dependent interferon signaling and innate antitumor immunity.
Aglaia Skolariki, Rose L. Jady‐Clark, Eileen E. Parkes   +2 more
wiley   +1 more source

Advances in Immunotherapy and Targeted Therapy of Malignant Melanoma. [PDF]

Biomedicines
Wang X, Ma S, Zhu S, Zhu L, Guo W.
europepmc   +1 more source

TRPM8 levels determine tumor vulnerability to channel agonists

Molecular Oncology, EarlyView.
TRPM8 is a Ca2+ permissive channel. Regardless of the amount of its transcript, high levels of TRPM8 protein mark different tumors, including prostate, breast, colorectal, and lung carcinomas. Targeting TRPM8 with channel agonists stimulates inward calcium currents followed by emptying of cytosolic Ca2+ stores in cancer cells.
Alessandro Alaimo, Francesco Giuseppe Carbone, Kristi Buzo, Nicole Annesi, Sacha Genovesi, Annalisa Lorenzato, Karen Widmann, Michela Libergoli, Elisa Marmocchi, Giovanni Bertalot, Alberto Brolese, Mauro Giulio Papotti, Luca Molinaro, Orazio Caffo, Mattia Barbareschi, Alberto Bardelli, Alessandro Romanel, Sabrina Arena, Andrea Lunardi   +18 more
wiley   +1 more source

Targeted therapy in gastric cancer [PDF]

, 2016

core   +1 more source

Divide and Conquer-Targeted Therapy for Triple-Negative Breast Cancer. [PDF]

Int J Mol Sci
Nedeljković M, Vuletić A, Mirjačić Martinović K.   +2 more
europepmc   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

Targeted photodynamic therapy of breast cancer cells using antibody–phthalocyanine–gold nanoparticle conjugates [PDF]

, 2011
Cook, MJ, Edwards, DR, Moreno, M, Russell, DA, Stuchinskaya, T   +4 more
core   +1 more source

FGFR as a Predictive Marker for Targeted Therapy in Gastrointestinal Malignancies: A Systematic Review. [PDF]

J Gastrointest Cancer
Seraji N, Berger I.
europepmc   +1 more source

Radiopharmaceuticals for Targeted Tumor Diagnosis and Therapy

, 2000
Robert Waibel, Ilse Novak‐Hofer, Roger Schibli, Peter Bläuenstein, Elisa García‐Garayoa, R. Schwarzbach, Kurt Zimmermann, Raimo Pellikka, Olga Gasser, Alain Blanc, Matthias Brühlmeier, P. August Schubiger   +11 more
openalex   +2 more sources