Taste bud formation depends on taste nerves [PDF]
eLife, 2019 It has been known for more than a century that, in adult vertebrates, the maintenance of taste buds depends on their afferent nerves. However, the initial formation of taste buds is proposed to be nerve-independent in amphibians, and evidence to the ...
Di Fan +3 more
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Role of Transient Receptor Potential Vanilloid 1 in Sonic Hedgehog-Dependent Taste Bud Differentiation [PDF]
Life, 2022 Taste bud cell differentiation is extremely important for taste sensation. Immature taste bud cells cannot function during taste perception transmission to the nerve.
Yun-Hee Rhee +8 more
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Bisphosphonate affects the behavioral responses to HCl by disrupting farnesyl diphosphate synthase in mouse taste bud and tongue epithelial cells [PDF]
Scientific Reports, 2022 Little is known about the molecular mechanisms underlying drug-induced taste disorders, which can cause malnutrition and reduce quality of life.
Asami Oike +9 more
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Longitudinal imaging of the taste bud in vivo with two-photon laser scanning microscopy. [PDF]
PLoS ONETaste bud cells in the tongue transduce taste information from chemicals in food and transmit this information to gustatory neurons in the geniculate ganglion that innervate taste buds. The peripheral taste system is a dynamic environment where taste bud
Brittany N Walters +3 more
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Novel, Fully Characterised Bovine Taste Bud Cells of Fungiform Papillae [PDF]
Cells, 2021 Current understanding of functional characteristics and biochemical pathways in taste bud cells have been hindered due the lack of long-term cultured cells. To address this, we developed a holistic approach to fully characterise long term cultured bovine
Habtom Ftuwi +2 more
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The duct of von Ebner’s glands is a source of Sox10+ taste bud progenitors and susceptible to pathogen infections [PDF]
Frontiers in Cell and Developmental BiologyIntroductionWe have recently demonstrated that Sox10-expressing (Sox10+) cells give rise to mainly type-III neuronal taste bud cells that are responsible for sour and salt taste.
Wenxin Yu +14 more
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Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function [PDF]
eLife, 2021 Embryonic taste bud primordia are specified as taste placodes on the tongue surface and differentiate into the first taste receptor cells (TRCs) at birth. Throughout adult life, TRCs are continually regenerated from epithelial progenitors. Sonic hedgehog
Erin J Golden +8 more
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β-catenin is required for taste bud cell renewal and behavioral taste perception in adult mice. [PDF]
PLoS Genetics, 2017 Taste stimuli are transduced by taste buds and transmitted to the brain via afferent gustatory fibers. Renewal of taste receptor cells from actively dividing progenitors is finely tuned to maintain taste sensitivity throughout life.
Dany Gaillard +5 more
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In Vitro Functional Characterization of Type-I Taste Bud Cells as Monocytes/Macrophages-like Which Secrete Proinflammatory Cytokines. [PDF]
Int J Mol Sci, 2023 Hichami A +4 more
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Whole transcriptome profiling of taste bud cells [PDF]
Scientific Reports, 2017 Analysis of single-cell RNA-Seq data can provide insights into the specific functions of individual cell types that compose complex tissues. Here, we examined gene expression in two distinct subpopulations of mouse taste cells: Tas1r3-expressing type II ...
Sunil K. Sukumaran +5 more
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